John T. Dingle
   HOME
*





John T. Dingle
John T. Dingle is a British biologist and rheumatologist. He joined the staff of the Strangeways Research Laboratory in 1959 as a research assistant to then-director Honor Fell, and later himself served as director from 1979 to 1993, taking over the position after the death of Michael Abercrombie. His presence at Strangeways helped to move its research direction toward the original research interests of its founder, Thomas Strangeways, who sought to understand the physiology of arthritis and other rheumatic diseases, after many years in which the laboratory specialized more narrowly in tissue culture and cell biology. Dingle was the president of Hughes Hall from 1993 to 1998, and is an honorary fellow. He was the founding chairman of the British Connective Tissue Society (now the British Society for Matrix Biology), serving from 1980 to 1987. From 1975 to 1982 he was Chairman of the Editorial Board of the ''Biochemical Journal''. Among his notable trainees is University of Califor ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Strangeways Research Laboratory
Strangeways Research Laboratory is a research institution in Cambridge, United Kingdom. It was founded by Thomas Strangeways in 1905 as the Cambridge Research Hospital and acquired its current name in 1928. Organised as an independent charity, it was historically funded primarily by the Medical Research Council and is currently managed by the University of Cambridge, also its sole trustee. Formerly a site of research on rheumatic arthritis and connective tissue disorders, it has since 1997 focused on the study of genetic epidemiology. History The institution was founded in 1905 as the Cambridge Research Hospital by physician Thomas Strangeways, who sought to study patients suffering from rheumatoid arthritis and related conditions. Funded by a combination of Strangeways' own contributions, support from noted doctors of the time, and donations from patients, the hospital began modestly with only six beds, and with research equipment located in renovated coal sheds. It closed b ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Hughes Hall
Hughes Hall is a constituent college of the University of Cambridge in England. It is the oldest of the University of Cambridge's postgraduate colleges. The college also admits undergraduates, though undergraduates admitted by the college must be aged 21 or over. There is no age requirement for postgraduate students. The majority of Hughes Hall students are postgraduate, although nearly one-fifth of the student population comprises individuals aged 21 and above who are studying undergraduate degree courses at the university. Hughes Hall was founded in the 19th century as the Cambridge Training College for Women with the purpose of providing a college of the university dedicated to training women graduates for the teaching profession. Since then it has enlarged and expanded to support a community of students and researchers, both male and female, working in all the academic domains encompassed by the University of Cambridge. The college is housed in a number of 19th and 20th cent ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Rheumatologist
Rheumatology (Greek ''ῥεῦμα'', ''rheûma'', flowing current) is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. Rheumatology covers more than 100 different complex diseases, collectively known as rheumatic diseases, which includes many forms of arthritis as well as lupus and Sjögren's syndrome. Doctors who have undergone formal training in rheumatology are called rheumatologists. Many of these diseases are now known to be disorders of the immune system, and rheumatology has significant overlap with immunology, the branch of medicine that studies the immune system. Rheumatologist A rheumatologist is a physician who specializes in the field of medical sub-specialty called rheumatology. A rheumatologist holds a board certification after specialized training. In the United States, training in this field requires four years undergraduate school, four years ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Honor Fell
Dame Honor Bridget Fell, DBE, FRS (22 May 1900 – 22 April 1986) was a British scientist and zoologist. Her contributions to science included the development of experimental methods in organ culture, tissue culture, and cell biology. Early life and education Fell was born to Colonel William Edwin Fell and Alice Fell at Fowthorpe near Filey in Yorkshire on 22 May 1900, the youngest of nine children. She had six sisters and two brothers, the younger of the two brothers, with down syndrome, died at the age of eight. Fell was known as the baby of the family. Her father was a minor landowner but cannot be said to have been a successful farmer. On the other hand her mother was a very practical and capable carpenter. Both school and family records highlight her childhood love of pet ferrets. Fell carried her pet ferret, Janie, to her sister Barbara's wedding when she was only thirteen. Fell had little contact with her family until the 1960s when one of her nephews, Henry Fell, and h ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Michael Abercrombie
