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Johann Frederik Eijkman
Johan Fredrik Eykman or Johann Frederik Eijkman (19 January 1851 – 7 January 1915) was a Dutch chemist. Family background He is one of the eight children of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His brother Christiaan Eijkman (1858–1930) was a physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of vitamins. Together with Sir Frederick Hopkins, his brother received the Nobel Prize for Physiology or Medicine. Life in Japan He was hired during the Meiji period, a Japanese era which extended from September 1868 through July 1912. During his stay in Japan, he was the first to isolate shikimic acid in 1885 from the Japanese flower shikimi (シキミ, the Japanese star anise ''Illicium anisatum'', with common names Japanese star anise, Aniseed tree, and sacred Anise tree, known in Japan as , is a tree closely related to the Chinese star anise (''Illicium verum)''. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nijkerk
Nijkerk (; Dutch Low Saxon: ''Niekark'') is a municipality and a city located in the middle of the Netherlands, in the province of Gelderland. Population centres Some people state that ''Groot Corlaer'' is a population centre on its own, but it is officially part of Nijkerk. Transportation Railway station: Nijkerk The city of Nijkerk The name Nijkerk stems from Nieuwe Kerk (Dutch for New Church). This new church was built after the old chapel had been destroyed by fire in 1221. Nijkerk was strategically located between the Duchy of Guelders ''(Dutch: Hertogdom Gelre)'' and the Bishopric of Utrecht. Because of this strategic location Nijkerk regularly was the scene of war, and in 1412 the village was completely destroyed. It was restored and Nijkerk received city rights in 1413. In 1421 the church that gave Nijkerk its name burnt down and was replaced; this happened several times, until a new church, the ''Grote-of-Sint-Catharinakerk''; was built in the 18th century. It sti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Groningen
Groningen (; gos, Grunn or ) is the capital city and main municipality of Groningen province in the Netherlands. The ''capital of the north'', Groningen is the largest place as well as the economic and cultural centre of the northern part of the country; as of December 2021, it had 235,287 inhabitants, making it the sixth largest city/municipality of the Netherlands and the second largest outside the Randstad. Groningen was established more than 950 years ago and gained city rights in 1245. Due to its relatively isolated location from the then successive Dutch centres of power (Utrecht, The Hague, Brussels), Groningen was historically reliant on itself and nearby regions. As a Hanseatic city, it was part of the North German trade network, but later it mainly became a regional market centre. At the height of its power in the 15th century, Groningen could be considered an independent city-state and it remained autonomous until the French era. Today Groningen is a university ci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christiaan Eijkman
Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with Sir Frederick Hopkins, he received the Nobel Prize for Physiology or Medicine in 1929 for the discovery of vitamins. Biography Early life and education Christiaan Eijkman was born on 11 August 1858, at Nijkerk, Netherlands as the seventh child of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His elder brother Johann Frederik Eijkman (1851–1915) was also a chemist. A year later, in 1859, the Eijkman family moved to Zaandam, where his father was appointed head of a newly founded school for advanced elementary education. It was here that Christiaan and his brothers received their early education. In 1875, after taking his preliminary examinations, Eijkman became a student at the Military Medical School of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meiji Period
The is an era of Japanese history that extended from October 23, 1868 to July 30, 1912. The Meiji era was the first half of the Empire of Japan, when the Japanese people moved from being an isolated feudal society at risk of colonization by Western powers to the new paradigm of a modern, industrialized nation state and emergent great power, influenced by Western scientific, technological, philosophical, political, legal, and aesthetic ideas. As a result of such wholesale adoption of radically different ideas, the changes to Japan were profound, and affected its social structure, internal politics, economy, military, and foreign relations. The period corresponded to the reign of Emperor Meiji. It was preceded by the Keiō era and was succeeded by the Taishō era, upon the accession of Emperor Taishō. The rapid modernization during the Meiji era was not without its opponents, as the rapid changes to society caused many disaffected traditionalists from the former samurai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shikimic Acid
