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Julian Higgins
Julian P. T. Higgins is a British biostatistician, Professor of Evidence Synthesis and Director of Research at the Department of Population Health Sciences at the University of Bristol. Higgins was previously Chair in Evidence Synthesis at the University of York, and Programme Leader at the MRC Biostatistics Unit in Cambridge. He is also a founding trustee and a Past-President of the Society for Research Synthesis Methodology. Early life and education Higgins was born in North Yorkshire, where he attended the Stokesley School. He completed his undergraduate studies in mathematics at Durham University in 1992, earned a diploma in mathematical statistics from the University of Cambridge in 1993, and obtained a PhD in applied statistics from the University of Reading in 1997. Academic career Higgins is a Senior Investigator at the National Institute for Health Research (NIHR). An expert on meta-analysis and systematic review methodologies, Professor Higgins contributes actively to t ...
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Middlesbrough
Middlesbrough ( ) is a town on the southern bank of the River Tees in North Yorkshire, England. It is near the North York Moors national park. It is the namesake and main town of its local borough council area. Until the early 1800s, the area was rural farming land. By 1830, a new industrial town and port started to be developed, driven by the coal and later ironworks. Steel production and ship building began in the late 1800s, remaining associated with the town until post-industrial decline occurred in the late twentieth century. Trade (notably through ports) and digital enterprise sectors contemporarily contribute to the local economy, Teesside University and Middlesbrough College to local education. In 1853, it became a town. The motto ("We shall be" in Latin) was adopted, it reflects ("We have been") of the Bruce clan which were Cleveland's mediaeval lords. The town's coat of arms is three ships representing shipbuilding and maritime trade and an azure (blue) lion, ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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Doug Altman
Douglas Graham Altman FMedSci (12 July 1948 – 3 June 2018) was an English statistician best known for his work on improving the reliability and reporting of medical research and for highly cited papers on statistical methodology. He was professor of statistics in medicine at the University of Oxford, founder and Director of Centre for Statistics in Medicine and Cancer Research UK Medical Statistics Group, and co-founder of the international Equator Network for health research reliability. Professional career Doug Altman graduated in 1970 with an Honours degree in Statistics from Bath University of Technology, now the University of Bath. His first job was in the Department of Community Medicine, St Thomas’s Hospital Medical School, London. He then spent 11 years working for the Medical Research Council's Clinical Research Centre where he worked almost entirely as a statistical consultant in a wide variety of medical areas. In 1988 Doug Altman became head of the newly for ...
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Cochrane (organisation)
Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world. The group conducts systematic reviews of health-care interventions and diagnostic tests and publishes them in the Cochrane Library. According to the Library, articles are available via one-click access, but some require paid subscription or registration before reading. A few reviews, in occupational health for example, incorporate results from non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. History Cochrane, previously known as the Cochrane Collaboration, was founded in 1 ...
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Bias
Bias is a disproportionate weight ''in favor of'' or ''against'' an idea or thing, usually in a way that is closed-minded, prejudicial, or unfair. Biases can be innate or learned. People may develop biases for or against an individual, a group, or a belief. In science and engineering, a bias is a systematic error. Statistical bias results from an unfair sampling of a population, or from an estimation process that does not give accurate results on average. Etymology The word appears to derive from Old Provençal into Old French ''biais'', "sideways, askance, against the grain". Whence comes French ''biais'', "a slant, a slope, an oblique". It seems to have entered English via the game of bowls, where it referred to balls made with a greater weight on one side. Which expanded to the figurative use, "a one-sided tendency of the mind", and, at first especially in law, "undue propensity or prejudice". Types of bias Cognitive biases A cognitive bias is a repeating or basic mi ...
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British Medical Journal
''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Originally called the ''British Medical Journal'', the title was officially shortened to ''BMJ'' in 1988, and then changed to ''The BMJ'' in 2014. The journal is published by BMJ Publishing Group Ltd, a subsidiary of the British Medical Association (BMA). The editor-in-chief of ''The BMJ'' is Kamran Abbasi, who was appointed in January 2022. History The journal began publishing on 3 October 1840 as the ''Provincial Medical and Surgical Journal'' and quickly attracted the attention of physicians around the world through its publication of high-impact original research articles and unique case reports. The ''BMJ''s first editors were P. Hennis Green, lecturer on the diseases of children at the Hunterian School of Medicine, who also was its f ...
