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Jingmenvirus
Jingmenvirus is a group of positive-sense single-stranded RNA viruses with segmented genomes. They are primarily associated with arthropods and are one of only two known segmented RNA viruses that infect animal hosts. The first member of the group, the Jingmen tick virus (JMTV), was described in 2014. Another member, the Guaico Culex virus (GCXV), has a highly unusual multicomponent architecture in which the genome segments are separately enclosed in different viral capsids. Examples Jingmen tick virus The first member of the group was described in 2014 and named the Jingmen tick virus (JMTV) because it was isolated from a tick sampled in Jingmen, China. It is an enveloped spherical virus slightly larger than its closest viral relatives. The JMTV genome has four segments, two of which contain genes with sequence homology to non-structural proteins found in flaviviruses, including methyltransferase and RNA-dependent RNA polymerase. The putative structural proteins in the JMTV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guaico Culex Virus
Jingmenvirus is a group of positive-sense single-stranded RNA viruses with segmented genomes. They are primarily associated with arthropods and are one of only two known segmented RNA viruses that infect animal hosts. The first member of the group, the Jingmen tick virus (JMTV), was described in 2014. Another member, the Guaico Culex virus (GCXV), has a highly unusual multicomponent architecture in which the genome segments are separately enclosed in different viral capsids. Examples Jingmen tick virus The first member of the group was described in 2014 and named the Jingmen tick virus (JMTV) because it was isolated from a tick sampled in Jingmen, China. It is an enveloped spherical virus slightly larger than its closest viral relatives. The JMTV genome has four segments, two of which contain genes with sequence homology to non-structural proteins found in flaviviruses, including methyltransferase and RNA-dependent RNA polymerase. The putative structural proteins in the JMTV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jingmen Tick Virus
Jingmen () is a prefecture-level city in central Hubei province, People's Republic of China. Jingmen is within an area where cotton and oil crops are planted. The population of the prefecture is 2,873,687 (2010 population census). The urban area of Jingmen City has a population of about 400,000. Jingmen is so named as in ancient times it was the gateway to Jingzhou, one of the Nine Provinces and means literally ''Gateway to Jingzhou''. During the Second World War, the city was occupied by Japanese forces. Administrative divisions Jingmen municipality comprises two districts, two county-level cities, one county and three other non MoCA management areas: * Dongbao District () * Duodao District () * Zhongxiang city () * Jingshan city () * Shayang County () * Jingmen Advanced Technology Area ( or ) * Zhanghe New Area () * Qujialing Management District () City layout Dongbao District "downtown" is located about 3 hours away from Wuhan by bus or rail. A new train service ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jingmen
Jingmen () is a prefecture-level city in central Hubei province, People's Republic of China. Jingmen is within an area where cotton and oil crops are planted. The population of the prefecture is 2,873,687 (2010 population census). The urban area of Jingmen City has a population of about 400,000. Jingmen is so named as in ancient times it was the gateway to Jingzhou, one of the Nine Provinces and means literally ''Gateway to Jingzhou''. During the Second World War, the city was occupied by Japanese forces. Administrative divisions Jingmen municipality comprises two districts, two county-level cities, one county and three other non MoCA management areas: * Dongbao District () * Duodao District () * Zhongxiang city () * Jingshan city () * Shayang County () * Jingmen Advanced Technology Area ( or ) * Zhanghe New Area () * Qujialing Management District () City layout Dongbao District "downtown" is located about 3 hours away from Wuhan by bus or rail. A new train service wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protease
A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes (increases reaction rate or "speeds up") proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. They do this by cleaving the peptide bonds within proteins by hydrolysis, a reaction where water breaks bonds. Proteases are involved in many biological functions, including digestion of ingested proteins, protein catabolism (breakdown of old proteins), and cell signaling. In the absence of functional accelerants, proteolysis would be very slow, taking hundreds of years. Proteases can be found in all forms of life and viruses. They have independently evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms. Hierarchy of proteases Based on catalytic residue Proteases can be classified into seven broad groups: * Serine protease ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Reading Frame
In molecular biology, open reading frames (ORFs) are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its subsequent interaction with the ribosome in translation). Such an ORF may contain a start codon (usually AUG in terms of RNA) and by definition cannot extend beyond a stop codon (usually UAA, UAG or UGA in RNA). That start codon (not necessarily the first) indicates where translation may start. The transcription termination site is located after the ORF, beyond the translation stop codon. If transcription were to cease before the stop codon, an incomplete protein would be made during translation. In eukaryotic genes with multiple exons, introns are removed and exons are then joined together after transcription to yield the final ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental or clinical samples by a method called sequencing. The broad field may also be referred to as environmental genomics, ecogenomics, community genomics or microbiomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primate
Primates are a diverse order of mammals. They are divided into the strepsirrhines, which include the lemurs, galagos, and lorisids, and the haplorhines, which include the tarsiers and the simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the 2010s, and three in the 2020s. Primates have large bra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Colobus Monkey
Red colobuses are Old World monkeys of the genus ''Piliocolobus''. It was formerly considered a subgenus within the genus ''Procolobus'', which is now restricted to the olive colobus. They are closely related to the black-and-white colobus monkeys (genus ''Colobus''), and some species are often found in groups with the blue monkey. The western red colobus is frequently hunted by the common chimpanzee. The members of this genus are found in western, central and eastern Africa, and the species have largely allopatric, allo- or parapatric distributions. They are primarily arboreal and most are restricted to humid forests, but the Zanzibar red colobus prefers coastal thickets and scrub. Red colobuses are highly sensitive to hunting and habitat destruction, and have been referred to as probably the most threatened Taxonomy (biology), taxonomic group of primates in Africa. If following the taxonomic treatment advocated in ''Mammal Species of the World'', all species except the Udzungwa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxocara Canis
''Toxocara canis'' (also known as dog roundworm) is a worldwide-distributed helminth parasite of dogs and other canids. The name is derived from the Greek word "," meaning bow or quiver, and the Latin word "caro," meaning flesh.Bassert , J., & Thomas, J. (2014). McCurnin's Clinical Textbook for Veterinary Technicians. (8th ed.). St. Louis , MO: Elsevier They live in the small intestine of the definitive host. In adult dogs, the infection is usually asymptomatic but may be characterized by diarrhea. By contrast, massive infection with ''Toxocara canis'' can be fatal in puppies, causing diarrhea, vomiting, an enlarged abdomen, flatulence, and poor growth rate. As paratenic hosts, a number of vertebrates, including humans, and some invertebrates can become infected. Humans are infected, like other paratenic hosts, by ingestion of embryonated ''T. canis'' eggs. The disease (toxocariasis) caused by migrating ''T. canis'' larvae results in two syndromes: visceral larva migrans and ocu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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