Michael Abercrombie FRS (14 August 1912 – 28 May 1979) was a British cell biologist and embryologist. He was one of four children of the poet Lascelles Abercrombie. Early life Michael was born at Ryton near Dymock in Gloucestershire on 14 August 1912, the third son of Lascelles Abercrombie, poet and critic, and his wife, Catherine, daughter of Owen Gwatkin, a surgeon at Grange-over-Sands.Dictionary of National Biography 1971-1980 His uncle was the famed British town planner, Patrick Abercrombie. Abercrombie went to school at Liverpool College and then Leeds Grammar School. In 1931 he entered Queen's College, University of Oxford, to study Zoology under Professor Gavin de Beer, supported by a Hastings scholarship. He was awarded a first class B. Sc. degree in 1934. Later life He moved to the Strangeways Research Laboratory at the University of Cambridge to undertake doctoral research. In 1938 was employed at University of Birmingham as a lecturer, while also holding a resea ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Thomas Strangeways
Thomas Strangeways Pigg Strangeways (1866–1926) was a British pathologist, known for founding the Cambridge Research Hospital, which was renamed the Strangeways Research Laboratory following Strangeways' death in 1926. Education and early career Strangeways was born Thomas Strangeways Pigg in 1866. Strangeways studied under Alfredo Kanthack at St Bartholomew's Hospital and received his medical degree in 1890. He followed Kanthack to the University of Cambridge after Kanthack was offered the chair of the Pathology Department there. Strangeways became a demonstrator and subsequently a lecturer in pathology at the University of Cambridge. Founding of Cambridge Research Hospital Strangeways developed an interest in the pathology of rheumatoid arthritis and in 1905 founded the Cambridge Research Hospital in order to study patients with this condition and related ones. Funded largely by Strangeways himself, noted doctors of his acquaintance, and donations from patients, the hospital ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Arthritis
Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. Onset can be gradual or sudden. There are over 100 types of arthritis. The most common forms are osteoarthritis (degenerative joint disease) and rheumatoid arthritis. Osteoarthritis usually occurs with age and affects the fingers, knees, and hips. Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. Other types include gout, lupus, fibromyalgia, and septic arthritis. They are all types of rheumatic disease. Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be useful. Recommended medications may depend on the form of arthritis. These may include pain medications such as ibuprofen ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Tissue Culture
Tissue culture is the growth of tissues or cells in an artificial medium separate from the parent organism. This technique is also called micropropagation. This is typically facilitated via use of a liquid, semi-solid, or solid growth medium, such as broth or agar. Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. Historical use In 1885 Wilhelm Roux removed a section of the medullary plate of an embryonic chicken and maintained it in a warm saline solution for several days, establishing the basic principle of tissue culture. In 1907 the zoologist Ross Granville Harrison demonstrated the growth of frog embryonic cells that would give rise to nerve cells in a medium of clotted lymph. In 1913, E. Steinhardt, C. Israeli, and R. A. Lambert grew vaccinia virus in fragments of guinea pig corneal tiss ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

University Of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. N ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Zena Werb
Zena Werb (24 March 1945 – 16 June 2020) was a professor and the Vice Chair of Anatomy at the University of California, San Francisco. She was also the co-leader of the Cancer, Immunity, and Microenvironment Program at the Hellen Diller Family Comprehensive Cancer Center and a member of the Executive Committee of the Sabre-Sandler Asthma Basic Research Center at UCSF. Her research focused on features of the microenvironment surrounding cells, with particular interest in the extracellular matrix and the role of its protease enzymes in cell signaling. Early life and education Zena Werb was born in Germany in 1945 in the Bergen-Belsen concentration camp (KZ Bergen-Belsen), a few weeks before the camp was liberated. Both of her parents, who were Polish-Jewish, survived the war, with her father having fled to Italy. Her family was able to reunite at a refugee camp in Italy in 1947; they emigrated to Canada in 1948, where Werb was raised on a farm in Ontario. Though her father ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Postdoctoral Fellow
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]