John Brownlee (statistician)
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John Brownlee (statistician)
John Brownlee (1868–1927) was a British physician and medical statistician who became the first director of the Statistics Department of the UK's Medical Research Committee. Life The son of a Church of Scotland minister, he studied at the University of Glasgow, obtaining degrees first in mathematics and natural philosophy and then in medicine. He became in 1900 physician-superintendent to the City of Glasgow Fever Hospital. In 1914 he became the founding director of the statistics department of the UK Medical Research Committee and held the post until his sudden death from bronchopneumonia in 1927. Works Brownlee was influenced by Karl Pearson's mathematical approach to statistics, and applied the Pearson family of distributions to epidemics. In the view of fellow epidemiologist and statistician Major Greenwood, Brownlee took these techniques further than any of his contemporaries. His studies included the epidemiology of phthisis and measles Measles is a highly c ...
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Medical Statistics
Medical statistics deals with applications of statistics to medicine and the health sciences, including epidemiology, public health, forensic medicine, and clinical research. Medical statistics has been a recognized branch of statistics in the United Kingdom for more than 40 years but the term has not come into general use in North America, where the wider term 'biostatistics' is more commonly used.Dodge, Y. (2003) ''The Oxford Dictionary of Statistical Terms'', OUP. However, "biostatistics" more commonly connotes all applications of statistics to biology. Medical statistics is a subdiscipline of statistics. "It is the science of summarizing, collecting, presenting and interpreting data in medical practice, and using them to estimate the magnitude of associations and test hypotheses. It has a central role in medical investigations. It not only provides a way of organizing information on a wider and more formal basis than relying on the exchange of anecdotes and personal experien ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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Church Of Scotland
The Church of Scotland ( sco, The Kirk o Scotland; gd, Eaglais na h-Alba) is the national church in Scotland. The Church of Scotland was principally shaped by John Knox, in the Scottish Reformation, Reformation of 1560, when it split from the Catholic Church and established itself as a church in the reformed tradition. The church is Calvinist Presbyterian, having no head of faith or leadership group and believing that God invited the church's adherents to worship Jesus. The annual meeting of its general assembly is chaired by the Moderator of the General Assembly of the Church of Scotland. The Church of Scotland celebrates two sacraments, Baptism and the Lord's Supper in Reformed theology, Lord's Supper, as well as five other Rite (Christianity), rites, such as Confirmation and Christian views on marriage, Matrimony. The church adheres to the Bible and the Westminster Confession of Faith, and is a member of the World Communion of Reformed Churches. History Presbyterian tra ...
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University Of Glasgow
, image = UofG Coat of Arms.png , image_size = 150px , caption = Coat of arms Flag , latin_name = Universitas Glasguensis , motto = la, Via, Veritas, Vita , mottoeng = The Way, The Truth, The Life , established = , type = Public research universityAncient university , endowment = £225.2 million , budget = £809.4 million , rector = Rita Rae, Lady Rae , chancellor = Dame Katherine Grainger , principal = Sir Anton Muscatelli , academic_staff = 4,680 (2020) , administrative_staff = 4,003 , students = () , undergrad = () , postgrad = () , city = Glasgow , country = Scotland, UK , colours = , website = , logo ...
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Natural Philosophy
Natural philosophy or philosophy of nature (from Latin ''philosophia naturalis'') is the philosophical study of physics Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which r ..., that is, nature and the physical universe. It was dominant before the development of modern science. From the ancient world (at least since Aristotle) until the 19th century, ''natural philosophy'' was the common term for the study of physics (nature), a broad term that included botany, zoology, anthropology, and chemistry as well as what we now call physics. It was in the 19th century that the concept of science received its modern shape, with different subjects within science emerging, such as astronomy, biology, and physics. Institutions and communities devoted to science were founded. Isaac Newton's book ...
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Bronchopneumonia
Bronchopneumonia is a subtype of pneumonia. It is the acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs. citing: Webster's New World College Dictionary, Fifth Edition, Copyright 2014 It is often contrasted with lobar pneumonia; but, in clinical practice, the types are difficult to apply, as the patterns usually overlap. Topic Completed: 1 August 2011 Bronchopneumonia (lobular) often leads to lobar pneumonia as the infection progresses. The same organism may cause one type of pneumonia in one patient, and another in a different patient. Causes Bronchopneumonia is usually a bacterial pneumonia rather than being caused by viral disease. Medically reviewed by Gerhard Whitworth, RN, on April 19, 2019 It is more commonly a hospital-acquired pneumonia than a community-acquired pneumonia, in contrast to lobar pneumonia. Bronchopneumonia is less likely than lobar pneumonia to be associated with ''Streptococcus pneumoniae''. Rather, t ...
