John Sappington
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John Sappington
John S. Sappington (1776-1856) was an American physician known for developing a quinine pill to treat malarial and other fever diseases in the Missouri and Mississippi valleys, where the disease was widespread. He later used the pill to prevent malaria. Because he both manufactured and sold "Dr. Sappington's Anti-Fever Pills", he became wealthy from his bestseller. From Maryland and Tennessee, Sappington settled in Missouri after completing medical training and getting married. He married Jane Breathitt, a sister of future Kentucky governor John Breathitt and two other politically connected brothers. As an early pioneer near Arrow Rock, Missouri, Sappington established several businesses to earn money to acquire land. He eventually acquired thousands of acres and became a major planter and slaveholder in the state. In furtherance of his work on treating malarial fever, he wrote ''The Theory and Treatment of Fevers,'' (1844), the first medical book printed in Missouri and among the ...
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Portrait Of John Sappington
A portrait is a painting, photograph, sculpture, or other artistic representation of a person, in which the face and its expressions are predominant. The intent is to display the likeness, personality, and even the mood of the person. For this reason, in photography a portrait is generally not a snapshot, but a composed image of a person in a still position. A portrait often shows a person looking directly at the painter or photographer, in order to most successfully engage the subject with the viewer. History Prehistorical portraiture Plastered human skulls were reconstructed human skulls that were made in the ancient Levant between 9000 and 6000 BC in the Pre-Pottery Neolithic B period. They represent some of the oldest forms of art in the Middle East and demonstrate that the prehistoric population took great care in burying their ancestors below their homes. The skulls denote some of the earliest sculptural examples of portraiture in the history of art. Historical portraitur ...
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Saline County, Missouri
Saline County is located along the Missouri River in the U.S. state of Missouri. As of the 2010 census, the population was 23,370. Its county seat is Marshall. The county was established November 25, 1820, and named for the region's salt springs. Settled primarily by migrants from the Upper South during the nineteenth century, this county was in the region bordering the Missouri River known as " Little Dixie". In the antebellum years, it had many plantations operated with the forced labor of enslaved workers. One-third of the county population was African American at the start of the American Civil War, but their proportion of the residents has declined dramatically to little more than five percent. Saline County comprises the Marshall, Missouri Micropolitan Statistical Area. History Saline County was occupied for thousands of years by succeeding cultures of Missouri Native Americans. Saline County was organized by European-American settlers on November 25, 1820, and was n ...
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Claiborne Fox Jackson
Claiborne Fox Jackson (April 4, 1806 – December 6, 1862) was an American politician of the Democratic Party in Missouri. He was elected as the 15th Governor of Missouri, serving from January 3, 1861, until July 31, 1861, when he was forced out by the Unionist majority in the legislature, after planning to force secession of the state. Before the war, Jackson worked with his father-in-law, John Sappington, to manufacture and sell patent medicines, in the form of quinine pills, to treat and prevent malaria. He became quite wealthy and politically influential, deeply involved in the Democratic party in Saline County and central Missouri. He served twelve years in the Missouri House of Representatives, twice as Speaker. In 1848 he was elected to the State Senate. To win votes in the 1860 election, Jackson claimed to be anti-secession, but he was secretly planning a secessionist coup in league with Confederate President Jefferson Davis. Nathaniel Lyon, Union commander of t ...
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Meredith Miles Marmaduke
Meredith Miles Marmaduke (August 28, 1791 – March 26, 1864) was an American politician who served as the 8th governor of Missouri in 1844, to fill out the term of Governor Thomas Reynolds, who had committed suicide. A member of the Democratic Party, he had been elected and served as the 6th lieutenant governor. Marmaduke had a large family. He had married well, to Lavinia, a daughter of Dr. John Sappington, a pioneering physician in Saline County, Missouri, and his wife Jane, sister of a Kentucky governor. The two men were affiliated in Sappington's business for a time, working with traders on the Santa Fe Trail. Marmaduke later acquired and operated a successful plantation in Saline County, becoming a large slaveholder as well. He and his wife reared their ten children here. Marmaduke changed his opinions and developed Unionist leanings by mid-century, but four of his sons served the Confederacy during the American Civil War, and two died. His son John Sappington Ma ...
