|
K. K. Chen
Ko Kuei Chen (; 26 February 1898 – 12 December 1988) was a Chinese-American scientist who led pharmacological research at Eli Lilly and Company for 34 years. He is known for his work with ephedrine, cyanide poisoning therapy, and toad venom steroids. He was elected an inaugural member of Academia Sinica in 1948 and awarded the Remington Medal in 1965 for excellence in pharmacy. Career Chen was born in 1898 in Jinze, Jiangsu, now a town in Shanghai. After studying at Tsinghua College in Beijing, he moved to the United States in 1918 to further his education, earning a BS in 1920 and a PhD in 1923 from the University of Wisconsin-Madison. In 1923 he returned to China to work with CF Schmidt at Peking Union Medical College studying the effects of ephedrine. Upon finishing this appointment, he returned to the States to complete his studies with an MD from Johns Hopkins University in 1927. He continued working at Johns Hopkins for a couple of years before accepting an offer in 19 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jinze
Jinze () is a town in Qingpu District of Shanghai, China. As of the 2017 census it had a population of 60,800 and an area of . The town is bordered by two provinces, namely Zhejiang and Jiangsu. With convenient land and water transportation, it is an important transport hub linking Shanghai, Zhejiang and Jiangsu. It is surrounded by the towns of Shenta, Zhouzhuang and Jinxi on the northwest, Liantang Town on the southeast, Zhujiajiao Town on the east, and the towns of Dingshan and Dashun on the southwest. Name Jinze, formerly known as "Bainingli" (). According to ''Chorography of Jiangnan'' (), the name derives from a farmer got a stone of the same colour as gold. History In 978, it used to be in the territory of Song dynasty, Northern Song Empire (960–1127) under the jurisdiction of Huating County (). In 1279, the Yuan dynasty, Yuan Empire (1271–1368) set up province system to maintain control of the vast region. Jinze under the jurisdiction of Songjiang Prefecture () ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacological
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phi Beta Kappa
The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, and to induct the most outstanding students of arts and sciences at only select American colleges and universities. It was founded at the College of William and Mary on December 5, 1776, as the first collegiate Greek-letter fraternity and was among the earliest collegiate fraternal societies. Since its inception, 17 U.S. Presidents, 40 U.S. Supreme Court Justices, and 136 Nobel Laureates have been inducted members. Phi Beta Kappa () stands for ('), which means "Wisdom it. love of knowledgeis the guide it. helmsmanof life". Membership Phi Beta Kappa has chapters in only about 10% of American higher learning institutions, and only about 10% of these schools' Arts and Sciences graduates are invited to join the society. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ROTC
The Reserve Officers' Training Corps (ROTC ( or )) is a group of college- and university-based officer-training programs for training commissioned officers of the United States Armed Forces. Overview While ROTC graduate officers serve in all branches of the U.S. military, the U.S. Marine Corps, the U.S. Space Force, and the U.S. Coast Guard do not have their own respective ROTC programs; rather, graduates of Naval ROTC programs have the option to serve as officers in the Marine Corps contingent on meeting Marine Corps requirements. In 2020, ROTC graduates constituted 70 percent of newly commissioned active-duty U.S. Army officers, 83 percent of newly commissioned U.S. Marine Corps officers (through NROTC), 61 percent of newly commissioned U.S. Navy officers and 63 percent of newly commissioned U.S. Air Force officers, for a combined 56 percent of all active-duty officers in the Department of Defense commissioned that year. Under ROTC, a student may receive a competitive, mer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuba
The tuba (; ) is the lowest-pitched musical instrument in the brass family. As with all brass instruments, the sound is produced by lip vibrationa buzzinto a mouthpiece. It first appeared in the mid-19th century, making it one of the newer instruments in the modern orchestra and concert band. The tuba largely replaced the ophicleide. ''Tuba'' is Latin for "trumpet". A person who plays the tuba is called a tubaist, a tubist, or simply a tuba player. In a British brass band or military band, they are known as bass players. History Prussian Patent No. 19 was granted to Wilhelm Friedrich Wieprecht and Johann Gottfried Moritz (1777–1840) on September 12, 1835 for a "bass tuba" in F1. The original Wieprecht and Moritz instrument used five valves of the Berlinerpumpen type that were the forerunners of the modern piston valve. The first tenor tuba was invented in 1838 by Carl Wilhelm Moritz (1810–1855), son of Johann Gottfried Moritz. The addition of valves made it po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Confucius