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International Journal Of Epidemiology
The ''International Journal of Epidemiology'' is a bimonthly peer-reviewed medical journal covering research in epidemiology. It is the official journal of the International Epidemiological Association and is published by Oxford University Press. The journal is a member of the Committee on Publication Ethics. The editor-in-chief is Stephen Leeder (University of Sydney). History The journal was established in 1972 by the International Epidemiological Association to facilitate communication among its members and all those engaged in research, teaching and the application of epidemiology. The first editor-in-chief, Walter W. Holland, hoped to "overcome some of the problems of publication of epidemiological work in local journals, which often tend to be unavailable to workers outside that country" and to "create an international viewpoint of health problems." Editors The following persons are or have been editors-in-chief: *1972–1977: Walter W. Holland *1978–1981: A.E. Bennett ...
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Karl Pearson
Karl Pearson (; born Carl Pearson; 27 March 1857 – 27 April 1936) was an English mathematician and biostatistician. He has been credited with establishing the discipline of mathematical statistics. He founded the world's first university statistics department at University College, London in 1911, and contributed significantly to the field of biometrics and meteorology. Pearson was also a proponent of social Darwinism, eugenics and scientific racism. Pearson was a protégé and biographer of Sir Francis Galton. He edited and completed both William Kingdon Clifford's ''Common Sense of the Exact Sciences'' (1885) and Isaac Todhunter's ''History of the Theory of Elasticity'', Vol. 1 (1886–1893) and Vol. 2 (1893), following their deaths. Biography Pearson was born in Islington, London into a Quaker family. His father was William Pearson QC of the Inner Temple, and his mother Fanny (née Smith), and he had two siblings, Arthur and Amy. Pearson attended University College Scho ...
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Pearson Distribution
The Pearson distribution is a family of continuous probability distribution, continuous probability distributions. It was first published by Karl Pearson in 1895 and subsequently extended by him in 1901 and 1916 in a series of articles on biostatistics. History The Pearson system was originally devised in an effort to model visibly skewness, skewed observations. It was well known at the time how to adjust a theoretical model to fit the first two cumulants or moment (mathematics), moments of observed data: Any probability distribution can be extended straightforwardly to form a location-scale family. Except in pathological (mathematics), pathological cases, a location-scale family can be made to fit the observed mean (mathematics), mean (first cumulant) and variance (second cumulant) arbitrarily well. However, it was not known how to construct probability distributions in which the skewness (standardized third cumulant) and kurtosis (standardized fourth cumulant) could be adjuste ...
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Epidemic
An epidemic (from Ancient Greek, Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics of infectious diseases are generally caused by several factors including a significant change in the ecology of the areal population (e.g., increased stress maybe additional reason or increase in the density of a vector species), the introduction of an emerging pathogen to an areal population (by movement of pathogen or host) or an unexpected genetic change that is in the pathogen reservoir. Generally, epidemics concerns with the patterns of infectious disease spread. An epidemic may occur when host immunity to either an established pathogen or newly emerging novel pathogen is suddenly reduced below that found in the endemic equilibrium and the transmission threshold is exceeded. For example, in meningococcal infections, an attack rate in ...
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Major Greenwood
Major Greenwood FRS (9 August 1880 – 5 October 1949) was an English epidemiologist and statistician. Biography Major Greenwood junior was born in Shoreditch in London's East End, the only child of Major Greenwood, a physician in general practice there ("Major" was his forename, not a military rank.) and his wife Annie, daughter of Peter Lodwick Burchell, F.R.C.S., M.B., L.S.A.Burke's Landed Gentry, 18th ed., vol. I, 1965, pg 338-343, 'Greenwood formerly of Haddenham' pedigree The Greenwood family is recorded back to the twelfth century in the person of Wyomarus Greenwode, of Greenwode Leghe, near Heptonstall, Yorkshire, caterer to the Empress Maude in 1154. Greenwood was educated on the classical side at Merchant Taylors' School and went on to study medicine at University College London and the London Hospital. On qualifying in 1904 he worked for a time as assistant to his father but after a few months he gave up clinical practice for good. He went to work as a demonstr ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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