Jean Delay
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Jean Delay
Jean Delay (14 November 1907, Bayonne – 29 May 1987, Paris) was a French psychiatrist, neurologist, writer, and a member of the Académie française (Chair 17). His assistant Pierre Deniker conducted a test of chlorpromazine on the male mental ward where Delay worked, and the two published their findings (quickly, with what has been called academic gamesmanship) in 1952. Chlorpromazine turned out to be the first effective drug treatment for mental illness and it had a profound effect on the mentally ill and mental asylums. In 1968–1970, student revolutionaries attacked his offices, and Delay was forced into retirement from medicine. In later life, he lived as a writer. Family and education The son of Maurice Delay, a successful surgeon and mayor of Bayonne, at age fourteen Delay earned a baccalaureate in philosophy. He studied medicine in Paris. After studying in hospitals for twenty years, especially the teaching of Pierre Janet and Georges Dumas, he turned to psychiatry. ...
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Bayonne
Bayonne (; eu, Baiona ; oc, label= Gascon, Baiona ; es, Bayona) is a city in Southwestern France near the Spanish border. It is a commune and one of two subprefectures in the Pyrénées-Atlantiques department, in the Nouvelle-Aquitaine region. Bayonne is located at the confluence of the Nive and Adour rivers in the northern part of the cultural region of the Basque Country. It is the seat of the Communauté d'agglomération du Pays Basque which roughly encompasses the western half of Pyrénées-Atlantiques, including the coastal city of Biarritz. This area also constitutes the southern part of Gascony, where the Aquitaine Basin joins the beginning of the Pre-Pyrenees. Together with nearby Anglet, Biarritz, Saint-Jean-de-Luz, as well as several smaller communes, Bayonne forms an urban area with 273,137 inhabitants at the 2018 census; 51,411 residents lived in the commune of Bayonne proper.
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Neurology
Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic research, basic or translational research. While neurology is a nonsurgical sp ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months (DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2 ...
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Neuroleptic
Antipsychotics, also known as neuroleptics, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. They are also the mainstay together with mood stabilizers in the treatment of bipolar disorder. Prior research has shown that use of any antipsychotic is associated with smaller brain tissue volumes, including white matter reduction and that this brain shrinkage is dose dependent and time dependent. A more recent controlled trial suggests that second generation antipsychotics combined with intensive psychosocial therapy may potentially prevent pallidal brain volume loss in first episode psychosis. The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such ...
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Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis it is often used by itself. It may also be used for atypical types of mycobacteria, such as '' M. avium'', '' M. kansasii'', and '' M. xenopi''. It is usually taken by mouth but may be used by injection into muscle. Common side effects include increased blood levels of liver enzymes and numbness in the hands and feet. Serious side effects may include liver inflammation and acute liver failure. It is unclear if use during pregnancy is safe for the baby. Use during breastfeeding is likely safe. Pyridoxine may be given to reduce the risk of side effects. Isoniazid works in part by disrupting the formation of the bacteria's cell wall which results in cell death. Isoniazid was first made in 1952. It is on the World ...
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Hierarchy
A hierarchy (from Greek: , from , 'president of sacred rites') is an arrangement of items (objects, names, values, categories, etc.) that are represented as being "above", "below", or "at the same level as" one another. Hierarchy is an important concept in a wide variety of fields, such as architecture, philosophy, design, mathematics, computer science, organizational theory, systems theory, systematic biology, and the social sciences (especially political philosophy). A hierarchy can link entities either directly or indirectly, and either vertically or diagonally. The only direct links in a hierarchy, insofar as they are hierarchical, are to one's immediate superior or to one of one's subordinates, although a system that is largely hierarchical can also incorporate alternative hierarchies. Hierarchical links can extend "vertically" upwards or downwards via multiple links in the same direction, following a path. All parts of the hierarchy that are not linked vertically to one ano ...
