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Julius Adler (biochemist)
Julius Adler Ph.D. (born 1930) is an American biochemist. He has been an Emeritus Professor of biochemistry and genetics at the University of Wisconsin–Madison since 1997. Early life Adler was born in Edelfingen, Germany in 1930. He came to the United States in 1938 at the age of 8 and became a naturalized citizen in 1943. His family settled in Grand Forks, North Dakota where their relatives were among the first Europeans to arrive in 1880. Since he was child, Adler had been fascinated by how organisms sense and respond to the environment. Education Adler attended Harvard University and received his A.B. in Biochemical Sciences in 1952. He then studied with Henry A. Lardy at the University of Wisconsin–Madison and earned an M.S. in Biochemistry in 1954 and a Ph.D. in Biochemistry in 1957. After graduating, Adler did postdoctoral fellowships with Arthur Kornberg in the Department of Microbiology at Washington University School of Medicine (1957–59) and A. Dale Kaiser in t ...
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Bad Mergentheim
Bad Mergentheim (; Mergentheim until 1926; East Franconian German, East Franconian: ''Märchedol'') is a town in the Main-Tauber-Kreis district in the Germany, German state of Baden-Württemberg. It has a population of around 23,000. An officially recognized spa town since 1926, Bad Mergentheim is also known as the headquarters of the Teutonic Order from 1526 until 1809. Geography Subdivisions Since administrative reform in the 1970s the following villages have been part of the municipality: Althausen ''(pop. 600)'', Apfelbach ''(350)'', Dainbach ''(370)'', Edelfingen ''(1,400''; birthplace of the American biochemist Julius Adler (biochemist), Julius Adler), Hachtel ''(360)'', Herbsthausen ''(200)'', Löffelstelzen ''(1,000)'', Markelsheim ''(2,000)'', Neunkirchen ''(1,000)'', Rengershausen ''(480)'', Rot ''(260)'', Stuppach ''(680)'', Wachbach ''(1,300)'' History Mergentheim is mentioned in chronicles as early as 1058, as the residence of the family of the counts of Hohenlohe. Th ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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Methyl-accepting Chemotaxis Protein
The Methyl-accepting chemotaxis proteins (MCP, also aspartate receptor) are a family of transmembrane receptors that mediate chemotactic response in certain enteric bacteria, such as Salmonella typhimurium and Escherichia coli. These methyl-accepting chemotaxis receptors are one of the first components in the sensory excitation and adaptation responses in bacteria, which act to alter swimming behaviour upon detection of specific chemicals. Use of the MCP allows bacteria to detect concentrations of molecules in the extracellular matrix so that the bacteria may smooth swim or tumble accordingly. If the bacterium detects rising levels of attractants ( nutrients) or declining levels of repellents (toxins), the bacterium will continue swimming forward, or smooth swimming. If the bacterium detects declining levels of attractants or rising levels of repellents, the bacterium will tumble and re-orient itself in a new direction. In this manner, a bacterium may swim towards nutrients and ...
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Chemotaxis
Chemotaxis (from '' chemo-'' + ''taxis'') is the movement of an organism or entity in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (e.g., glucose) by swimming toward the highest concentration of food molecules, or to flee from poisons (e.g., phenol). In multicellular organisms, chemotaxis is critical to early development (e.g., movement of sperm towards the egg during fertilization) and development (e.g., migration of neurons or lymphocytes) as well as in normal function and health (e.g., migration of leukocytes during injury or infection). In addition, it has been recognized that mechanisms that allow chemotaxis in animals can be subverted during cancer metastasis. The aberrant chemotaxis of leukocytes and lymphocytes also contribute to inflammatory diseases such as atherosclerosis, asthma, and arthr ...
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Chemoreceptors
A chemoreceptor, also known as chemosensor, is a specialized sensory receptor which transduces a chemical substance (endogenous or induced) to generate a biological signal. This signal may be in the form of an action potential, if the chemoreceptor is a neuron, or in the form of a neurotransmitter that can activate a nerve fiber if the chemoreceptor is a specialized cell, such as taste receptors, or an internal peripheral chemoreceptor, such as the carotid bodies. In physiology, a chemoreceptor detects changes in the normal environment, such as an increase in blood levels of carbon dioxide (hypercapnia) or a decrease in blood levels of oxygen (hypoxia), and transmits that information to the central nervous system which engages body responses to restore homeostasis. In bacteria, chemoreceptors are essential in the mediation of chemotaxis. Cellular chemoreceptors In prokaryotes Bacteria utilize complex long helical proteins as chemoreceptors, permitting signals to travel long di ...
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Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ...
