Jeffrey Wigand
Jeffrey Stephen Wigand (; born December 17, 1942) is an American biochemist and whistleblower. He is a former vice president of research and development at Brown & Williamson in Louisville, Kentucky, who worked on the development of reduced-harm cigarettes and in 1996 blew the whistle on tobacco tampering at the company. This was adapted for 1999 film '' The Insider'', with Russell Crowe portraying Wigand. He currently lectures around the world as an expert witness and consultant for various tobacco issues. Early life, military service and education Wigand was born in New York City and grew up in the Bronx and later Pleasant Valley, New York. After a brief time in the military (including a short assignment in Vietnam), he earned a Master's in Biochemistry and a PhD from the University at Buffalo in Biochemistry. Career Prior to working for Brown & Williamson, Wigand worked for several health care companies, including Pfizer and Johnson & Johnson. In addition, he was employed ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Whistleblower
A whistleblower (also written as whistle-blower or whistle blower) is a person, often an employee, who reveals information about activity within a private or public organization that is deemed illegal, immoral, illicit, unsafe or fraudulent. Whistleblowers can use a variety of internal or external channels to communicate information or allegations. Over 83% of whistleblowers report internally to a supervisor, human resources, compliance, or a neutral third party within the company, hoping that the company will address and correct the issues. A whistleblower can also bring allegations to light by communicating with external entities, such as the media, government, or law enforcement. Whistleblowing can occur in either the private sector or the public sector. Retaliation is a real risk for whistleblowers, who often pay a heavy price for blowing the whistle. The most common form of retaliation is abrupt termination of employment. However, several other actions may also be conside ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891). Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 64th on the Fortune 500 and 49th on the Forbes Global 2000. History 1849–1950: Early history Pfizer was founded in 1849 by Charles Pfizer and Charles F. Erhart, two cousins who ha ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Michael Mann (film Director)
Michael Kenneth Mann (born February 5, 1943) is an American director, screenwriter, and producer of film and television who is best known for his distinctive style of crime drama. His most acclaimed works include the films '' Thief'' (1981), '' Manhunter'' (1986), ''The Last of the Mohicans'' (1992), ''Heat'' (1995), '' The Insider'' (1999), ''Collateral'' (2004), and '' Public Enemies'' (2009). He is also known for his role as executive producer on the popular TV series ''Miami Vice'' (1984–89), which he adapted into a 2006 feature film. For his work, he has received nominations from international organizations and juries, including the British Academy of Film and Television Arts, Cannes, and the Academy of Motion Picture Arts and Sciences. As a producer, Mann has twice received nominations for the Academy Award for Best Picture, first for ''The Insider'' and then '' The Aviator'' (2004), which Mann had been hired to direct before the project was transferred to Martin Sco ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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DuPont Manual Magnet High School
duPont Manual High School is a public magnet high school located in the Old Louisville neighborhood of Louisville, Kentucky, United States. It serves students in grades 9– 12. It is a part of the Jefferson County Public School District. DuPont Manual is recognized by the United States Department of Education as a Blue Ribbon School. Manual opened in 1892 as an all-male manual training school. It was the second public high school in Louisville. Manual merged with its rival, Male High School, into a consolidated school from 1915 to 1919. Manual permanently merged with the Louisville Girls High School in 1950 and moved into their Gothic-style three-story building, built in 1934. In 2004, after conducting a poll, Louisville's ''Courier-Journal'' newspaper listed Manual as one of Louisville residents' ten favorite buildings. Manual experienced a decline in discipline and test scores in the 1970s. In 1984, Manual became a magnet school, allowing students from throughout the distri ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Investigative Group International
Terry Falk Lenzner (August 10, 1939 – April 23, 2020) was an American attorney and founder of Investigative Group International. Biography Lenzner was born in Manhattan, the son of Eleanor (Falk), a homemaker, and Joseph Lenzner, a dentist. His paternal grandparents were from Lithuania. He was raised in a secular American Jews, Jewish family in Manhattan and attended Philips Exeter Academy. He graduated with a B.A. from Harvard University, where he was captain of the football team in 1960, and with a J.D. from Harvard Law School. After school in 1964, following the advice of attorney Lloyd K. Garrison, he worked for the civil rights division of the Justice Department where he investigated the murders of Murders of Chaney, Goodman, and Schwerner, three civil rights workers in Mississippi. He then worked as an assistant U.S. attorney under Bob Morgenthau in the organized crime unit in New York before becoming the director of the federal office of Legal Services in the Richard Nix ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Coumarin
