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Karl Albert Hasselbalch
Karl Albert Hasselbalch (; 1 November 1874 – 19 September 1962) was a Danish physician and chemist known for his work on the Henderson–Hasselbalch equation. Early life and education Hasselbalch was born in Åstrup, near Hjørring, Denmark on 1 November 1874. Hasselbalch received his medical degree in 1898 and his doctorate in 1899 for his thesis on the respiratory metabolism in the chicken embryo. Career Hasselbalch was a pioneer in the use of pH measurement in medicine (with Christian Bohr, father of Niels Bohr), and he described how the affinity of blood for oxygen was dependent on the concentration of carbon dioxide. He was also first to determine the pH of blood. In 1916, he converted the 1908 equation of Lawrence Joseph Henderson to logarithmic form, which is now known as the Henderson–Hasselbalch equation In chemistry and biochemistry, the Henderson–Hasselbalch equation :\ce = \ceK_\ce + \log_ \left( \frac \right) relates the pH of a chemical solution of a ...
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Henderson–Hasselbalch Equation
In chemistry and biochemistry, the Henderson–Hasselbalch equation :\ce = \ceK_\ce + \log_ \left( \frac \right) relates the pH of a chemical solution of a weak acid to the numerical value of the acid dissociation constant, ''K''a, of acid and the ratio of the concentrations, \frac of the acid and its conjugate base in an equilibrium. : \mathrm For example, the acid may be acetic acid :\mathrm The Henderson–Hasselbalch equation can be used to estimate the pH of a buffer solution by approximating the actual concentration ratio as the ratio of the analytical concentrations of the acid and of a salt, MA. The equation can also be applied to bases by specifying the protonated form of the base as the acid. For example, with an amine, \mathrm :\mathrm Derivation, assumptions and limitations A simple buffer solution consists of a solution of an acid and a salt of the conjugate base of the acid. For example, the acid may be acetic acid and the salt may be sodium acetate. Th ...
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Hjørring
Hjørring () is a town on the island of Vendsyssel-Thy at the top of the Jutland peninsula in northern Denmark. It is the main town and the administrative seat of Hjørring Municipality in the North Jutland Region. The population is 25,644 (according to an official census carried on 1 January 2022).BY3: Population 1. January by urban areas, area and population density
The Mobile Statbank from
It is also one of Denmark's oldest towns, having celebrated its 750th anniversary as a market town in 1993. Hjørring is centrally located in a sparsely populated area and serves as an urban center for large parts of especially the western and centr ...
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Doctorate
A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''licentia docendi'' ("licence to teach"). In most countries, a research degree qualifies the holder to teach at university level in the degree's field or work in a specific profession. There are a number of doctoral degrees; the most common is the Doctor of Philosophy (PhD), awarded in many different fields, ranging from the humanities to scientific disciplines. In the United States and some other countries, there are also some types of technical or professional degrees that include "doctor" in their name and are classified as a doctorate in some of those countries. Professional doctorates historically came about to meet the needs of practitioners in a variety of disciplines. Many universities also award honorary doctorates to individuals d ...
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Chicken As Biological Research Model
Chickens (''Gallus gallus domesticus'') and their eggs have been used extensively as research models throughout the history of biology. Today they continue to serve as an important model for normal human biology as well as pathological disease processes. History Chicken embryos as a research model Human fascination with the chicken and its egg are so deeply rooted in history that it is hard to say exactly when avian exploration began. As early as 1400 BCE, ancient Egyptians artificially incubated chicken eggs to propagate their food supply. The developing chicken in the egg first appears in written history after catching the attention of the famous Greek philosopher, Aristotle, around 350 BCE. As Aristotle opened chicken eggs at various time points of incubation, he noted how the organism changed over time. Through his writing of '' Historia Animalium'', he introduced some of the earliest studies of embryology based on his observations of the chicken in the egg. Aristotle ...
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Christian Bohr
Christian Harald Lauritz Peter Emil Bohr (1855–1911) was a Danish physician, father of the physicist and Nobel laureate Niels Bohr, as well as the mathematician and football player Harald Bohr and grandfather of another physicist and Nobel laureate Aage Bohr. He married Ellen Adler in 1881. Personal life He wrote his first scientific paper, "Om salicylsyrens indflydelse på kødfordøjelsen" ("On salicylic acid's influence on the digestion of meat"), at the age of 22. He received his medical degree in 1880, studied under Carl Ludwig at University of Leipzig, took a Ph.D. in physiology and was appointed professor of physiology at the University of Copenhagen in 1886. On his religious views, Bohr was raised as a Lutheran. He was an atheist in later life. Christian Bohr is buried in the Assistens Kirkegård. Physiology In 1891, he was the first to characterize dead space. In 1904, Christian Bohr described the phenomenon, now called the Bohr effect, whereby hydrogen ions an ...
