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Keeley Cure
The Keeley Institute, known for its Keeley Cure or Gold Cure, was a commercial medical operation that offered treatment to alcoholics from 1879 to 1965. Though at one time there were more than 200 branches in the United States and Europe, the original institute was founded by Leslie Keeley in Dwight, Illinois, United States. The Keeley Institute's location in Dwight, Illinois, had a major influence on the development of Dwight as a village, though only a few indications of its significance remain in the village. After Keeley's death the institute began a slow decline but remained in operation under John R. Oughton, and, later, his son. The Institute offered the internationally known Keeley Cure, a cure which drew sharp criticism from those in the mainstream medical profession. It was wildly popular in the late 1890s. Thousands of people came to Dwight to be cured of alcoholism; thousands more sent for the mail-order oral liquid form which they took in the privacy of their homes. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leslie Keeley
Leslie Enraught Keeley (June 10, 1836 – February 21, 1900) was an American physician, originator of the Keeley Cure. Biography He was born in Potsdam, New York, on June 10, 1836. Keeley graduated at the Rush Medical College, Chicago, in 1863, and later entered the Union Army as a surgeon. At the end of the war he moved to Dwight, Illinois, where he began his private medical practice. There, in 1880, he opened a sanatorium for persons addicted to the immoderate use of alcohol and opium. He asserted that "Alcoholism is a disease and I can cure it." His treatment, referred to as "Double Chloride of Gold", centered on a secret preparation that he said contained bichloride of gold. However, chemical analysis revealed that the proprietary tonic contained 27.55% alcohol plus ammonium chloride, aloin and tincture of cinchona but no gold. His hypodermic injections contained sulfate of strychnine, atropine and boracic acid. In 1890, Keeley began selling franchises and by 1893 there ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Faulkner
William Cuthbert Faulkner (; September 25, 1897 – July 6, 1962) was an American writer known for his novels and short stories set in the fictional Yoknapatawpha County, based on Lafayette County, Mississippi, where Faulkner spent most of his life. A Nobel Prize laureate, Faulkner is one of the most celebrated writers of American literature and is considered the greatest writer of Southern literature. Born in New Albany, Mississippi, Faulkner's family moved to Oxford, Mississippi when he was a young child. With the outbreak of World War I, he joined the Royal Canadian Air Force but did not serve in combat. Returning to Oxford, he attended the University of Mississippi for three semesters before dropping out. He moved to New Orleans, where he wrote his first novel '' Soldiers' Pay'' (1925). He went back to Oxford and wrote '' Sartoris'' (1927), his first work set in the fictional Yoknapatawpha County. In 1929, he published ''The Sound and the Fury''. The following year, he ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Memphis, Tennessee
Memphis is a city in the U.S. state of Tennessee. It is the seat of Shelby County in the southwest part of the state; it is situated along the Mississippi River. With a population of 633,104 at the 2020 U.S. census, Memphis is the second-most populous city in Tennessee, after Nashville. Memphis is the fifth-most populous city in the Southeast, the nation's 28th-largest overall, as well as the largest city bordering the Mississippi River. The Memphis metropolitan area includes West Tennessee and the greater Mid-South region, which includes portions of neighboring Arkansas, Mississippi and the Missouri Bootheel. One of the more historic and culturally significant cities of the Southern United States, Memphis has a wide variety of landscapes and distinct neighborhoods. The first European explorer to visit the area of present-day Memphis was Spanish conquistador Hernando de Soto in 1541. The high Chickasaw Bluffs protecting the location from the waters of the Mississipp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Therapeutic Community
Therapeutic community is a participative, group-based approach to long-term mental illness, personality disorders and drug addiction. The approach was usually residential, with the clients and therapists living together, but increasingly residential units have been superseded by day units. It is based on milieu therapy principles, and includes group psychotherapy as well as practical activities. Therapeutic communities have gained some reputation for success in rehabilitation and patient satisfaction in Britain and abroad. In Britain, 'democratic analytic' therapeutic communities have tended to specialise in the treatment of moderate to severe personality disorders and complex emotional and interpersonal problems. The evolution of therapeutic communities in the United States has followed a different path with hierarchically arranged communities (or concept houses) specialising in the treatment of drug and alcohol dependence. History Antecedents There are several antecedents to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atropine
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings. Common side effects include a dry mouth, large pupils, urinary retention, constipation, and a fast heart rate. It should generally not be used in people with angle closure glaucoma. While there is no evidence that its use during pregnancy causes birth defects, that has not been well studied. It is likely safe during breastfeeding. It is an antimuscarinic (a type of anticholinergic) that works by inhibiting the parasympathetic nervous system. Atropine occurs n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Willow Bark
