John Crowley (biotech Executive)
John Francis Crowley (born April 7, 1967) is an American biotechnology executive and entrepreneur and the chairman and CEO of Amicus Therapeutics. He co-founded Novazyme Pharmaceuticals with William Canfield, which was later acquired by Genzyme Corporation, and founded Orexigen Therapeutics. In 2006, he was profiled in the book ''The Cure: How a Father Raised $100 Million – And Bucked the Medical Establishment – In a Quest to Save His Children'' by Geeta Anand. In 2010, Crowley released his memoir, ''Chasing Miracles: The Crowley Family Journey of Strength, Hope, and Joy.'' Crowley and his family were the inspiration for the movie ''Extraordinary Measures'' starring Harrison Ford and Brendan Fraser in 2010. Early life and education Crowley was raised in Englewood, New Jersey, the son of an Englewood police officer who died in an accident on duty when Crowley was eight years old.Kerwick, Mike"Archive: Father uses business savvy to fight his kids' rare disease" ''Th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Englewood, New Jersey
Englewood is a city in Bergen County, in the U.S. state of New Jersey, which at the 2020 United States census had a population of 29,308. Englewood was incorporated as a city by an act of the New Jersey Legislature on March 17, 1899, from portions of Ridgefield Township and the remaining portions of Englewood Township.Snyder, John P''The Story of New Jersey's Civil Boundaries: 1606-1968'' Bureau of Geology and Topography; Trenton, New Jersey; 1969. p. 77. Accessed February 14, 2012. History Origin of name Englewood Township, the city's predecessor, is believed to have been named in 1859 for the Engle family. The community had been called the "English Neighborhood", as the first primarily English-speaking settlement on the New Jersey side of the Hudson River after New Netherland was annexed by England in 1664, though other sources mention the Engle family and the heavily forested areas of the community as the derivation of the name. Other sources indicate that the name is de ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brendan Fraser
Brendan James Fraser ( ; born December 3, 1968) is an American-Canadian actor known for his leading roles in blockbusters, comedies, and dramatic films. Having graduated from the Cornish College of the Arts in 1990, he made his film debut in ''Dogfight'' (1991). Fraser had his breakthrough in 1992 with the comedy ''Encino Man'' and the drama ''School Ties''. He gained further prominence for his starring role in ''George of the Jungle'' (1997) and emerged a star playing Rick O'Connell in ''The Mummy'' trilogy (1999–2008). He took on dramatic roles in '' Gods and Monsters'' (1998), ''The Quiet American'' (2002), and ''Crash'' (2004), and further fantasy roles in '' Bedazzled'' (2000) and ''Journey to the Center of the Earth'' (2008). Fraser's film work slowed from the late 2000s to mid 2010s amid various health problems, personal losses, and fallout from a sexual assault allegedly committed against him by Philip Berk, the then-president of the Hollywood Foreign Press Associ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Princeton, New Jersey
Princeton is a municipality with a borough form of government in Mercer County, in the U.S. state of New Jersey. It was established on January 1, 2013, through the consolidation of the Borough of Princeton and Princeton Township, both of which are now defunct. Centrally located within the Raritan Valley region, Princeton is a regional commercial hub for the Central New Jersey region and a commuter town in the New York metropolitan area.New York-Newark, NY-NJ-CT-PA Combined Statistical Area . Accessed December 5, 2020. As of the [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glycogen Storage Disease Type II
Glycogen storage disease type II, also called Pompe disease, is an autosomal recessive metabolic disorder which damages muscle and nerve cells throughout the body. It is caused by an accumulation of glycogen in the lysosome due to deficiency of the lysosomal acid alpha-glucosidase enzyme. It is the only glycogen storage disease with a defect in lysosomal metabolism, and the first glycogen storage disease to be identified, in 1932 by the Dutch pathologist J. C. Pompe. The build-up of glycogen causes progressive muscle weakness (myopathy) throughout the body and affects various body tissues, particularly in the heart, skeletal muscles, liver and the nervous system. Signs and symptoms Newborn The infantile form usually comes to medical attention within the first few months of life. The usual presenting features are cardiomegaly (92%), hypotonia (88%), cardiomyopathy (88%), respiratory distress (78%), muscle weakness (63%), feeding difficulties (57%) and failure to thrive (50%). ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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BusinessWeek
''Bloomberg Businessweek'', previously known as ''BusinessWeek'', is an American weekly business magazine published fifty times a year. Since 2009, the magazine is owned by New York City-based Bloomberg L.P. The magazine debuted in New York City in September 1929. Bloomberg Businessweek business magazines are located in the Bloomberg Tower, 731 Lexington Avenue, Manhattan in New York City and market magazines are located in the Citigroup Center, 153 East 53rd Street between Lexington and Third Avenue, Manhattan in New York City. History ''Businessweek'' was first published based in New York City in September 1929, weeks before the stock market crash of 1929. The magazine provided information and opinions on what was happening in the business world at the time. Early sections of the magazine included marketing, labor, finance, management and Washington Outlook, which made ''Businessweek'' one of the first publications to cover national political issues that directly impacted the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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San Francisco, California
