Johann Florian Heller
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Johann Florian Heller
Johann Florian Heller (4 May 1813 – 21 November 1871) was an Austrian chemist who was one of the founders of clinical chemistry. Heller was born in Vienna, Austria. He studied chemistry in Prague and later with Liebig and Wöhler at Giessen. Louis Rosenfeld (1999), ''Four centuries of clinical chemistry''. CRC PressOnline versionaccessed on 2009-07-30. Giuliano dall'Olio (2008), ''Nuovo componente dei calcoli vescicali — L’ “urostealite ” di Heller''. RIMeL - IJLaM, volume 4, issue 1, Società Italiana Medicina di Laboratorio. During those studies he characterized rhodizonic acid and its potassium salt (1837). Johann Florian Heller (1837), ''Die Rhodizonsäure, eine aus den Produkten der Kaliumbereitung gewonnene neue Säure, und ihre chemischen Verhältnisse'', Justus Liebigs Annalen der Pharmacie, volume 24, issue 1, pp. 1–16Online versionaccessed on 2009-07-08. In 1844 Heller established a laboratory of pathological chemistry in Vienna's General Hospital ...
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Johann Florian Heller
Johann Florian Heller (4 May 1813 – 21 November 1871) was an Austrian chemist who was one of the founders of clinical chemistry. Heller was born in Vienna, Austria. He studied chemistry in Prague and later with Liebig and Wöhler at Giessen. Louis Rosenfeld (1999), ''Four centuries of clinical chemistry''. CRC PressOnline versionaccessed on 2009-07-30. Giuliano dall'Olio (2008), ''Nuovo componente dei calcoli vescicali — L’ “urostealite ” di Heller''. RIMeL - IJLaM, volume 4, issue 1, Società Italiana Medicina di Laboratorio. During those studies he characterized rhodizonic acid and its potassium salt (1837). Johann Florian Heller (1837), ''Die Rhodizonsäure, eine aus den Produkten der Kaliumbereitung gewonnene neue Säure, und ihre chemischen Verhältnisse'', Justus Liebigs Annalen der Pharmacie, volume 24, issue 1, pp. 1–16Online versionaccessed on 2009-07-08. In 1844 Heller established a laboratory of pathological chemistry in Vienna's General Hospital ...
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Pathological Chemistry
Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes. It is an applied form of biochemistry (not to be confused with medicinal chemistry, which involves basic research for drug development). The discipline originated in the late 19th century with the use of simple chemical reaction tests for various components of blood and urine. In the many decades since, other techniques have been applied as science and technology have advanced, including the use and measurement of enzyme activities, spectrophotometry, electrophoresis, and immunoassay. There are now many blood tests and clinical urine tests with extensive diagnostic capabilities. Most current laboratories are now highly automated to accommodate the high workload typical of a hospital laboratory. Tests performed are closely monitored and quality contro ...
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1813 Births
Events January–March * January 18–January 23 – War of 1812: The Battle of Frenchtown is fought in modern-day Monroe, Michigan between the United States and a British and Native American alliance. * January 24 – The Philharmonic Society (later the Royal Philharmonic Society) is founded in London. * January 28 – Jane Austen's '' Pride and Prejudice'' is published anonymously in London. * January 31 – The Assembly of the Year XIII is inaugurated in Buenos Aires. * February – War of 1812 in North America: General William Henry Harrison sends out an expedition to burn the British vessels at Fort Malden by going across Lake Erie via the Bass Islands in sleighs, but the ice is not hard enough, and the expedition returns. * February 3 – Argentine War of Independence: José de San Martín and his Regiment of Mounted Grenadiers gain a largely symbolic victory against a Spanish royalist army in the Battle of San Lorenzo. * February ...
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Austrian Association For Clinical Chemistry
Austrian may refer to: * Austrians, someone from Austria or of Austrian descent ** Someone who is considered an Austrian citizen, see Austrian nationality law * Austrian German dialect * Something associated with the country Austria, for example: ** Austria-Hungary ** Austrian Airlines (AUA) ** Austrian cuisine ** Austrian Empire ** Austrian monarchy ** Austrian German (language/dialects) ** Austrian literature ** Austrian nationality law ** Austrian Service Abroad ** Music of Austria **Austrian School of Economics * Economists of the Austrian school of economic thought * The Austrian Attack variation of the Pirc Defence chess opening. See also * * * Austria (other) * Australian (other) * L'Autrichienne (other) is the feminine form of the French word , meaning "The Austrian". It may refer to: *A derogatory nickname for Queen Marie Antoinette of France *L'Autrichienne (film), ''L'Autrichienne'' (film), a 1990 French film on Marie Antoinette w ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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Sodium Carbonate
Sodium carbonate, , (also known as washing soda, soda ash and soda crystals) is the inorganic compound with the formula Na2CO3 and its various hydrates. All forms are white, odourless, water-soluble salts that yield moderately alkaline solutions in water. Historically, it was extracted from the ashes of plants growing in sodium-rich soils. Because the ashes of these sodium-rich plants were noticeably different from ashes of wood (once used to produce potash), sodium carbonate became known as "soda ash". It is produced in large quantities from sodium chloride and limestone by the Solvay process. Hydrates Sodium carbonate is obtained as three hydrates and as the anhydrous salt: * sodium carbonate decahydrate (natron), Na2CO3·10H2O, which readily efflorescence, effloresces to form the monohydrate. * sodium carbonate heptahydrate (not known in mineral form), Na2CO3·7H2O. * sodium carbonate monohydrate (thermonatrite), Na2CO3·H2O. Also known as crystal carbonate. * anhydrous sodium ...
