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Joseph F. Holson
Joseph F. Holson, an American scientist, business executive, and educator in the disciplines of toxicology and product development, served as President of WIL Research Laboratories for 20 years (1988-2008). He is known for his contributions to the fields of developmental and reproductive toxicology (DART), pharmacokinetics, and risk assessment, including extensive experience with study design, data interpretation, and interspecies extrapolation of health effects data. He has served in numerous U.S. EPA/FDA advisory committees and as an expert toxicology witness. He was elected to two National Academy of Sciences toxicology committees. Dr. Holson is an editor and author of the textbook ''Regulatory Toxicology'' and an author of two significant chapters in the textbook ''Developmental and Reproductive Toxicology: A Practical Approach, Second Edition''. Two of his peer-reviewed articles were recognized by the Risk Assessment Specialty Section of the Society of Toxicology as the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicologist
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pediatrics
Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the age of 18. The American Academy of Pediatrics recommends people seek pediatric care through the age of 21, but some pediatric subspecialists continue to care for adults up to 25. Worldwide age limits of pediatrics have been trending upward year after year. A medical doctor who specializes in this area is known as a pediatrician, or paediatrician. The word ''pediatrics'' and its cognates mean "healer of children," derived from the two Greek words: (''pais'' "child") and (''iatros'' "doctor, healer"). Pediatricians work in clinics, research centers, universities, general hospitals and children's hospitals, including those who practice pediatric subspecialties (e.g. neonatology requires resources available in a NICU). History The ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fiduciary
A fiduciary is a person who holds a legal or ethical relationship of trust with one or more other parties (person or group of persons). Typically, a fiduciary prudently takes care of money or other assets for another person. One party, for example, a corporate trust company or the trust department of a bank, acts in a fiduciary capacity to another party, who, for example, has entrusted funds to the fiduciary for safekeeping or investment. Likewise, financial advisers, financial planners, and asset managers, including managers of pension plans, endowments, and other tax-exempt assets, are considered fiduciaries under applicable statutes and laws. In a fiduciary relationship, one person, in a position of vulnerability, justifiably vests confidence, good faith, reliance, and trust in another whose aid, advice, or protection is sought in some matter... In such a relation, good conscience requires the fiduciary to act at all times for the sole benefit and interest of the one who trust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Diego State University
San Diego State University (SDSU) is a public research university in San Diego, California. Founded in 1897 as San Diego Normal School, it is the third-oldest university and southernmost in the 23-member California State University (CSU) system. In Fall 2022, SDSU hit an all time high enrollment record student body of nearly 37,000 and an alumni base of more than 300,000. It is classified among "R2: Doctoral Universities – High research activity". In the 2015–16 fiscal year, the university obtained $130 million in public and private funding—a total of 707 awards—up from $120.6 million the previous fiscal year. As reported by the Faculty Scholarly Productivity Index released by the Academic Analytics organization of Stony Brook, New York, SDSU had the highest research output of any small research university in the United States in 2006 and 2007. SDSU sponsors the second-highest number of Fulbright Scholars in the State of California, just behind UC Berkeley. Since 2005, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Arizona
The University of Arizona (Arizona, U of A, UArizona, or UA) is a public land-grant research university in Tucson, Arizona. Founded in 1885 by the 13th Arizona Territorial Legislature, it was the first university in the Arizona Territory. The university is part of the Association of American Universities and the Universities Research Association. In the former, it is the only member from the state of Arizona. The university is classified among "R1: Doctoral Universities – Very High Research Activity". The University of Arizona is one of three universities governed by the Arizona Board of Regents. , the university enrolled 49,471 students in 19 separate colleges/schools, including the University of Arizona College of Medicine in Tucson and Phoenix and the James E. Rogers College of Law, and is affiliated with two academic medical centers ( Banner – University Medical Center Tucson and Banner – University Medical Center Phoenix). In 2021, University of Arizona acquired ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Applications International Corporation
Science Applications International Corporation (SAIC), Inc. is an American technology company headquartered in Reston, Virginia that provides government services and information technology support. History The original SAIC was created in 1969 by J. Robert Beyster. Then on September 27, 2013, it spun off a $4 billion unit which retained its name, while the parent company changed its name to Leidos. Following the split, Anthony J. Moraco was appointed CEO of SAIC, and John P. Jumper was appointed CEO of Leidos. The primary motivation for the spinoff was the conflicts of interest provisions in the Federal Acquisition Regulation which prevented the company from bidding on some new contracts because of existing contracts. On May 4, 2015, SAIC acquired Scitor Holdings, Inc. for $790 million to expand their presence in the intelligence industry through classified contracts, cleared personnel, and a robust security infrastructure. Scitor was previously owned by Leonard G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Little Rock, Arkansas
