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Karel Wiesner
Karel František Wiesner (November 25, 1919 – November 28, 1986) was a Canadian chemist of Czech origin known for his contributions to the chemistry of natural products, notably aconitum alkaloids and digitalis glycosides. Early life and career He was born in Prague, Czechoslovakia, into a family of some wealth and notability. His undergraduate education began in 1938 when he enrolled to study natural sciences at Charles University. His studies were interrupted the following year when universities were shuttered under the German occupation. Working under the supervision of at Bulovka Hospital, and in a rudimentary laboratory in the basement of his parental home, he discovered a polarographic method of measuring fast chemical reactions. He was awarded a doctorate for this research when Charles University reopened in 1945. In 1943, he joined a research group at the Fragner pharmaceutical company near Prague that was working to develop a penicillin variant. Despite working ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fredericton
Fredericton (; ) is the capital city of the Canadian province of New Brunswick. The city is situated in the west-central portion of the province along the Saint John River, which flows west to east as it bisects the city. The river is the dominant natural feature of the area. One of the main urban centres in New Brunswick, the city had a population of 63,116 and a metropolitan population of 108,610 in the 2021 Canadian Census. It is the third-largest city in the province after Moncton and Saint John. An important cultural, artistic, and educational centre for the province, Fredericton is home to two universities, the New Brunswick College of Craft and Design, and cultural institutions such as the Beaverbrook Art Gallery, the Fredericton Region Museum, and The Playhouse, a performing arts venue. The city hosts the annual Harvest Jazz & Blues Festival, attracting regional and international jazz, blues, rock, and world artists. Fredericton is also an important and vibrant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bulovka Hospital
Bulovka Hospital ( cs, Fakultní nemocnice Bulovka) is a large teaching hospital complex in Prague, situated on a hillock adjoining the in Prague 8 - Libeň near the defunct homestead of Bulovka. The most striking building in the complex is the hospital's famous neo-Rococo building called . See also * Motol University Hospital Motol University Hospital ( cs, Fakultní nemocnice v Motole) is a large teaching hospital in the Motol area of Prague. It is the largest medical facility in the Czech Republic The Czech Republic, or simply Czechia, is a landlocked co ..., another major teaching hospital complex in Prague References External links * http://bulovka.cz/ * Hospitals in Prague Teaching hospitals 1931 establishments in Czechoslovakia {{CzechRepublic-struct-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diterpene
Diterpenes are a class of chemical compounds composed of four isoprene units, often with the molecular formula C20H32. They are biosynthesized by plants, animals and fungi via the HMG-CoA reductase pathway, with geranylgeranyl pyrophosphate being a primary intermediate. Diterpenes form the basis for biologically important compounds such as retinol, retinal, and phytol. They are known to be antimicrobial and antiinflammatory. Structures As with most terpenes a huge number of potential structures exists, which may be broadly divided according to the number of rings present. Biosynthesis Diterpenes are derived from the addition of one IPP unit to FPP to form geranylgeranyl-pyrophosphate (GGPP). From GGPP, structural diversity is achieved mainly by two classes of enzymes; the diterpene synthases and cytochromes P450. Several diterpenes are produced by plants and cyanobacteria. GGPP is also the precursor for the synthesis of the phytane by the action of the enzyme geranylger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spectroscopy
Spectroscopy is the field of study that measures and interprets the electromagnetic spectra that result from the interaction between electromagnetic radiation and matter as a function of the wavelength or frequency of the radiation. Matter waves and acoustic waves can also be considered forms of radiative energy, and recently gravitational waves have been associated with a spectral signature in the context of the Laser Interferometer Gravitational-Wave Observatory (LIGO) In simpler terms, spectroscopy is the precise study of color as generalized from visible light to all bands of the electromagnetic spectrum. Historically, spectroscopy originated as the study of the wavelength dependence of the absorption by gas phase matter of visible light dispersed by a prism. Spectroscopy, primarily in the electromagnetic spectrum, is a fundamental exploratory tool in the fields of astronomy, chemistry, materials science, and physics, allowing the composition, physical structure and e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Magnetic Resonance
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz). NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Cultural Council
The World Cultural Council is an international organization whose goals are to promote cultural values, goodwill and philanthropy among individuals. The organization founded in 1981 and based in Mexico, has held a yearly award ceremony since 1984 by granting the Albert Einstein World Award of Science, the José Vasconcelos World Award of Education, and the Leonardo da Vinci World Award of Arts to outstanding scientists, educators, and artists, who have contributed positively to the cultural enrichment of mankind. The members of the Council include several Nobel laureates. Founding members The founding members of the World Cultural Council are 124 distinguished personalities in such fields as the arts, biology, chemistry, physics, medicine, psychology, neuroscience, astronomy, oceanography, astrophysics, anthropology, and zoology. Some of these members are recipients of awards because of their outstanding achievements including the Nobel Prize, the National Medal of Science, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal
Montreal ( ; officially Montréal, ) is the List of the largest municipalities in Canada by population, second-most populous city in Canada and List of towns in Quebec, most populous city in the Provinces and territories of Canada, Canadian province of Quebec. Founded in 1642 as ''Fort Ville-Marie, Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-peaked hill around which the early city of Ville-Marie is built. The city is centred on the Island of Montreal, which obtained its name from the same origin as the city, and a few much smaller peripheral islands, the largest of which is Île Bizard. The city is east of the national capital Ottawa, and southwest of the provincial capital, Quebec City. As of 2021, the city had a population of 1,762,949, and a Census Metropolitan Area#Census metropolitan areas, metropolitan population of 4,291,732, making it the List of the largest municipalities in Canada by population, second-largest city, and List of cen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wyeth-Ayerst
Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in 2002. Its headquarters moved to Collegeville, Pennsylvania and Madison, New Jersey, before they were consolidated with Pfizer's in New York City after the 2009 merger. Most of Wyeth's pharmaceutical assets were acquired by Pfizer in 2009, while its infant and maternal nutrition business was acquired by Nestlé in 2012. Wyeth manufactured over-the-counter drugs (OTCs) Robitussin and the analgesic Advil (ibuprofen) as well as prescription drugs Premarin and Effexor. History 1860–1899 In 1860, pharmacists John (1834–1907) and Frank Wyeth opened a drugstore with a small research lab on Walnut Street in Philadelphia. In 1862, on the suggestion of doctors, they began to manufacture large quantities of commonly ordered medicines. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zürich
Zürich () is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zürich. It is located in north-central Switzerland, at the northwestern tip of Lake Zürich. As of January 2020, the municipality has 434,335 inhabitants, the Urban agglomeration, urban area 1.315 million (2009), and the Zürich metropolitan area 1.83 million (2011). Zürich is a hub for railways, roads, and air traffic. Both Zurich Airport and Zürich Hauptbahnhof, Zürich's main railway station are the largest and busiest in the country. Permanently settled for over 2,000 years, Zürich was founded by the Roman Empire, Romans, who called it '. However, early settlements have been found dating back more than 6,400 years (although this only indicates human presence in the area and not the presence of a town that early). During the Middle Ages, Zürich gained the independent and privileged status of imperial immediacy and, in 1519, became a primary centre of the Protestant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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