Joseph Paruta
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Joseph Paruta
Joseph Paruta, also known as "Old Man" (December 3, 1929 – October 1986), was a respected soldier in the Gambino crime family and considered a "key member" of Sammy Gravano's Bensonhurst, Brooklyn crew. He is the only known mobster who asked for a mercy killing after becoming terminally ill with lung cancer. The proposition was not agreed upon by John Gotti but Paruta died before the mercy killing was performed. Biography Paruta was born in Bensonhurst on December 3, 1929 to first-generation emigrants from Venice, Italy of a Luccan family from Tuscany. He was the oldest of three children, who grew up in poverty. Paruta was originally an associate who served in the crew of Gambino crime family capo Salvatore Aurello. He served in the Gambino crime family under the tutelage of Carlo Gambino and later Paul Castellano. Sammy Gravano later said, "Everybody called Joe the 'Old Man'. He was only about fifteen years older than me (Gravano was born on March 12, 1945) but he already ha ...
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American Mafia
The American Mafia, commonly referred to in North America as the Italian American Mafia, the Mafia, or the Mob, is a highly organized Italian American criminal society and organized crime group. The organization is often referred to by its members as Cosa Nostra (, "our thing" or "this thing of ours") and by the American government as La Cosa Nostra (LCN). The organization's name is derived from the original ''Mafia'' or ''Cosa nostra'', the Sicilian Mafia, with "American Mafia" originally referring simply to Mafia (or ''Cosa nostra'') groups from Sicily operating in the United States, as the organization initially emerged as an offshoot of the Sicilian Mafia (known also as ''Cosa nostra'' by its members) formed by Italian immigrants in the United States. However, the organization gradually evolved into a separate entity partially independent of the original Mafia in Sicily, and it eventually encompassed or absorbed other Italian immigrant and Italian-American gangsters and Italia ...
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Edward Garofalo
Edward is an English given name. It is derived from the Anglo-Saxon name ''Ēadweard'', composed of the elements '' ēad'' "wealth, fortune; prosperous" and '' weard'' "guardian, protector”. History The name Edward was very popular in Anglo-Saxon England, but the rule of the Norman and Plantagenet dynasties had effectively ended its use amongst the upper classes. The popularity of the name was revived when Henry III named his firstborn son, the future Edward I, as part of his efforts to promote a cult around Edward the Confessor, for whom Henry had a deep admiration. Variant forms The name has been adopted in the Iberian peninsula since the 15th century, due to Edward, King of Portugal, whose mother was English. The Spanish/Portuguese forms of the name are Eduardo and Duarte. Other variant forms include French Édouard, Italian Edoardo and Odoardo, German, Dutch, Czech and Romanian Eduard and Scandinavian Edvard. Short forms include Ed, Eddy, Eddie, Ted, Teddy and Ned. Peop ...
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Consigliere
Consigliere ( , ; plural ) is a position within the leadership structure of the Sicilian, Calabrian, and Italian-American Mafia. The word was popularized in English by the novel ''The Godfather'' (1969) and its film adaptation. In the novel, a consigliere is an advisor or counselor to the boss, with the additional responsibility of representing the boss in important meetings both within the boss's crime family and with other crime families. The consigliere is a close, trusted friend and confidant, the mob's version of an elder statesman. They are an advisor to the boss in a Mafia crime family, and sometimes is their "right-hand man". By the very nature of the job, a consigliere is one of the few in the family who can argue with the boss, and is often tasked with challenging the boss when needed, to ensure subsequent plans are foolproof.
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Robert DiBernardo
Robert "DiB" DiBernardo (May 31, 1937 in Hewlett, New York – June 5, 1986) was a member of the Gambino crime family and one of John Gotti's subordinates, who was reputed to control much of the commercial pornography in the US. During the 1984 US presidential election, publicity about DiBernardo having rented business premises from the husband of Geraldine Ferraro embroiled her in damaging media innuendo about organized crime. By some accounts, DiBernardo was ''the'' major figure behind the US adult industry. In any event, he was a relatively capable businessman who did not have any personal reputation for involvement in violence, but his Mafia links deterred potential competitors and warded off other criminals. He became immensely influential in the US pornography business, and an associate of Reuben Sturman. Whether DiBernardo's relationship with Sturman and others was based on outright extortion or mutual advantage was never established. DiBernardo was seen as a phenomenal ...