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Wilhelm Pfeffer
Wilhelm Friedrich Philipp Pfeffer (9 March 1845 – 31 January 1920) was a German botanist and plant physiologist born in Grebenstein. Academic career He studied chemistry and pharmacy at the University of Göttingen, where his instructors included Friedrich Wöhler (1800-1882), William Eduard Weber (1804-1891) and Wilhelm Rudolph Fittig (1835-1910). Afterwards, he furthered his education at the universities of Marburg and Berlin. At Berlin, he studied under Alexander Braun (1805-1877) and was an assistant to Nathanael Pringsheim (1823-1894). Later on, he served as an assistant to Julius von Sachs (1832-1897) at Würzburg, In 1873 he was appointed professor of pharmacology and botany at the University of Bonn, followed by professorships at the Universities of Basel (from 1877) and Tübingen (from 1878), where he also served as director of the Botanischer Garten der Universität Tübingen. In 1887 he became a professor at the University of Leipzig and director of its botanical ...
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Monarch Butterfly
The monarch butterfly or simply monarch (''Danaus plexippus'') is a milkweed butterfly (subfamily Danainae) in the family Nymphalidae. Other common names, depending on region, include milkweed, common tiger, wanderer, and black-veined brown. It is amongst the most familiar of North American butterflies and an iconic pollinator, although it is not an especially effective pollinator of milkweeds. Its wings feature an easily recognizable black, orange, and white pattern, with a wingspan of . A Müllerian mimic, the viceroy butterfly, is similar in color and pattern, but is markedly smaller and has an extra black stripe across each hindwing. The eastern North American monarch population is notable for its annual southward late-summer/autumn instinctive migration from the northern and central United States and southern Canada to Florida and Mexico. During the fall migration, monarchs cover thousands of miles, with a corresponding multigenerational return north in spring. The western ...
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Edwin Bret Hart
Edwin Bret Hart (December 25, 1874 – March 12, 1953) was an American biochemist long associated with the University of Wisconsin-Madison. A native of Sandusky, Ohio, Hart studied physiological chemistry in Germany under Albrecht Kossel (recipient of the 1910 Nobel Prize in Physiology or Medicine) at the University of Marburg and University of Heidelberg. Upon his return to the United States, he worked at the New York State Agricultural Experiment Station (part of Cornell University) in Geneva, New York, and then at the University of Michigan before being hired in 1906 by Stephen M. Babcock of the University of Wisconsin to conduct what later came to be known as the "single-grain experiment", which ran from May 1907 to 1911. This experiment entailed a long-term feeding plan using a chemically balanced diet of carbohydrates, fat, and protein instead of single-plant rations as done in Babcock's earlier experiments of 1881 and 1901. Hart directed the experiment, Babcock provi ...
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Esther Lederberg
Esther Miriam Zimmer Lederberg (December 18, 1922 – November 11, 2006) was an American microbiologist and a pioneer of bacterial genetics. She discovered the bacterial virus λ and the bacterial fertility factor F, devised the first implementation of replica plating, and furthered the understanding of the transfer of genes between bacteria by specialized transduction. Lederberg also founded and directed the now-defunct Plasmid Reference Center at Stanford University, where she maintained, named, and distributed plasmids of many types, including those coding for antibiotic resistance, heavy metal resistance, virulence, conjugation, colicins, transposons, and other unknown factors. As a woman in a male-dominated field and the wife of Nobel laureate Joshua Lederberg, Esther Lederberg struggled for professional recognition. Despite her foundational discoveries in the field of microbiology, she was never offered a tenured position at a university. Textbooks often ignore her w ...
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Master Of Science
A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to the Master of Arts degree, the Master of Science degree is typically granted for studies in sciences, engineering and medicine and is usually for programs that are more focused on scientific and mathematical subjects; however, different universities have different conventions and may also offer the degree for fields typically considered within the humanities and social sciences. While it ultimately depends upon the specific program, earning a Master of Science degree typically includes writing a thesis. The Master of Science degree was first introduced at the University of Michigan in 1858. One of the first recipients of the degree was De Volson Wood, who was conferred a Master of Science degree at the University of Michigan in 1859. Al ...
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North Dakota
North Dakota () is a U.S. state in the Upper Midwest, named after the Native Americans in the United States, indigenous Dakota people, Dakota Sioux. North Dakota is bordered by the Canadian provinces of Saskatchewan and Manitoba to the north and by the U.S. states of Minnesota to the east, South Dakota to the south, and Montana to the west. It is believed to host the geographic center of North America, Rugby, North Dakota, Rugby, and is home to the tallest man-made structure in the Western Hemisphere, the KVLY-TV mast. North Dakota is the List of U.S. states and territories by area, 19th largest state, but with a population of less than 780,000 2020 United States census, as of 2020, it is the List of U.S. states and territories by population, 4th least populous and List of U.S. states by population density, 4th most sparsely populated. The capital is Bismarck, North Dakota, Bismarck while the largest city is Fargo, North Dakota, Fargo, which accounts for nearly a fifth of the s ...
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