San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and ''Baghdad by the Bay''. San Francisco and the surrounding San Francisco Bay Area are a global center of economic activity and the arts and sciences, spurred ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Master Of Business Administration
A Master of Business Administration (MBA; also Master's in Business Administration) is a postgraduate degree focused on business administration. The core courses in an MBA program cover various areas of business administration such as accounting, applied statistics, human resources, business communication, business ethics, business law, strategic management, business strategy, finance, managerial economics, management, entrepreneurship, marketing, supply-chain management, and operations management in a manner most relevant to management analysis and strategy. It originated in the United States in the early 20th century when the country industrialized and companies sought scientific management. Some programs also include elective courses and concentrations for further study in a particular area, for example, accounting, finance, marketing, and human resources, but an MBA is intended to be a generalized program. MBA programs in the United States typically require completing ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Indianapolis, Indiana
Indianapolis (), colloquially known as Indy, is the state capital and most populous city of the U.S. state of Indiana and the seat of Marion County. According to the U.S. Census Bureau, the consolidated population of Indianapolis and Marion County was 977,203 in 2020. The "balance" population, which excludes semi-autonomous municipalities in Marion County, was 887,642. It is the 15th most populous city in the U.S., the third-most populous city in the Midwest, after Chicago and Columbus, Ohio, and the fourth-most populous state capital after Phoenix, Arizona, Austin, Texas, and Columbus. The Indianapolis metropolitan area is the 33rd most populous metropolitan statistical area in the U.S., with 2,111,040 residents. Its combined statistical area ranks 28th, with a population of 2,431,361. Indianapolis covers , making it the 18th largest city by land area in the U.S. Indigenous peoples inhabited the area dating to as early as 10,000 BC. In 1818, the Lenape relinquishe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Notre Dame
The University of Notre Dame du Lac, known simply as Notre Dame ( ) or ND, is a private Catholic research university in Notre Dame, Indiana, outside the city of South Bend. French priest Edward Sorin founded the school in 1842. The main campus covers 1,261 acres (510 ha) in a suburban setting and contains landmarks such as the Golden Dome, the ''Word of Life'' mural (commonly known as ''Touchdown Jesus''), Notre Dame Stadium, and the Basilica. Originally for men, although some women earned degrees in 1918, the university began formally accepting undergraduate female students in 1972. Notre Dame has been recognized as one of the top universities in the United States. The university is organized into seven schools and colleges. Notre Dame's graduate program includes more than 50 master, doctoral and professional degrees offered by the six schools, including the Notre Dame Law School and an MD–PhD program offered in combination with the Indiana University School of Medicine ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Georgetown University
Georgetown University is a private university, private research university in the Georgetown (Washington, D.C.), Georgetown neighborhood of Washington, D.C. Founded by Bishop John Carroll (archbishop of Baltimore), John Carroll in 1789 as Georgetown College (Georgetown University), Georgetown College, the university has grown to comprise eleven Undergraduate education, undergraduate and Postgraduate education, graduate schools, including the School of Foreign Service, Walsh School of Foreign Service, McDonough School of Business, Georgetown University School of Medicine, Medical School, Georgetown University Law Center, Law School, and a Georgetown University in Qatar, campus in Qatar. The school's main campus, on a hill above the Potomac River, is identifiable by its flagship Healy Hall, a National Historic Landmark. The school was founded by and is affiliated with the Society of Jesus, and is the oldest Catholic institution of higher education in the United States, though the m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Asbury Park Press
The ''Asbury Park Press'' is a daily newspaper in Monmouth and Ocean counties of New Jersey and has the third largest circulation in the state. It has been owned by Gannett since 1997. Its reporting staff has been awarded numerous national honors in journalism, including the Selden Ring Award for Investigative Reporting, two the Associated Press Managing Editors' Award for Public Service, the National Headliner Award for Public Service and two National Headliner Awards for Best Series (large papers). The ''Press'' investigative team was a finalist for the 2010 Pulitzer Prize in Public Service. The newspaper was also the home to editorial cartoonist Steve Breen when he won the Pulitzer Prize in that category in 1998. Awards The Asbury Park Press has a history of winning national awards for its public service and investigative reporting. Its editorial cartoonist Steve Breen won the Pulitzer Prize for Editorial Cartooning The Pulitzer Prize for Illustrated Reporting and Comm ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oradell, New Jersey
Oradell is a Borough (New Jersey), borough in Bergen County, New Jersey, Bergen County, New Jersey, United States. As of the 2020 United States Census, the borough's population was 8,244,, an increase of 266 from the 2010 United States census, 2010 census count of 7,978.DP-1 - Profile of General Population and Housing Characteristics: 2010 for Oradell borough, Bergen County, New Jersey , United States Census Bureau. Accessed March 11, 2013.Profile of Gene ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |