Johannes Fibiger
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Johannes Fibiger
Johannes Andreas Grib Fibiger (23 April 1867 – 30 January 1928) was a Danish physician and professor of anatomical pathology at the University of Copenhagen. He was the recipient of the 1926 Nobel Prize in Physiology or Medicine "for his discovery of the ''Spiroptera carcinoma''". He demonstrated that the roundworm which he called ''Spiroptera carcinoma'' (but correctly named '' Gongylonema neoplasticum'') could cause stomach cancer (squamous cell carcinoma) in rats and mice. His experimental results were later proven to be a case of mistaken conclusion. Erling Norrby, who had served as the Permanent Secretary of the Royal Swedish Academy of Sciences and Professor and Chairman of Virology at the Karolinska Institute, declared Fibiger's Nobel Prize as "one of the biggest blunders made by the Karolinska Institute." While working at the Institute of Pathological Anatomy of University of Copenhagen, Fibiger discovered new roundworms in 1907 from wild rats. He suspected that the ro ...
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Silkeborg
Silkeborg () is a Danish town with a population of 49,747 (1 January 2022).BY3: Population 1. January by urban areas, area and population density
The Mobile Statbank from Statistics Denmark
Silkeborg is the seat of Silkeborg City Council (with 92,024 inhabitants as of 2018). Silkeborg is located in the middle of the ic peninsula, slightly west of the geographical centre of

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Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ...
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Royal Danish Academy Of Sciences And Letters
{{Infobox organization , name = The Royal Danish Academy of Sciences and Letters , full_name = , native_name = Det Kongelige Danske Videnskabernes Selskab , native_name_lang = , logo = Royal Danish Academy of Sciences and Letters seal.svg , logo_size = 150 , logo_alt = , logo_caption = , image = Carlsbergfondet.JPG , image_size = , alt = , caption = The building on H.C. Andersens Boulevard. , map = , map_size = , map_alt = , map_caption = , map2 = , map2_size = , map2_alt = , map2_caption = , abbreviation = , nickname = , pronounce = , pronounce ref = , pronounce comment = , pronounce 2 = , named_after = , motto = , predecessor = , merged ...
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Metastatic
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells known as circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels, after which they are able ...
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Papilloma
A papilloma (plural papillomas or papillomata) ('' papillo-'' + '' -oma'') is a benign epithelial tumor growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple). When used without context, it frequently refers to infections (squamous cell papilloma) caused by human papillomavirus (HPV), such as warts. Human papillomavirus infection is a major cause of cervical cancer, vulvar cancer, vaginal cancer, penis cancer, anal cancer, and HPV-positive oropharyngeal cancers. Most viral warts are caused by human papillomavirus infection (HPV), of which there are nearly 200 distinct human papillomaviruses (HPVs), and many HPV types are carcinogenic. There are, however, a number of other conditions that cause papilloma, as well as many cases in which there is no known cause. Signs and symptoms A benign papillomatous tumor is ...
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Tartu
Tartu is the second largest city in Estonia after the Northern European country's political and financial capital, Tallinn. Tartu has a population of 91,407 (as of 2021). It is southeast of Tallinn and 245 kilometres (152 miles) northeast of Riga, Latvia. Tartu lies on the Emajõgi river, which connects the two largest lakes in Estonia, Lake Võrtsjärv and Lake Peipus. From the 13th century until the end of the 19th century, Tartu was known in most of the world by variants of its historical name Dorpat. Tartu, the largest urban centre of southern Estonia, is often considered the "intellectual capital city" of the country, especially as it is home to the nation's oldest and most renowned university, the University of Tartu (founded in 1632). Tartu also houses the Supreme Court of Estonia, the Ministry of Education and Research, the Estonian National Museum, and the oldest Estonian-language theatre, Vanemuine. It is also the birthplace of the Estonian Song Festivals. Tar ...
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Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially m ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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The British Medical Journal
''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Originally called the ''British Medical Journal'', the title was officially shortened to ''BMJ'' in 1988, and then changed to ''The BMJ'' in 2014. The journal is published by BMJ Publishing Group Ltd, a subsidiary of the British Medical Association (BMA). The editor-in-chief of ''The BMJ'' is Kamran Abbasi, who was appointed in January 2022. History The journal began publishing on 3 October 1840 as the ''Provincial Medical and Surgical Journal'' and quickly attracted the attention of physicians around the world through its publication of high-impact original research articles and unique case reports. The ''BMJ''s first editors were P. Hennis Green, lecturer on the diseases of children at the Hunterian School of Medicine, who also was its founde ...
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Corynebacterium Diphtheriae
''Corynebacterium diphtheriae'' is the pathogenic bacterium that causes diphtheria. It is also known as the Klebs–Löffler bacillus, because it was discovered in 1884 by German bacteriologists Edwin Klebs (1834–1912) and Friedrich Löffler (1852–1915). The bacteria are usually harmless unless they are infected by a bacteriophage that carries a gene that gives rise to a toxin. This toxin causes the disease. Diphtheria is caused by the adhesion and infiltration of the bacteria into the mucosal layers of the body, primarily affecting the respiratory tract and the subsequent release of an endotoxin. The toxin has a localized effect on skin lesions, as well as a metastatic, proteolytic effects on other organ systems in severe infections. Originally a major cause of childhood mortality, diphtheria has been almost entirely eradicated due to the vigorous administration of the diphtheria vaccination in the 1910s. Diphtheria is no longer transmitted as frequently due to the d ...
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Cardiac Arrest
Cardiac arrest is when the heart suddenly and unexpectedly stops beating. It is a medical emergency that, without immediate medical intervention, will result in sudden cardiac death within minutes. Cardiopulmonary resuscitation (CPR) and possibly defibrillation are needed until further treatment can be provided. Cardiac arrest results in a rapid loss of consciousness, and breathing may be abnormal or absent. While cardiac arrest may be caused by heart attack or heart failure, these are not the same, and in 15 to 25% of cases, there is a non-cardiac cause. Some individuals may experience chest pain, shortness of breath, nausea, an elevated heart rate, and a light-headed feeling immediately before entering cardiac arrest. The most common cause of cardiac arrest is an underlying heart problem like coronary artery disease that decreases the amount of oxygenated blood supplying the heart muscle. This, in turn, damages the structure of the muscle, which can alter its function. ...
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Prosector
A prosector is a person with the special task of preparing a dissection for demonstration, usually in medical schools or hospitals. Many important anatomists began their careers as prosectors working for lecturers and demonstrators in anatomy and pathology. The act of prosecting differs from that of dissecting. A prosection is a professionally prepared dissection prepared by a prosector – a person who is well versed in anatomy and who therefore prepares a specimen so that others may study and learn anatomy from it. A dissection is prepared by a student who is dissecting the specimen for the purpose of learning more about the anatomical structures pertaining to that specimen. The term dissection may also be used to describe the act of cutting. Therefore, a prosector dissects to prepare a prosection. Prosecting is intricate work where numerous tools are used to produce a desired specimen. Scalpels and scissors allow for sharp dissection where tissue is cut, e.g. the biceps brachii ...
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