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Jonathan Sterne
Jonathan A.C. Sterne is a British statistician, NIHR Senior Investigator, Professor of Medical Statistics and Epidemiology, and the former Head of School of Social and Community Medicine at the University of Bristol. He is co-author of “Essential Medical Statistics”, which received Highly Commended honors in the 2004 BMA Medical Book Competition. Work Sterne has been identified by Clarivate Analytics as the a "Highly Cited Researcher" in each of the last three years, as demonstrated by his production of multiple highly cited papers that rank in the top 1% by citations for field and year in Web of Science. He has a longstanding interest in methodology for systematic reviews and meta-analyses, the clinical epidemiology of HIV and AIDS in the era of antiretroviral therapy, causal inference, methodology for epidemiology and health services research, and epidemiology of asthma and allergic diseases. He has been leading the development of the ROBINS-I tool for assessing risk of bia ...
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ISI Highly Cited
The Institute for Scientific Information (ISI) was an academic publishing service, founded by Eugene Garfield in Philadelphia in 1956. ISI offered scientometric and bibliographic database services. Its specialty was citation indexing and analysis, a field pioneered by Garfield. Services ISI maintained citation databases covering thousands of academic journals, including a continuation of its longtime print-based indexing service the Science Citation Index (SCI), as well as the Social Sciences Citation Index (SSCI) and the Arts and Humanities Citation Index (AHCI). All of these were available via ISI's Web of Knowledge database service. This database allows a researcher to identify which articles have been cited most frequently, and who has cited them. The database provides some measure of the academic impact of the papers indexed in it, and may increase their impact by making them more visible and providing them with a quality label. Some anecdotal evidence suggests that appearing ...
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Systematic Review
A systematic review is a Literature review, scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on the topic, then analyzes, describes, and summarizes interpretations into a refined conclusion. For example, a systematic review of randomized controlled trials is a way of summarizing and implementing evidence-based medicine. While a systematic review may be applied in the Biomedical research, biomedical or health care context, it may also be used where an assessment of a precisely defined subject can advance understanding in a field of research. A systematic review may examine clinical tests, public health interventions, environmental interventions, social interventions, adverse effects, qualitative evidence syntheses, methodological reviews, policy reviews, and economic evaluations. An understanding of systematic review ...
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Meta-analysis
A meta-analysis is a statistical analysis that combines the results of multiple scientific studies. Meta-analyses can be performed when there are multiple scientific studies addressing the same question, with each individual study reporting measurements that are expected to have some degree of error. The aim then is to use approaches from statistics to derive a pooled estimate closest to the unknown common truth based on how this error is perceived. Meta-analytic results are considered the most trustworthy source of evidence by the evidence-based medicine literature.Herrera Ortiz AF., Cadavid Camacho E, Cubillos Rojas J, Cadavid Camacho T, Zoe Guevara S, Tatiana Rincón Cuenca N, Vásquez Perdomo A, Del Castillo Herazo V, & Giraldo Malo R. A Practical Guide to Perform a Systematic Literature Review and Meta-analysis. Principles and Practice of Clinical Research. 2022;7(4):47–57. https://doi.org/10.21801/ppcrj.2021.74.6 Not only can meta-analyses provide an estimate of the un ...
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National Institute For Health Research
The National Institute for Health and Care Research (NIHR) is the British government’s major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "improve the health and wealth of the nation through research". The NIHR was established in 2006 under the government's Best Research for Best Health strategy, and is funded by the Department of Health and Social Care. As a research funder and research partner of the NHS, public health and social care, the NIHR complements the work of the Medical Research Council. NIHR focuses on translational research (translating discoveries from the laboratory to the clinic), clinical research and applied health and social care research. History The NIHR (originally named National Institute for Health Research) was created in April 2006 under the government's health research strategy, Best Research for Best Health. This strategy outlined the direction that ...
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University Of Reading
The University of Reading is a public university in Reading, Berkshire, England. It was founded in 1892 as University College, Reading, a University of Oxford extension college. The institution received the power to grant its own degrees in 1926 by royal charter from King George V and was the only university to receive such a charter between the two world wars. The university is usually categorised as a red brick university, reflecting its original foundation in the 19th century. Reading has four major campuses. In the United Kingdom, the campuses on London Road and Whiteknights are based in the town of Reading itself, and Greenlands is based on the banks of the River Thames in Buckinghamshire. It also has a campus in Iskandar Puteri, Malaysia. The university has been arranged into 16 academic schools since 2016. The annual income of the institution for 2016–17 was £275.3 million of which £35.4 million was from research grants and contracts, with an expenditur ...
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