John Kopchick
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John Kopchick
John Kopchick is a molecular biologist and co-inventor of the drug Somavert (Pegvisomant Pegvisomant, sold under the brand name Somavert, is a growth hormone receptor antagonist used in the treatment of acromegaly. It is primarily used if the pituitary gland tumor causing the acromegaly cannot be controlled with surgery or radiatio ...), which has improved the lives of acromegaly, acromegalic individuals around the world. He is currently the Goll-Ohio Eminent Scholar and Professor of Molecular Biology in the Department of Biomedical Sciences at the Ohio University Heritage College of Osteopathic Medicine. Dr. Kopchick's groundbreaking work in the field of growth hormone has helped shape the study of endocrinology. Early life John Joseph Kopchick was born in Punxsutawney, Pennsylvania on November 2, 1950, to Peter Kopchick and Kathryn Gabster Kopchick and spent the first four years of his life with the "groundhog". The family then moved to a small coal-mining town: Ernest, ...
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Punxsutawney, Pennsylvania
Punxsutawney (; Unami language, Lenape: ' ) is a Borough (Pennsylvania), borough in southern Jefferson County, Pennsylvania. Punxsutawney is known globally for its annual Groundhog Day celebration held each February 2, during which thousands of attendees and international media outlets visit the town for an annual weather prediction by the groundhog Punxsutawney Phil, though the actual prediction location, Gobbler's Knob, is actually in adjacent Young Township, Jefferson County, Pennsylvania, Young Township. The borough, located northeast of Pittsburgh and northwest of Altoona, Pennsylvania, Altoona, was incorporated in 1850. With a population of 5,962 as of the 2010 census, Punxsutawney is the largest incorporated municipality in Jefferson County. History Shawnee wigwam villages once occupied this site on the Mahoning Creek. The first settlement that included non-indigenous people was in 1772, when Reverend John Ettwein, a Moravian Church missionary, arrived with a band of 24 ...
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Growth Hormone Receptor
Growth hormone receptor is a protein that in humans is encoded by the ''GHR'' gene. GHR orthologs have been identified in most mammals. Structure Growth hormone receptor (GHR) is a transmembrane protein consisting of 620 amino acids. The receptor is part of the Type I cytokine receptor family of receptors. GHR exists in two forms as a full length membrane-bound receptor and as a soluble GH binding protein (GHBP). GHR contains two fibronectin type III β domains in its extracellular domain, whereas the intracellular domain contains tyrosine Kinase JAK2 binding sites for SH2 proteins. JAK2 is the primary signal transducer for growth hormone. Function This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to reorientation of a pre-assembled receptor dimer dimerization (the receptor may however also exist as monomers on the cell surface ) and the activation of an intra- and intercellular signal transducti ...
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People From Punxsutawney, Pennsylvania
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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Ohio University Faculty
Ohio () is a state in the Midwestern region of the United States. Of the fifty U.S. states, it is the 34th-largest by area, and with a population of nearly 11.8 million, is the seventh-most populous and tenth-most densely populated. The state's capital and largest city is Columbus, with the Columbus metro area, Greater Cincinnati, and Greater Cleveland being the largest metropolitan areas. Ohio is bordered by Lake Erie to the north, Pennsylvania to the east, West Virginia to the southeast, Kentucky to the southwest, Indiana to the west, and Michigan to the northwest. Ohio is historically known as the "Buckeye State" after its Ohio buckeye trees, and Ohioans are also known as "Buckeyes". Its state flag is the only non-rectangular flag of all the U.S. states. Ohio takes its name from the Ohio River, which in turn originated from the Seneca word ''ohiːyo'', meaning "good river", "great river", or "large creek". The state arose from the lands west of the Appalachian Moun ...
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1950 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 '' Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia rises in revolt with Parthian support. Severus marches to Mesopotamia to battle the Parthians. * The Roman province of Syria is divided and the role of Antioch is diminished. The Romans annexed the Syrian cities of Edessa and Nisibis. Severus re-establ ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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21st-century American Biologists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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American Molecular Biologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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University Marketing And Communication
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic Church monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word ''universitas'' (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A ...
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New York College Of Osteopathic Medicine
The New York Institute of Technology College of Osteopathic Medicine (NYIT-COM) is a private medical school located primarily in Old Westbury, New York. It also has a degree-granting campus in Jonesboro, Arkansas. Founded in 1977, NYIT-COM is an academic division of the New York Institute of Technology. Formerly the New York College of Osteopathic Medicine, it is one of the largest medical schools in the United States. History The college opened in 1977, as the first osteopathic medical school in the state of New York, offering the Doctor of Osteopathic Medicine degree (D.O.). The college was established through the efforts of Dr. W. Kenneth Riland, New York State Governor Nelson A. Rockefeller and members of the Rockefeller family. The college was granted accreditation by the American Osteopathic Association (AOA), and was chartered under New York State law through the efforts of Gov. Nelson A. Rockefeller. In 1978, Nelson Rockefeller contributed $250,000 to the college's g ...
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AMVETS
American Veterans (AMVETS) is a non-partisan, volunteer-led organization formed by World War II veterans of the United States military. It advocates for its members as well as for causes that its members deem helpful to the nation at large. The group holds a Federal charter under Title 36 of the United States Code. It is a 501(c)19 organization. History Harold Russell, the handless World War II veteran and Academy Award winner for ''The Best Years of Our Lives'', served three terms as National Commander in the 1950s. As head of AMVETS, Russell wrote to President Harry S. Truman in 1951 supporting his decision to dismiss General Douglas MacArthur during the Korean War. Russell's telegram to Truman cited MacArthur's "repeated insubordination in violation of basic American principles governing civil versus military authority." His telegram said those were "obvious grounds" to relieve MacArthur. Erle Cocke Jr., commander of the American Legion, said that he was "shocked by the n ...
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University Communications And Marketing
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic Church monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word ''universitas'' (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A ...
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