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Julia Bell
Julia Bell (28 January 1879 – 26 April 1979) was a pioneering English human geneticist.Greta Jones, 'Bell, Julia (1879–1979)', ''Oxford Dictionary of National Biography'', Oxford University Press, Sept 2004; online edn, Jan 200accessed 10 May 2008/ref> Biography She attended Girton College in Cambridge and took the Mathematical Tripos exam in 1901. But because women could not officially receive degrees from Oxford or Cambridge, she was awarded a master's degree at Trinity College, Dublin for her work investigating solar parallax at Cambridge Observatory. In 1908, she moved to University College London and obtained a position there as an assistant in statistics. Her mentor was Karl Pearson (1857–1936), one of the founders of modern statistics, who in 1914 asked her to augment the expertise of the Galton Laboratory staff by taking a degree in medicine. She studied at the London School of Medicine for Women ( Royal Free Hospital). She qualified in 1922 and was elected a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sherwood, Nottingham
Sherwood () is a large district and ward of the city of Nottingham, England, north of the city centre. The population at the 2011 census was 15,414. It is bordered by Woodthorpe to the northeast, Mapperley to the east, Carrington to the south, New Basford and Basford to the west, and Daybrook and Bestwood to the north. It should be carefully distinguished from Sherwood Forest, the Sherwood parliamentary constituency, and Newark and Sherwood district council, all of which lie several miles further north outside the city boundaries. History Several carved, dated stones in buildings indicate development in the area between 1870 and 1910, during the growth of the lace industry. There are also several listed buildings. Sherwood Bus Depot was built in 1900 by Nottingham Corporation Tramways, as part of an initiative to extend the Carrington line to Winchester Street. Trams ran on the route until 6 September 1936 when they were replaced by buses. Part of the premises i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistics
Statistics (from German: '' Statistik'', "description of a state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of surveys and experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey samples. Representative sampling assures that inferences and conclusions can reasonably extend from the sample to the population as a whole. An ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pregnancy
Pregnancy is the time during which one or more offspring develops (gestation, gestates) inside a woman, woman's uterus (womb). A multiple birth, multiple pregnancy involves more than one offspring, such as with twins. Pregnancy usually occurs by sexual intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a Live birth (human), live birth, a miscarriage, an Abortion#Induced, induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the Menstruation#Onset and frequency, last menstrual period (LMP), a span known as the Gestational age (obstetrics), gestational age. This is just over nine months. Counting by Human fertilization#Fertilization age, fertilization age, the length is about 38 weeks. Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; Implantation (embryology), implantation occurs on average 8–9 days after fertilization. An ''embryo'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rubella
Rubella, also known as German measles or three-day measles, is an infection caused by the rubella virus. This disease is often mild, with half of people not realizing that they are infected. A rash may start around two weeks after exposure and last for three days. It usually starts on the face and spreads to the rest of the body. The rash is sometimes itchy and is not as bright as that of measles. Swollen lymph nodes are common and may last a few weeks. A fever, sore throat, and fatigue may also occur. Joint pain is common in adults. Complications may include bleeding problems, testicular swelling, encephalitis, and inflammation of nerves. Infection during early pregnancy may result in a miscarriage or a child born with congenital rubella syndrome (CRS). Symptoms of CRS manifest as problems with the eyes such as cataracts, deafness, as well as affecting the heart and brain. Problems are rare after the 20th week of pregnancy. Rubella is usually spread from one person to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proceedings Of The Royal Society B
''Proceedings of the Royal Society'' is the main research journal of the Royal Society. The journal began in 1831 and was split into two series in 1905: * Series A: for papers in physical sciences and mathematics. * Series B: for papers in life sciences. Many landmark scientific discoveries are published in the Proceedings, making it one of the most historically significant science journals. The journal contains several articles written by the most celebrated names in science, such as Paul Dirac, Werner Heisenberg, Ernest Rutherford, Erwin Schrödinger, William Lawrence Bragg, Lord Kelvin, J.J. Thomson, James Clerk Maxwell, Dorothy Hodgkin and Stephen Hawking. In 2004, the Royal Society began '' The Journal of the Royal Society Interface'' for papers at the interface of physical sciences and life sciences. History The journal began in 1831 as a compilation of abstracts of papers in the ''Philosophical Transactions of the Royal Society'', the older Royal Society publicatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X Chromosome
The X chromosome is one of the two sex-determining chromosomes (allosomes) in many organisms, including mammals (the other is the Y chromosome), and is found in both males and females. It is a part of the XY sex-determination system and XO sex-determination system. The X chromosome was named for its unique properties by early researchers, which resulted in the naming of its counterpart Y chromosome, for the next letter in the alphabet, following its subsequent discovery. Discovery It was first noted that the X chromosome was special in 1890 by Hermann Henking in Leipzig. Henking was studying the testicles of ''Pyrrhocoris'' and noticed that one chromosome did not take part in meiosis. Chromosomes are so named because of their ability to take up staining (''chroma'' in Greek means ''color''). Although the X chromosome could be stained just as well as the others, Henking was unsure whether it was a different class of object and consequently named it ''X element'', which later ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemophilia
Haemophilia, or hemophilia (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. Those with a mild case of the disease may have symptoms only after an accident or during surgery. Bleeding into a joint can result in permanent damage while bleeding in the brain can result in long term headaches, seizures, or a decreased level of consciousness. There are two main types of haemophilia: haemophilia A, which occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from one's parents through an X chromosome carrying a nonfunctional gene. Rarely a new mutation may occur during early development or haemophilia may develop later in life due to antibodies forming agains ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colourblindness
Color blindness or color vision deficiency (CVD) is the decreased ability to see color or differences in color. It can impair tasks such as selecting ripe fruit, choosing clothing, and reading traffic lights. Color blindness may make some academic activities more difficult. However, issues are generally minor, and the colorblind automatically develop adaptations and coping mechanisms. People with total color blindness (achromatopsia) may also be uncomfortable in bright environments and have decreased visual acuity. The most common cause of color blindness is an inherited problem or variation in the functionality of one or more of the three classes of cone cells in the retina, which mediate color vision. The most common form is caused by a genetic disorder called congenital red–green color blindness. Males are more likely to be color blind than females, because the genes responsible for the most common forms of color blindness are on the X chromosome. Non-color-blind fem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Linkage
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more ''linked'' than markers that are far apart. In other words, the nearer two genes are on a chromosome, the lower the chance of recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly ''unlinked'', although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located. Genetic linkage is the most prominent exception to Gregor Mendel's Law of Independent Assortment. The first experiment to demonstra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galton Laboratory
The Galton Laboratory was a laboratory for research into eugenics and then into human genetics based at University College London in London, England. It was originally established in 1904, and became part of UCL's biology department in 1996. The ancestor of the Galton Laboratory was the Eugenics Record Office founded by Francis Galton in 1904. In 1907 the Office was reconstituted as the Galton Eugenics Laboratory as part of UCL and under the direction of Karl Pearson the Professor of Applied Mathematics. Galton financed the Laboratory and on his death left UCL enough money to create a chair in National Eugenics which Pearson filled. The Laboratory published a series of memoirs and in 1925 Pearson created the ''Annals of Eugenics'', which continues as the ''Annals of Human Genetics''. The journal has always been edited at the Galton. Pearson was succeeded as Galton Professor by R. A. Fisher in 1934. When Fisher moved to Cambridge in 1944 the laboratory was incorporated in an enlar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