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Bladder Stone
A bladder stone is a stone found in the urinary bladder. Signs and symptoms Bladder stones are small mineral deposits that can form in the bladder. In most cases bladder stones develop when the urine becomes very concentrated or when one is dehydrated. This allows for minerals, such as calcium or magnesium salts, to crystallize and form stones. Bladder stones vary in number, size and consistency. In some cases bladder stones do not cause any symptoms and are discovered as an incidental finding on a plain radiograph. However, when symptoms do occur, these may include severe lower abdominal and back pain, difficult urination, frequent urination at night, fever, painful urination and blood in the urine. The majority of individuals who are symptomatic will complain of pain which comes in waves. The pain may also be associated with nausea, vomiting and chills.
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Urostealith
Urostealith is a fatty or resinous substance identified by the Austrian chemist J. F. Heller in 1845 as the main constituent of some bladder stones. Giuliano dall'Olio (2008), ''Nuovo componente dei calcoli vescicali — L’ “urostealite ” di Heller''. (In Italian) RIMeL - IJLaM, volume 4, issue 1, Società Italiana Medicina di LaboratorioOnline versionaccessed on 2009-07-30. According to Heller's and other contemporary descriptions, urostealith is a soft brown substance, insoluble in water, sparingly soluble in alcohol and easily soluble in ether. Upon heating it softens at first, then expands and carbonizes before melting. It dissolves in solutions of sodium carbonate, and the latter was successfully used by Heller to dissolve and break up stones in a patient's bladder. Urostealith stones seem to be very rare. S. Materazzi, R. Curini, G. D'Ascenzo, and A. D. Magri (1995), ''TG-FTIR coupled analysis applied to the studies in urolithiasis: characterization of human renal ...
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Albumin
Albumin is a family of globular proteins, the most common of which are the serum albumins. All the proteins of the albumin family are water-soluble, moderately soluble in concentrated salt solutions, and experience heat denaturation. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Substances containing albumins are called ''albuminoids''. A number of blood transport proteins are evolutionarily related in the albumin family, including serum albumin, alpha-fetoprotein, vitamin D-binding protein and afamin. This family is only found in vertebrates. ''Albumins'' in a less strict sense can mean other proteins that coagulate under certain conditions. See for lactalbumin, ovalbumin and plant "2S albumin". Function Albumins in general are transport proteins that bind to various ligands and carry them around. Human types include: * Human serum albumin is the main protein of human blood plasma. It makes up around 50 ...
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Heller's Test
Heller's test is a chemical test that shows that strong acids cause the denaturation of precipitated proteins. Concentrated nitric acid is added to a protein solution from the side of the test tube to form two layers. A white ring appears between the two layers if the test is positive. Heller's test is commonly used to test for the presence of proteins in urine. This test was discovered by the Austrian Chemist, Johann Florian Heller Johann Florian Heller (4 May 1813 – 21 November 1871) was an Austrian chemist who was one of the founders of clinical chemistry. Heller was born in Vienna, Austria. He studied chemistry in Prague and later with Liebig and Wöhler at Giessen. ... (1813-1871). References Chemical tests {{analytical-chemistry-stub ...
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Urine
Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excretion, excreted from the body through the urethra. Cell (biology), Cellular metabolism generates many by-products that are rich in nitrogen and must be clearance (medicine), cleared from the Circulatory system, bloodstream, such as urea, uric acid, and creatinine. These by-products are expelled from the body during urination, which is the primary method for excreting water-soluble chemicals from the body. A urinalysis can detect nitrogenous wastes of the mammalian body. Urine plays an important role in the earth's nitrogen cycle. In balanced ecosystems, urine fertilizes the soil and thus helps plants to grow. Therefore, Reuse of excreta, urine can be used as a fertilizer. Some animals use it to territory (animal)#Scent marking, mark their territories. Historically, aged or fermented urine (kn ...
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Salt (chemistry)
In chemistry, a salt is a chemical compound consisting of an ionic assembly of positively charged cations and negatively charged anions, which results in a compound with no net electric charge. A common example is table salt, with positively charged sodium ions and negatively charged chloride ions. The component ions in a salt compound can be either inorganic, such as chloride (Cl−), or organic, such as acetate (). Each ion can be either monatomic, such as fluoride (F−), or polyatomic, such as sulfate (). Types of salt Salts can be classified in a variety of ways. Salts that produce hydroxide ions when dissolved in water are called ''alkali salts'' and salts that produce hydrogen ions when dissolved in water are called ''acid salts''. ''Neutral salts'' are those salts that are neither acidic nor basic. Zwitterions contain an anionic and a cationic centre in the same molecule, but are not considered salts. Examples of zwitterions are amino acids, many metabolites, peptid ...
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