Shikimic acid, more commonly known as its anionic form shikimate, is a cyclohexene, a cyclitol and a cyclohexanecarboxylic acid. It is an important biochemical metabolite in plants and microorganisms. Its name comes from the Japanese flower ''shikimi'' (, the Japanese star anise, ''Illicium anisatum''), from which it was first isolated in 1885 by Johan Fredrik Eykman. The elucidation of its structure was made nearly 50 years later. Biosynthesis Phosphoenolpyruvate and erythrose-4-phosphate condense to form 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP), in a reaction catalyzed by the enzyme DAHP synthase. DAHP is then transformed to 3-dehydroquinate (DHQ), in a reaction catalyzed by DHQ synthase. Although this reaction requires nicotinamide adenine dinucleotide (NAD) as a cofactor, the enzymic mechanism regenerates it, resulting in the net use of no NAD. : DHQ is dehydrated to 3-dehydroshikimic acid by the enzyme 3-dehydroquinate dehydratase, which is reduced to shiki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Japanese Star Anise
''Illicium anisatum'', with common names Japanese star anise, Aniseed tree, and sacred Anise tree, known in Japan as , is a tree closely related to the Chinese star anise (''Illicium verum)''. Since it is highly toxic, the fruit is not edible; instead, the dried and powdered leaves are burned as incense in Japan. Its branches and evergreen leaves are considered highly sacred by Japanese Buddhists due to aversion from insects and their ability to remain fresh after pruning. ''Illicium anisatum'' is native to Japan. It is similar to the Chinese star anise, but its fruit is smaller and with a weaker odour, reputed to be more similar to the aroma of cardamom than to that of anise. Due to its poisonous nature, its seeds have been used as a fish poison as well as a natural agricultural pesticide and to repel animals from digging the grounds of Japanese graveyards. Its seeds have also been used medicinally to treat toothache and dermatitis topically, since it is unsuitable for int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1851 Births
Events January–March * January 11 – Hong Xiuquan officially begins the Taiping Rebellion. * January 15 – Christian Female College, modern-day Columbia College, receives its charter from the Missouri General Assembly. * January 23 – The flip of a coin, subsequently named Portland Penny, determines whether a new city in the Oregon Territory is named after Boston, Massachusetts, or Portland, Maine, with Portland winning. * January 28 – Northwestern University is founded in Illinois. * February 1 – ''Brandtaucher'', the oldest surviving submersible craft, sinks during acceptance trials in the German port of Kiel, but the designer, Wilhelm Bauer, and the two crew escape successfully. * February 6 – Black Thursday in Australia: Bushfires sweep across the state of Victoria, burning about a quarter of its area. * February 12 – Edward Hargraves claims to have found gold in Australia. * February 15 – In Boston, Massachusetts, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1915 Deaths
Events Below, the events of World War I have the "WWI" prefix. January *January – British physicist Sir Joseph Larmor publishes his observations on "The Influence of Local Atmospheric Cooling on Astronomical Refraction". *January 1 ** WWI: British Royal Navy battleship HMS ''Formidable'' is sunk off Lyme Regis, Dorset, England, by an Imperial German Navy U-boat, with the loss of 547 crew. ** Battle of Broken Hill: A train ambush near Broken Hill, New South Wales, Australia, is carried out by two men (claiming to be in support of the Ottoman Empire) who are killed, together with 4 civilians. * January 5 – Joseph E. Carberry sets an altitude record of , carrying Capt. Benjamin Delahauf Foulois as a passenger, in a fixed-wing aircraft. * January 12 ** The United States House of Representatives rejects a proposal to give women the right to vote. ** '' A Fool There Was'' premières in the United States, starring Theda Bara as a ''femme fatale''; she quickly becomes one o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Nijkerk
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of The University Of Amsterdam
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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