Willows, also called sallows and osiers, from the genus ''Salix'', comprise around 400 speciesMabberley, D.J. 1997. The Plant Book, Cambridge University Press #2: Cambridge. of typically deciduous trees and shrubs, found primarily on moist soils in cold and temperate regions. Most species are known as willow, but some narrow-leaved shrub species are called osier, and some broader-leaved species are referred to as sallow (from Old English ''sealh'', related to the Latin word ''salix'', willow). Some willows (particularly arctic and alpine species) are low-growing or creeping shrubs; for example, the dwarf willow (''Salix herbacea'') rarely exceeds in height, though it spreads widely across the ground. Description Willows all have abundant watery bark sap, which is heavily charged with salicylic acid, soft, usually pliant, tough wood, slender branches, and large, fibrous, often stoloniferous roots. The roots are remarkable for their toughness, size, and tenacity to live, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apomorphine
Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non- selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors. It also acts as an antagonist of 5-HT2 and α-adrenergic receptors with high affinity. The compound is historically a morphine decomposition product made by boiling morphine with concentrated acid, hence the ''-morphine'' suffix. Contrary to its name, apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors. The ''apo-'' prefix relates to it being a morphine derivative ("omesfrom morphine"). Historically, apomorphine has been tried for a variety of uses, including as a way to relieve anxiety and craving in alcoholics, an emetic (to induce vomiting), for treating stereotypies (repeated behaviour) in farmyard animals, and more recently in treating erectile dysfunction. Currently, apomorphine is used in the treatment of Pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strychnine
Strychnine (, , US chiefly ) is a highly toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart and bowel stimulant and performance-enhancing drug. The most common source is from the seeds of the ''Strychnos nux-vomica'' tree. Biosynthesis Strychnine is a terpene indole alkaloid belonging to the ''Strychnos'' family of '' Corynanthe'' alkaloids, and it is derived from tryptamine and secologanin. The biosynthesis of strychine was solved in 2022. The enzyme, strictosidine synthase, catalyzes the condensation of tryptamine and secologanin, followed by a Pictet-Spengler reaction to form strictosidine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alcohol (drug)
Alcohol, sometimes referred to by the chemical name ''ethanol'', is a depressant, depressant drug that is the active ingredient in alcoholic drink, drinks such as beer, wine, and distilled spirits (hard liquor). It is one of the oldest and most commonly consumed recreational drugs, causing the characteristic effects of alcohol intoxication ("drunkenness"). Among other effects, alcohol produces happiness and euphoria, anxiolytic, decreased anxiety, increased sociability, sedation, impairment of cognitive, memory, motor control, motor, and sense, sensory function, and generalized depression of central nervous system (CNS) function. Ethanol is only one of several types of Alcohol (chemistry), alcohol, but it is the only type of alcohol that is found in alcoholic beverages or commonly used for recreational purposes; other alcohols such as methanol and isopropyl alcohol are significantly more toxicity, toxic. A mild, brief exposure to isopropanol, being only moderately more toxic tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Franchising
Franchising is based on a marketing concept which can be adopted by an organization as a strategy for business expansion. Where implemented, a franchisor licenses some or all of its know-how, procedures, intellectual property, use of its business model, brand, and rights to sell its branded products and services to a franchisee. In return, the franchisee pays certain fees and agrees to comply with certain obligations, typically set out in a franchise agreement. The word ''franchise'' is of Anglo-French derivation—from , meaning 'free'—and is used both as a noun and as a (transitive) verb. For the franchisor, use of a franchise system is an alternative business growth strategy, compared to expansion through corporate owned outlets or "chain stores". Adopting a franchise system business growth strategy for the sale and distribution of goods and services minimizes the franchisor's capital investment and liability risk. Franchising is rarely an equal partnership, especially in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time Capsule
A time capsule is a historic cache of goods or information, usually intended as a deliberate method of communication with future people, and to help future archaeologists, anthropologists, or historians. The preservation of holy relics dates back for millennia, but the practice of preparing and preserving a collection of everyday artifacts and messages to the future appears to be a more recent practice. Time capsules are sometimes created and buried during celebrations such as a world's fair, a cornerstone laying for a building, or at other ceremonies. History Early examples It is widely debated when time capsules were first used, but the concept is fairly simple, and the idea and first use of time capsules could be much older than is currently documented. The term "time capsule" appears to be a relatively recent coinage dating from 1938. Around 1761, some dated artifacts were placed inside the hollow copper grasshopper weathervane, itself dating from 1742, atop historic Fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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