Confucius ( ; zh, s=, p=Kǒng Fūzǐ, "Master Kǒng"; or commonly zh, s=, p=Kǒngzǐ, labels=no; – ) was a Chinese philosopher and politician of the Spring and Autumn period who is traditionally considered the paragon of Chinese sages. Confucius's teachings and philosophy underpin East Asian culture and society, remaining influential across China and East Asia to this day. Confucius considered himself a transmitter for the values of earlier periods which he claimed had been abandoned in his time. His philosophical teachings, called Confucianism, emphasized personal and governmental morality, correctness of social relationships, justice, kindness, and sincerity. His followers competed with many other schools during the Hundred Schools of Thought era, only to be suppressed in favor of the Legalists during the Qin dynasty. After the collapse of Qin and the victory of Han over Chu, Confucius's thoughts received official sanction in the new government. During the Tan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toad Venom Steroids
Toad is a common name for certain frogs, especially of the family Bufonidae, that are characterized by dry, leathery skin, short legs, and large bumps covering the parotoid glands. A distinction between frogs and toads is not made in scientific taxonomy, but is common in popular culture ( folk taxonomy), in which toads are associated with drier, rougher skin and more terrestrial habitats. List of toad families In scientific taxonomy, toads include the true toads (Bufonidae) and various other terrestrial or warty-skinned frogs. Non-bufonid "toads" can be found in the families: * Bombinatoridae (fire-bellied toads and jungle toads) * Calyptocephalellidae ( helmeted water toad and false toads) * Discoglossidae ( midwife toads) * Myobatrachidae (Australian toadlets) * Pelobatidae (European spadefoot toad) * Rhinophrynidae ( burrowing toads) * Scaphiopodidae (American spadefoot toads) * Microhylidae ( narrowmouth toads) Biology Usually the largest of the bumps on the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycosides
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of ''Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an ''O-glycoside''), N- (a ''glycosylamine''), S-(a ''thioglycoside''), or C- (a '' C-glycoside'') glycosidic bond. According to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyanide Poisoning
Cyanide poisoning is poisoning that results from exposure to any of a number of forms of cyanide. Early symptoms include headache, dizziness, fast heart rate, shortness of breath, and vomiting. This phase may then be followed by seizures, slow heart rate, low blood pressure, loss of consciousness, and cardiac arrest. Onset of symptoms usually occurs within a few minutes. Some survivors have long-term neurological problems. Toxic cyanide-containing compounds include hydrogen cyanide gas and a number of cyanide salts. Poisoning is relatively common following breathing in smoke from a house fire. Other potential routes of exposure include workplaces involved in metal polishing, certain insecticides, the medication sodium nitroprusside, and certain seeds such as those of apples and apricots. Liquid forms of cyanide can be absorbed through the skin. Cyanide ions interfere with cellular respiration, resulting in the body's tissues being unable to use oxygen. Diagnosis is often diffi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whooping Cough
Whooping cough, also known as pertussis or the 100-day cough, is a highly contagious bacterial disease. Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. Following a fit of coughing, a high-pitched whoop sound or gasp may occur as the person breathes in. The violent coughing may last for 10 or more weeks, hence the phrase "100-day cough". A person may cough so hard that they vomit, break ribs, or become very tired from the effort. Children less than one year old may have little or no cough and instead have periods where they cannot breathe. The time between infection and the onset of symptoms is usually seven to ten days. Disease may occur in those who have been vaccinated, but symptoms are typically milder. Pertussis is caused by the bacterium ''Bordetella pertussis''. It is spread easily through the coughs and sneezes of an infected person. Peopl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hay Fever
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of pollen exposure. Many people with allergic rhinitis also have asthma, allergic conjunctivitis, or atopic dermatitis. Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics and environmental exposures contribute to the development of allergies. Growing up on a farm and having multiple siblings decreases this risk. The underlying mechanism involves IgE antibodie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
