Japanese Foundation For Cancer Research
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Japanese Foundation For Cancer Research
The (JFCR) is a non-profit cancer research organization based in Ariake, Tokyo. The JFCR was founded in 1908 as the first Japanese organization specializing in cancer by Katsusaburō Yamagiwa and his supporters. The Cancer Institute and its attached hospital of JFCR were set up in 1934. The JFCR became a full member of the Union for International Cancer Control in 1968. Research The Cancer Institute of JFCR is one of the leading medical and biological research institutes in Japan. When the American journal ''Science'' published a special feature on science in Japan in 1992, the institute was described as one of the most productive and most cited institutions in the world at the time. The research at the Institute covers a wide variety of biomedical fields, including biochemistry, cell biology, pathology, carcinogenesis, genomics, system biology, and biomedical engineering. Achievements include the following. *1979: Tadatsugu Taniguchi isolated interferon gene. *1983: Mitsuaki ...
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Familial Adenomatous Polyposis
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous Adenomatous polyps, adenomatous Colorectal polyp, polyps form mainly in the epithelium of the colon (anatomy), large intestine. While these polyps start out benign, malignant transformation into colorectal cancer, colon cancer occurs when they are left untreated. Three variants are known to exist, FAP and attenuated FAP (originally called hereditary flat adenoma syndrome) are caused by APC gene defects on chromosome 5 while autosomal recessive FAP (or MUTYH-associated polyposis) is caused by defects in the ''MUTYH'' gene on chromosome 1. Of the three, FAP itself is the most severe and most common; although for all three, the resulting colonic polyps and cancers are initially confined to the colon wall. Detection and removal before metastasis outside the colon can greatly reduce and in many cases eliminate the spread of cancer. The root cause of FAP is understood to be a genetic mutati ...
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Organizations Established In 1908
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includin ...
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Cancer Organizations Based In Japan
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of a cell. Ty ...
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Foundations Based In Japan
Foundation may refer to: * Foundation (nonprofit), a type of charitable organization ** Foundation (United States law), a type of charitable organization in the U.S. ** Private foundation, a charitable organization that, while serving a good cause, might not qualify as a public charity by government standards * Foundation (cosmetics), a multi-coloured makeup applied to the face * Foundation (evidence), a legal term * Foundation (engineering), the element of a structure which connects it to the ground, and transfers loads from the structure to the ground Arts, entertainment, and media Film and TV * ''The Foundation'', a film about 1960s-1970s Aboriginal history in Sydney, featuring Gary Foley * ''Foundation'' (TV series), an Apple TV+ series adapted from Isaac Asimov's novels * "The Foundation" (''Seinfeld''), an episode * ''The Foundation'' (1984 TV series), a Hong Kong series * ''The Foundation'' (Canadian TV series), a 2009–2010 Canadian sitcom Games * ''Foundation'' ...
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Biomedical Research Foundations
Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)Biomedicine
" NCI Dictionary of Cancer Medicine. .
is a branch of that applies biological and physiological principles to . Biomedicine stresses standardized, evidence-based treatment validated through biological research, with treatment administered via formally trained ...
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1908 Establishments In Japan
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album ''Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipknot. ...
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Cancer Science
''Cancer Science'' is a monthly peer-reviewed medical journal covering research in oncology, which is published by Wiley-Blackwell on behalf of the Japanese Cancer Association. Established in 1907, the journal publishes original articles, editorials, and letters to the editor, describing original research in the fields of basic, translational, and clinical cancer research. The editor-in-chief is Kohei Miyazono (University of Tokyo). According to the Journal Citation Reports, the journal has a 2020 impact factor of 6.71, ranking it 50 out of 242 journals in the category "Oncology". History The journal was established in 1907 as the ''Japanese Journal of Cancer Research'' by Katsusaburō Yamagiwa (University of Tokyo), who first produced tumors in animals by painting tar on their skin. In 1908, he joined the Japanese Foundation for Cancer Research as the first president, and the journal became the official journal of the foundation. The journal was transferred to the Japanese Canc ...
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Japanese Cancer Association
The (JCA) is the oldest professional association related to cancer research in Japan. Based in Shinjuku, Tokyo, it focuses on all aspects of cancer research, including basic, clinical and translational research into the etiology, prevention, diagnosis, and therapy, treatment of cancer. Founded in 1941, the JCA has more than 16,000 members. Purpose and activities The purpose of the JCA is to promote cancer research Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and .... It hosts an annual meeting and other academic meetings (such as symposiums and conferences once or twice a year), holds lectures open to the public, and publishes a journal. The 72nd annual meeting of the Japanese Cancer Association was held at Pacifico Yokohama from October 3 to 5, 2013. History In 1941, Mataro Naga ...
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Kikuko, Princess Takamatsu
, born , was a member of the Japanese Imperial Family. The Princess was married to Prince Takamatsu, the third son of Emperor Taishō and Empress Teimei. She was, therefore, a sister-in-law of Emperor Shōwa and an aunt-in-law of the following emperor, Akihito. She was mainly known for philanthropic activities, particular her patronage of cancer research organizations. At the time of her death, Princess Takamatsu was the oldest member of the Imperial Family. Early life Born in Tokyo on 26 December 1911, she was the second daughter of Yoshihisa Tokugawa (2 September 1884 – 22 January 1922), a peer, and his wife Princess Mieko of Arisugawa (14 February 1891 – 25 April 1933). Her paternal grandfather was Tokugawa Yoshinobu, Japan's last ''shōgun''. Her maternal grandfather, Prince Takehito Arisugawa, was the seventh head of the Arisugawa-no-miya, one of the four ''shinnōke'' or collateral branches of the Imperial Family during the Edo period entitled to provide a successor to ...
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Takashi Sugimura
was a Japanese biochemist, famous for research on chemical carcinogens. He received the Japan Prize for the contribution to establishment of fundamental concept on causes of cancer. He was elected as President of the Japan Academy on October 15, 2013, serving till 2016 and was replaced with Hiroshi Shiono. Contribution Sugimura isolated and identified many mutagens with a structure of heterocyclic amine from foods cooked under ordinary conditions. He showed that tumors induced by these heterocyclic amines had genetic alterations. He further developed his studies to analyze multiple-step carcinogenesis at molecular levels to promote effective primary prevention of cancer. His group identified the novel polymer poly(ADP-ribose) and demonstrated the presence of the enzyme poly ADP ribose polymerase (PARP). He also discovered the cognate catabolic enzyme, poly(ADP-ribose) glycohydrolase (PARG) and further elucidated the biology of poly(ADP-ribose). The discovery of pierisin, an ...
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Tomizo Yoshida
was a prominent Japanese pathologist, famous for discovering the Yoshida sarcoma. In addition, he is known for demonstrating the chemical-induced hepatocarcinogenesis in rats with his mentor Takaoki Sasaki. Yoshida received the Imperial Prize of the Japan Academy twice (1936 and 1953) as well as the Robert Koch Gold Medal (1963). Contribution In the 1930s Yoshida and Sasaki showed the induction of liver cancer in rats by Ortho-Aminoazotoluene. Since that time, a large amount of data has confirmed the carcinogenic activity of Azo dyes. In 1943, Yoshida found a cancer cell line, so-called Yoshida Sarcoma, and experimentally proved that cancer is generated from cancer cells. His findings opened the way of cancer research in terms of cells, and developed biomedical research on chemotherapy. Biography Yoshida was born in Asakawa, Fukushima and graduated from the Medical School, Imperial University of Tokyo in 1927. He was an assistant professor of pathology at the same institutio ...
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