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Made Man
In the American and Sicilian Mafia, a made man is a fully initiated member of the Mafia. To become "made", an associate first must be Italian or of Italian descent and sponsored by another made man. An inductee will be required to take the oath of ''omertà'', the Mafia code of silence and code of honor. After the induction ceremony, the associate becomes a "made man" and holds the rank of soldier (Italian: ''soldato'') in the Mafia hierarchy. Made men are the only ones who can rise through the ranks of the Mafia, from soldier to caporegime, consigliere, underboss, and boss. Other common names for members include ''man of honor'' ( it, uomo d'onore), ''man of respect'' (Italian: ''uomo di rispetto''), ''one of us'', ''friend of ours'' (Italian: ''amico nostro''), ''good fella'', and ''wiseguy''; although the last two terms can also apply to non-initiated Mafia associates who work closely with the Mafia, rather than just official "made men". Earning or making one's "bones" or " ...
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Lung Cancer
Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from transformed, malignant cells that originate as epithelial cells, or from tissues composed of epithelial cells. Other lung cancers, such as the rare sarcomas of the lung, are generated by the malignant transformation of connective tissues (i.e. nerve, fat, muscle, bone), which arise from mesenchymal cells. Lymphomas and melanomas (from lymphoid and melanocyte cell lineages) can also rarely result in lung cancer. In time, this uncontrolled neoplasm, growth can metastasis, metastasize (spreading beyond the lung) either by direct extension, by entering the lymphatic circulation, or via hematogenous, bloodborne spread – into nearby tissue or other, more distant parts of the body. Most cancers that originate from within the lungs, known as primary ...
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Manhattan, New York
Manhattan (), known regionally as the City, is the most densely populated and geographically smallest of the five boroughs of New York City. The borough is also coextensive with New York County, one of the original counties of the U.S. state of New York. Located near the southern tip of New York State, Manhattan is based in the Eastern Time Zone and constitutes both the geographical and demographic center of the Northeast megalopolis and the urban core of the New York metropolitan area, the largest metropolitan area in the world by urban landmass. Over 58 million people live within 250 miles of Manhattan, which serves as New York City’s economic and administrative center, cultural identifier, and the city’s historical birthplace. Manhattan has been described as the cultural, financial, media, and entertainment capital of the world, is considered a safe haven for global real estate investors, and hosts the United Nations headquarters. New York City is the headquarters of ...
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Memorial Sloan-Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute–designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue, between 67th and 68th streets, in Manhattan. According to U.S. News & World Report 2021-2022 Best Hospitals, Memorial Sloan Kettering Cancer Center (MSK) has been ranked as the number two hospital for cancer care in the nation. History New York Cancer Hospital (1884–1934) Memorial Hospital was founded on the Upper West Side of Manhattan in 1884 as the New York Cancer Hospital by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in th ...
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Heart Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximatel ...
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Recessive
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and the second recessive. This state of having two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes ( autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one copy of the Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, there are other forms of dominance such as incomplete d ...
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Autosomal
An autosome is any chromosome that is not a sex chromosome. The members of an autosome pair in a diploid cell have the same morphology, unlike those in allosome, allosomal (sex chromosome) pairs, which may have different structures. The DNA in autosomes is collectively known as atDNA or auDNA. For example, humans have a diploid human genome, genome that usually contains 22 pairs of autosomes and one allosome pair (46 chromosomes total). The autosome pairs are labeled with numbers (1–22 in humans) roughly in order of their sizes in base pairs, while allosomes are labelled with their letters. By contrast, the allosome pair consists of two X chromosomes in females or one X and one Y chromosome in males. Unusual combinations of XYY syndrome, XYY, Klinefelter syndrome, XXY, Triple X syndrome, XXX, XXXX syndrome, XXXX, XXXXX syndrome, XXXXX or XXYY syndrome, XXYY, among Aneuploidy, other Salome combinations, are known to occur and usually cause developmental abnormalities. Autosomes ...
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Werner Syndrome
Werner syndrome (WS) or Werner's syndrome, also known as "adult progeria",James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . is a rare, autosomal recessive disorder which is characterized by the appearance of premature aging. Werner syndrome is named after the German scientist Otto Werner. He identified the syndrome in four siblings observed with premature aging, which he explored as the subject of his dissertation of 1904. It has a global incidence rate of less than 1 in 100,000 live births (although incidence in Japan and Sardinia is higher, affecting 1 in 20,000–40,000 and 1 in 50,000, respectively). 1,300 cases had been reported as of 2006. Affected individuals typically grow and develop normally until puberty; the mean age of diagnosis is twenty-four, often realized when the adolescent growth spurt is not observed. The youngest person diagnosed was six years old. The median and mean ages of ...
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