(The Little Rock, The "Little Rock") , government_type = council-manager government, Council-manager , leader_title = List of mayors of Little Rock, Arkansas, Mayor , leader_name = Frank Scott Jr. , leader_party = Democratic Party (United States), D , leader_title2 = City council, Council , leader_name2 = Little Rock Board of Directors , unit_pref = Imperial , area_total_sq_mi = 123.00 , area_total_km2 = 318.58 , area_land_sq_mi = 120.05 , area_land_km2 = 310.92 , area_metro_sq_mi = 4090.34 , area_metro_km2 = 10593.94 , population_as_of = 2020 United States Census, 2020 , population_est = , pop_est_as_of = , population_demonym = Little Rocker , population_footnotes = , population_total = 202591 , population_rank = US: List of United States cities by population, 118 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Good Laboratory Practice
In the experimental (non-clinical) research arena, good laboratory practice or GLP is a quality system of management controls for research laboratories and organizations to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of products in development for human or animal health (including pharmaceuticals) through non-clinical safety tests; from physio-chemical properties through acute to chronic toxicity tests. GLP was first introduced in New Zealand and Denmark in 1972, and later in the US in 1978 in response to the Industrial BioTest Labs scandal. It was followed a few years later by the Organization for Economic Co-operation and Development (OECD) Principles of GLP in 1992; the OECD has since helped promulgate GLP to many countries. GLP applies to non-clinical studies conducted for the assessment of the safety or efficacy of products in development (including pharmaceuticals) for people, animals, and the environment. GLP, a data and opera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birth Defect
A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of a body part and functional disorders in which problems exist with how a body part works. Functional disorders include metabolic and degenerative disorders. Some birth defects include both structural and functional disorders. Birth defects may result from genetic or chromosomal disorders, exposure to certain medications or chemicals, or certain infections during pregnancy. Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. Many are believed to involve multiple factors. Birth defects may be visi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Toxicology Program
The National Toxicology Program (NTP) is an inter-agency program run by the United States Department of Health and Human Services to coordinate, evaluate, and report on toxicology within public agencies. The National Toxicology Program is headquartered at the National Institute of Environmental Health Sciences (NIEHS). The NIEHS Director, currently Dr. Richard Woychik, Ph.D., also concurrently serves as NTP Director. History The program was established in 1978 by Joseph A. Califano Jr., then the United States Secretary of Health, Education, and Welfare (today known as the Secretary of Health and Human Services). The program arose from congressional concerns about the health effects of chemical agents in the environment. In October 1981, Secretary Richard S. Schwiker granted permanent status to the program. Interagency Center for Evaluation of Alternative Toxicological Methods The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) supports th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teratology
Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology. The related term developmental toxicity includes all manifestations of abnormal development that are caused by environmental insult. These may include growth retardation, delayed mental development or other congenital disorders without any structural malformations. Teratogens are substances that may cause birth defects via a toxic effect on an embryo or fetus. Known teratogens include: retinol, thalidomide, mercury, alcohol, lead, polychlorinated biphenyls (PCBs), and 2,3,7,8-tetrachlorodibenzodioxin. Etymology The term was borrowed in 1842 from the French , where it was formed in 1830 from the Greek (word stem ), meaning "sign sent by the gods, portent, marvel, monster", and ('' -ology''), used to designate a discourse, treaty, science, theory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louisiana State University
Louisiana State University (officially Louisiana State University and Agricultural and Mechanical College, commonly referred to as LSU) is a public land-grant research university in Baton Rouge, Louisiana. The university was founded in 1860 near Pineville, Louisiana, under the name Louisiana State Seminary of Learning & Military Academy. The current LSU main campus was dedicated in 1926, consists of more than 250 buildings constructed in the style of Italian Renaissance architect Andrea Palladio, and the main campus historic district occupies a plateau on the banks of the Mississippi River. LSU is the flagship school of the state of Louisiana, as well as the flagship institution of the Louisiana State University System, and is the most comprehensive university in Louisiana. In 2021, the university enrolled over 28,000 undergraduate and more than 4,500 graduate students in 14 schools and colleges. Several of LSU's graduate schools, such as the E. J. Ourso College of Business ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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