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John Wikswo
John Peter Wikswo, Jr. (born October 6, 1949) is a biological physicist at Vanderbilt University. He was born in Lynchburg, Virginia, United States. Wikswo is noted for his work on biomagnetism and cardiac electrophysiology. Graduate school In the 1970s, Wikswo was a graduate student at Stanford University, where he worked under physicist William M. Fairbank, studying magnetocardiography. Biomagnetism In 1977 he became an assistant professor in the Department of Physics and Astronomy at Vanderbilt University, where he set up a laboratory to study living state physics. In 1980, he made the first measurement of the magnetic field of an isolated nerve, by threading the a frog sciatic nerve through a wire-wound, ferrite-core toroid and detecting the induced current using a SQUID magnetometer. At the same time, Wikswo and Ken Swinney calculated the magnetic field of a nerve axon. This work was followed a few years later by the first detailed comparison of the measured a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lynchburg, Virginia
Lynchburg is an independent city (United States), independent city in the Commonwealth (U.S. state), Commonwealth of Virginia in the United States. First settled in 1757 by ferry owner John Lynch (1740–1820), John Lynch, the city's population was 79,009 at the 2020 United States census, 2020 census. Located in the foothills of the Blue Ridge Mountains along the banks of the James River, Lynchburg is known as the "City of Seven Hills" or the "Hill City". In the 1860s, Lynchburg was the only city in Virginia that was not recaptured by the Union (American Civil War), Union before the end of the American Civil War. Lynchburg lies at the center of a wider Lynchburg metropolitan area, metropolitan area close to the geographic center of Virginia. It is the fifth-largest Metropolitan statistical area, MSA in Virginia, with a population of 261,593. It is the site of several institutions of higher education, including Virginia University of Lynchburg, Randolph College, University of L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voltage Sensitive Dyes
Voltage-sensitive dyes, also known as potentiometric dyes, are dyes which change their spectral properties in response to voltage changes. They are able to provide linear measurements of firing activity of single neurons, large neuronal populations or activity of myocytes. Many physiological processes are accompanied by changes in cell membrane potential which can be detected with voltage sensitive dyes. Measurements may indicate the site of action potential origin, and measurements of action potential velocity and direction may be obtained. Potentiometric dyes are used to monitor the electrical activity inside cell organelles where it is not possible to insert an electrode, such as the mitochondria and dendritic spine. This technology is especially powerful for the study of patterns of activity in complex multicellular preparations. It also makes possible the measurement of spatial and temporal variations in membrane potential along the surface of single cells. Types of dyes Fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomedical Engineering Society
BMES (the Biomedical Engineering Society) is the professional society for students, faculty, researcher and industry working in the broad area of biomedical engineering. BMES is the leading biomedical engineering society in the United States and was founded on February 1, 1968 "to promote the increase of biomedical engineering Biomedical engineering (BME) or medical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes (e.g., diagnostic or therapeutic). BME is also traditionally logical sciences ... knowledge and its utilization." There are 7,000 members in 2018. Since 1972, the society has published an academic journal, the ''Annals of Biomedical Engineering''online archive. History The BMES was first established in Illinois on February 1, 1968 as a non-profit organization that aims to serve the biomedical engineering students, academics, researchers, and professionals. Upon establishing the organizati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Heart Association
The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. Originally formed in New York City in 1924, it is currently headquartered in Dallas, Texas. The American Heart Association is a national voluntary health agency. They are known for publishinguidelineson cardiovascular disease and prevention, standards on basic life support, advanced cardiac life support (ACLS), and pediatric advanced life support (PALS), and in 2014 issued its first guidelines for preventing strokes in women. They are known also for operating a number of highly visible public service campaigns starting in the 1970s, and also operate a number of fundraising events. In 1994, the ''Chronicle of Philanthropy'', an industry publication, released a study that showed the American H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Institute For Medical And Biological Engineering
The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington. It represents 50,000 medical and biomedical engineers, and academic institutions, private industry, and professional engineering societies. College of Fellows Since AIMBE’s inception, over 2,000 individuals have been inducted to AIMBE’s College of Fellows. These fellows include heads of medical and engineering schools. Some Fellows work for the government, acting as consultants, or directing clinical trials. Some Fellows are members of other prominent academic institutions, such as the National Academy of Engineering, Institute of Medicine and the National Academy of Sciences. Others have received the National Medal of Science and the National Medal of Technology. Fellows use the post-nominal FAIMBE. Industry Council The Industry Council consists of corporate leaders in the biomedical engineering field. Partnership with FDA AIM ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Physical Society
The American Physical Society (APS) is a not-for-profit membership organization of professionals in physics and related disciplines, comprising nearly fifty divisions, sections, and other units. Its mission is the advancement and diffusion of knowledge of physics. The society publishes more than a dozen scientific journals, including the prestigious '' Physical Review'' and ''Physical Review Letters'', and organizes more than twenty science meetings each year. APS is a member society of the American Institute of Physics. Since January 2021 the organization has been led by chief executive officer Jonathan Bagger. History The American Physical Society was founded on May 20, 1899, when thirty-six physicists gathered at Columbia University for that purpose. They proclaimed the mission of the new Society to be "to advance and diffuse the knowledge of physics", and in one way or another the APS has been at that task ever since. In the early years, virtually the sole activity of the AP ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University School Of Medicine
Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. This medical institution, then called Cooper Medical College, was acquired by Stanford in 1908. The medical school moved to the Stanford campus near Palo Alto, California, in 1959. The School of Medicine, along with Stanford Health Care and Lucile Packard Children's Hospital, is part of Stanford Medicine. Stanford Health Care was ranked the fourth best hospital in California (behind UCLA Medical Center, Cedars-Sinai Medical Center, and UCSF Medical Center, respectively). History In 1855, Illinois physician Elias Samuel Cooper moved to San Francisco in the wake of the California Gold Rush. In cooperation with the University of the Pacific (also known as California Wesleyan College), Cooper established the Medical Department of the Univers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Virginia
The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United States, with College admissions in the United States, highly selective admission. Set within the The Lawn, Academical Village, a World Heritage Site, UNESCO World Heritage Site, the university is referred to as a "Public Ivy" for offering an academic experience similar to that of an Ivy League university. It is known in part for certain rare characteristics among public universities such as #1800s, its historic foundations, #Honor system, student-run academic honor code, honor code, and Secret societies at the University of Virginia, secret societies. The original governing Board of Visitors included three List of presidents of the United States, U.S. presidents: Thomas Jefferson, Jefferson, James Madison, and James Monroe. The latter as si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microwell Plate
A microplate, also known as a microtiter plate (''Microtiter'' is a registered trademark in the United States, therefore it should not be used generically without attribution), microwell plate or multiwell, is a flat plate with multiple "wells" used as small test tubes. The microplate has become a standard tool in analytical research and clinical diagnostic testing laboratories. A very common usage is in the enzyme-linked immunosorbent assay (ELISA), the basis of most modern medical diagnostic testing in humans and animals. A microplate typically has 6, 12, 24, 48, 96, 384 or 1536 sample wells arranged in a 2:3 rectangular matrix. Some microplates have been manufactured with 3456 or 9600 wells, and an "array tape" product has been developed that provides a continuous strip of microplates embossed on a flexible plastic tape. Each well of a microplate typically holds somewhere between tens of nanolitres to several millilitres of liquid. They can also be used to store dry powder ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicology
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neocla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ-on-a-chip
An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have bee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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