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Psilocybin
Psilocybin ( , ) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi. The most potent are members of the genus ''Psilocybe'', such as '' P. azurescens'', '' P. semilanceata'', and '' P. cyanescens'', but psilocybin has also been isolated from about a dozen other genera. Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks. Imagery found on prehistoric murals and rock paintings of modern-day Spain and Algeria suggests that human usage of psilocybin mushrooms predates recorded history. In Mesoamerica, the mushrooms had long been consumed in spiritual and div ...
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Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sources It occurs naturally in several species of cacti. It is also found in small amounts in certain members of the bean family, Fabaceae, including ''Acacia berlandieri''. However those claims concerning ''Acacia'' species have been challenged and have been unsupported in any additional analysis. History and use Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador. While religious and ceremonial peyote use was widespread in the Aztec empire and northern M ...
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World Congress Of Psychiatry
The World Psychiatric Association is an international umbrella organisation of psychiatric societies. Objectives and goals Originally created to produce world psychiatric congresses, it has evolved to hold regional meetings, to promote professional education and to set ethical, scientific and treatment standards for psychiatry. History Jean Delay was the first president of the Association for the Organization of World Congresses of Psychiatry when it was started in 1950. Donald Ewen Cameron became president of the World Psychiatric Association at its formal founding in 1961. In February 1983, the Soviet All-Union Society of Neurologists and Psychiatrists resigned from the World Psychiatric Association. This resignation occurred as a preemptive action amid a movement to expel the Soviet body from the global organization due to political abuse of psychiatry in the Soviet Union. The Soviet body was conditionally readmitted into the World Psychiatric Association in 1989, followi ...
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Rudolf Hess
Rudolf Walter Richard Hess (Heß in German; 26 April 1894 – 17 August 1987) was a German politician and a leading member of the Nazi Party in Nazi Germany. Appointed Deputy Führer to Adolf Hitler in 1933, Hess held that position until 1941, when he flew solo to Scotland in an attempt to negotiate the United Kingdom's exit from the Second World War. He was taken prisoner and eventually convicted of crimes against peace. He was still serving his life sentence at the time of his suicide in 1987. Hess enlisted as an infantryman in the Imperial German Army at the outbreak of World War I. He was wounded several times during the war and was awarded the Iron Cross, 2nd Class, in 1915. Shortly before the war ended, Hess enrolled to train as an aviator, but he saw no action in that role. He left the armed forces in December 1918 with the rank of . In 1919, Hess enrolled in the University of Munich, where he studied geopolitics under Karl Haushofer, a proponent of the concept ...
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World Psychiatric Association
The World Psychiatric Association is an international umbrella organisation of psychiatric societies. Objectives and goals Originally created to produce world psychiatric congresses, it has evolved to hold regional meetings, to promote professional education and to set ethical, scientific and treatment standards for psychiatry. History Jean Delay was the first president of the Association for the Organization of World Congresses of Psychiatry when it was started in 1950. Donald Ewen Cameron became president of the World Psychiatric Association at its formal founding in 1961. In February 1983, the Soviet All-Union Society of Neurologists and Psychiatrists resigned from the World Psychiatric Association. This resignation occurred as a preemptive action amid a movement to expel the Soviet body from the global organization due to political abuse of psychiatry in the Soviet Union. The Soviet body was conditionally readmitted into the World Psychiatric Association in 1989, follow ...
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Entrée Hôpital Sainte-Anne, Rue Cabanis
An entrée (, ; ) in modern French table service and that of much of the English-speaking world (apart from the United States and parts of Canada) is a dish served before the main course of a meal. Outside North America, it is generally synonymous with the terms ''hors d'oeuvre'', appetizer, or starter. It may be the first dish served, or it may follow a soup or other small dish or dishes. In the United States and parts of Canada, the term ''entrée'' refers to the main dish or the only dish of a meal. Early use of the term The word ''entrée'' as a culinary term first appears in print around 1536, in the ''Petit traicté auquel verrez la maniere de faire cuisine'', in a collection of menus at the end of the book. There, the first stage of each meal is called the ''entree de table'' (entrance to the table); the second stage consists of '' potaiges'' (foods boiled or simmered "in pots"); the third consists of one or more ''services de rost'' (meat or fowl "roasted" in dry heat) ...
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