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Mercury(I) Chloride
Mercury(I) chloride is the chemical compound with the formula Hg2Cl2. Also known as the mineral calomel (a rare mineral) or mercurous chloride, this dense white or yellowish-white, odorless solid is the principal example of a mercury(I) compound. It is a component of reference electrodes in electrochemistry. History The name calomel is thought to come from the Greek ''καλός'' "beautiful", and ''μέλας'' "black"; or ''καλός'' and ''μέλι'' "honey" from its sweet taste. The "black" name (somewhat surprising for a white compound) is probably due to its characteristic disproportionation reaction with ammonia, which gives a spectacular black coloration due to the finely dispersed metallic mercury formed. It is also referred to as the mineral ''horn quicksilver'' or ''horn mercury''. Calomel was taken internally and used as a laxative, for example to treat George III in 1801, and disinfectant, as well as in the treatment of syphilis, until the early 20th century. Unti ...
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Bloodletting
Bloodletting (or blood-letting) is the withdrawal of blood from a patient to prevent or cure illness and disease. Bloodletting, whether by a physician or by leeches, was based on an ancient system of medicine in which blood and other bodily fluids were regarded as "Humorism, humours" that had to remain in proper balance to maintain health. It is claimed to have been the most common medical practice performed by surgeons from Ancient history, antiquity until the late 19th century, a span of over 2,000 years. In Europe, the practice continued to be relatively common until the end of the 19th century.B.) Anderson, Julie, Emm Barnes, and Enna Shackleton. "The Art of Medicine: Over 2,000 Years of Images and Imagination [Hardcover]." The Art of Medicine: Over 2, 000 Years of Images and Imagination: Julie Anderson, Emm Barnes, Emma Shackleton: : The Ilex Press Limited, 2013. The practice has now been abandoned by modern-style medicine for all except a few very specific medical ...
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Influenza
Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus (typically two days) and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus, termed influenza viruses A, B, C, and D. Aquatic birds are the primary source of Influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and Influenza C virus (ICV) pri ...
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Yellow Fever
Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin. If this occurs, the risk of bleeding and kidney problems is increased. The disease is caused by the yellow fever virus and is spread by the bite of an infected mosquito. It infects humans, other primates, and several types of mosquitoes. In cities, it is spread primarily by ''Aedes aegypti'', a type of mosquito found throughout the tropics and subtropics. The virus is an RNA virus of the genus ''Flavivirus''. The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood-sample testing with polymerase chain reaction is required. A saf ...
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Scarlet Fever
Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects children between five and 15 years of age. The signs and symptoms include a sore throat, fever, headache, swollen lymph nodes, and a characteristic rash. The face is flushed and the rash is red and blanching. It typically feels like sandpaper and the tongue may be red and bumpy. The rash occurs as a result of capillary damage by exotoxins produced by ''S.pyogenes''. On darker pigmented skin the rash may be hard to discern. Scarlet fever affects a small number of people who have strep throat or streptococcal skin infections. The bacteria are usually spread by people coughing or sneezing. It can also be spread when a person touches an object that has the bacteria on it and then touches their mouth or nose. The diagnosis is typically confirmed by ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ...
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Quechua People
Quechua people (, ; ) or Quichua people, may refer to any of the aboriginal people of South America who speak the Quechua languages, which originated among the Indigenous people of Peru. Although most Quechua speakers are native to Peru, there are some significant populations in Ecuador, Bolivia, Chile, Colombia, and Argentina. The most common Quechua dialect is Southern Quechua. The Kichwa people of Ecuador speak the Kichwa dialect; in Colombia, the Inga people speak Inga Kichwa. The Quechua word for a Quechua speaker is ''runa'' or ''nuna'' ("person"); the plural is ''runakuna'' or ''nunakuna'' ("people"). "Quechua speakers call themselves Runa -- simply translated, 'the people.'" Some historical Quechua people are: * The Chanka people, who lived in the Huancavelica, Ayacucho, and Apurímac regions of Peru. * The Huanca people of the Junín Region of Peru, who spoke Quechua before the Incas did. * The Inca, who established the largest empire of the pre-Columbian era. * T ...
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Lima
Lima ( ; ), originally founded as Ciudad de Los Reyes (City of The Kings) is the capital and the largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rivers, in the desert zone of the central coastal part of the country, overlooking the Pacific Ocean. Together with the seaside city of Callao, it forms a contiguous urban area known as the Lima Metropolitan Area. With a population of more than 9.7 million in its urban area and more than 10.7 million in its metropolitan area, Lima is one of the largest cities in the Americas. Lima was named by natives in the agricultural region known by native Peruvians as ''Limaq''. It became the capital and most important city in the Viceroyalty of Peru. Following the Peruvian War of Independence, it became the capital of the Republic of Peru (República del Perú). Around one-third of the national population now lives in its Lima Metropolitan Area, metropolitan area. The city of Li ...
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