Junctophilin
Junctophilin (JPH, JP) is a protein and associated gene, and may refer to: * JPH1 (JP-1), Junctophilin-1; the gene and the protein it encodes for * JPH2 (JP-2), Junctophilin-2; the gene and the protein it encodes for * JPH3 (JP-3), Junctophilin-3; the gene and the protein it encodes for * JPH4 Junctophilin 4 is a protein in humans that is encoded by the JPH4 gene. This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma ...

JPH3
Junctophilin-3 is a protein that in humans, is encoded by the ''JPH3'' gene. The gene is approximately 97 kilobases long and is located at position 16q24.2. Junctophilin proteins are associated with the formation of junctional membrane complexes linking the plasma membrane with the endoplasmic reticulum in excitable cells. Junctophilin-3 is specific to the brain and has an active role in neurons involved in motor coordination and memory. The protein contains 748 amino acid residues and is composed of a C-terminal hydrophobic segment that spans the endoplasmic/sarcoplasmic reticulum membrane, and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. The protein contains several MORN (membrane occupation and recognition nexus) repeats, that contribute to plasma membrane binding through interactions with phospholipids. Junctophilin-3 is primarily expressed within the brain, specifically the dorsolateral prefrontal cortex. Although the precise fun ...
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JPH2
Junctophilin 2, also known as JPH2, is a protein which in humans is encoded by the ''JPH2'' gene. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. Function Junctional complexes between the plasma membrane and endoplasmic/ sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic membrane occupation and recognition nexus (MORN) domain that shows specific affinity for the plasma membrane. JPH2 is a member of the junctophilin gene family (the other members of the family are JPH1, JPH3, and JPH4 Junctophilin 4 is a protein in humans that is encoded by the JPH4 gene. This gene encodes a member of the junctophilin famil ...
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JPH1
Junctophilin-1 is a protein that in humans is encoded by the ''JPH1'' gene. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. Th ... domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. References Further reading

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