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Niels Bohr
Niels Henrik David Bohr (; 7 October 1885 – 18 November 1962) was a Danish physicist who made foundational contributions to understanding atomic structure and quantum theory, for which he received the Nobel Prize in Physics in 1922. Bohr was also a philosopher and a promoter of scientific research. Bohr developed the Bohr model of the atom, in which he proposed that energy levels of electrons are discrete and that the electrons revolve in stable orbits around the atomic nucleus but can jump from one energy level (or orbit) to another. Although the Bohr model has been supplanted by other models, its underlying principles remain valid. He conceived the principle of complementarity: that items could be separately analysed in terms of contradictory properties, like behaving as a wave or a stream of particles. The notion of complementarity dominated Bohr's thinking in both science and philosophy. Bohr founded the Institute of Theoretical Physics at the University of Cope ...
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Carbon Dioxide
Carbon dioxide (chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas. It is a trace gas in Earth's atmosphere at 421 parts per million (ppm), or about 0.04% by volume (as of May 2022), having risen from pre-industrial levels of 280 ppm. Burning fossil fuels is the primary cause of these increased CO2 concentrations and also the primary cause of climate change.IPCC (2022Summary for policy makersiClimate Change 2022: Mitigation of Climate Change. Contribution of Working Group III to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA Carbon dioxide is soluble in water and is found in groundwater, lakes, ice caps, ...
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Lawrence Joseph Henderson
Lawrence Joseph Henderson (June 3, 1878, Lynn, Massachusetts – February 10, 1942, Cambridge, Massachusetts) was a physiologist, chemist, biologist, philosopher, and sociologist. He became one of the leading biochemists of the early 20th century. His work contributed to the Henderson–Hasselbalch equation, used to calculate pH as a measure of acidity. Early life Lawrence Henderson was born in Lynn, Massachusetts the son of a business man Joseph Henderson and his wife. He entered Harvard at the age of 16 in 1894. His father was a ship chandler whose principal business was located in nearby Salem, but who also conducted business in Saint Pierre and Miquelon, a French Overseas collectivity off the coast of Canada. Career Lawrence Henderson graduated from Harvard College in 1898 and from Harvard Medical School in 1902, receiving the M.D. (Medical Doctor) degree cum laude. Then followed two years in chemical research at the University of Strasbourg with advanced scientific trai ...
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Danish Scientists
Danish may refer to: * Something of, from, or related to the country of Denmark People * A national or citizen of Denmark, also called a "Dane," see Demographics of Denmark * Culture of Denmark * Danish people or Danes, people with a Danish ancestral or ethnic identity * A member of the Danes, a Germanic tribe * Danish (name), a male given name and surname Language * Danish language, a North Germanic language used mostly in Denmark and Northern Germany * Danish tongue or Old Norse, the parent language of all North Germanic languages Food * Danish cuisine * Danish pastry, often simply called a "Danish" See also * Dane (other) * * Gdańsk * List of Danes * Languages of Denmark The Kingdom of Denmark has only one official language, Danish, the national language of the Danish people, but there are several minority languages spoken, namely Faroese, German, and Greenlandic. A large majority (about 86%) of Danes also s ... {{disambiguation Language ...
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1874 Births
Events January–March * January 1 – New York City annexes The Bronx. * January 2 – Ignacio María González becomes head of state of the Dominican Republic for the first time. * January 3 – Third Carlist War – Battle of Caspe: Campaigning on the Ebro in Aragon for the Spanish Republican Government, Colonel Eulogio Despujol surprises a Carlist force under Manuel Marco de Bello at Caspe, northeast of Alcañiz. In a brilliant action the Carlists are routed, losing 200 prisoners and 80 horses, while Despujol is promoted to Brigadier and becomes Conde de Caspe. * January 20 – The Pangkor Treaty (also known as the Pangkor Engagement), by which the British extended their control over first the Sultanate of Perak, and later the other independent Malay States, is signed. * January 23 **Alfred, Duke of Saxe-Coburg and Gotha, Prince Alfred, Duke of Edinburgh, second son of Queen Victoria, marries Grand Duchess Maria Alexandrovna of Russia, only daug ...
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