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It can be placed in the benzopyrone chemical class and considered as a lactone. Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. By inhibiting synthesis of vitamin K, a related compound is used as the prescription drug warfarin – an anticoagulant – to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism. Etymology Coumarin is derived from ''coumarou'', the French word for the tonka bean. The word ''tonka'' for the tonka bean is taken from the Galibi (Carib) tongue spoken by natives of French Gui ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Carcinogenic
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise from both natural and synthetic substances. Carcinogens are not necessarily immediately toxic; thus, their effect can be insidious. Carcinogens, as mentioned, are agents in the environment capable of contributing to cancer growth. Carcinogens can be categorized into two different types: activation-dependent and activation-independent, and each nature impacts their l ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Death Threat
A death threat is a threat, often made anonymously, by one person or a group of people to kill another person or group of people. These threats are often designed to intimidate victims in order to manipulate their behaviour, in which case a death threat could be a form of coercion. For example, a death threat could be used to dissuade a public figure from pursuing a criminal investigation or an advocacy campaign. Legality In most jurisdictions, death threats are a serious type of criminal offence. Death threats are often covered by coercion statutes. For instance, the coercion statute in Alaska says: Methods A death threat can be communicated via a wide range of media, among these letters, newspaper publications, telephone calls, internet blogs and e-mail. If the threat is made against a political figure, it can also be considered treason. If a threat targets a location that is frequented by people (e.g. a building), it could be a terrorist threat. Sometimes, death threa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harassment
Harassment covers a wide range of behaviors of offensive nature. It is commonly understood as behavior that demeans, humiliates or embarrasses a person, and it is characteristically identified by its unlikelihood in terms of social and moral reasonableness. In the legal sense, these are behaviors that appear to be disturbing, upsetting or threatening. Traditional forms evolve from discriminatory grounds, and have an effect of nullifying a person's rights or impairing a person from benefiting from their rights. When these behaviors become repetitive, it is defined as bullying. The continuity or repetitiveness and the aspect of distressing, alarming or threatening may distinguish it from insult. Etymology Attested in English from 1753, ''harassment'' derives from the English verb ''harass'' plus the suffix ''-ment''. The verb ''harass'', in turn, is a loan word from the French, which was already attested in 1572 meaning ''torment, annoyance, bother, trouble'' and later as of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nicotine
Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve drug withdrawal, withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist. Nicotine constitutes approximately 0.6–3.0% of the dry weight of tobacco. Nicotine is also present at Parts-per notation, ppb-concentrations in edible plants in the family Solanaceae, including potatoes, tomatoes, and eggplants, though sources disagree on whether this has any biological significance to human consumers. It functions as an plant defense against herbivory, antiherbivore toxin; consequently, nicotine was widely used as an insectic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ammonia
Ammonia is an inorganic compound of nitrogen and hydrogen with the formula . A stable binary hydride, and the simplest pnictogen hydride, ammonia is a colourless gas with a distinct pungent smell. Biologically, it is a common nitrogenous waste, particularly among aquatic organisms, and it contributes significantly to the nutritional needs of terrestrial organisms by serving as a precursor to 45% of the world's food and fertilizers. Around 70% of ammonia is used to make fertilisers in various forms and composition, such as urea and Diammonium phosphate. Ammonia in pure form is also applied directly into the soil. Ammonia, either directly or indirectly, is also a building block for the synthesis of many pharmaceutical products and is used in many commercial cleaning products. It is mainly collected by downward displacement of both air and water. Although common in nature—both terrestrially and in the outer planets of the Solar System—and in wide use, ammonia is bot ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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60 Minutes
''60 Minutes'' is an American television news magazine broadcast on the CBS television network. Debuting in 1968, the program was created by Don Hewitt and Bill Leonard, who chose to set it apart from other news programs by using a unique style of reporter-centered investigation. In 2002, ''60 Minutes'' was ranked number six on ''TV Guide''s list of the " 50 Greatest TV Shows of All Time", and in 2013, it was ranked number 24 on the magazine's list of the "60 Best Series of All Time". ''The New York Times'' has called it "one of the most esteemed news magazines on American television". Originally airing in 1968, the program began as a bi-weekly television show hosted on CBS hosted by Mike Wallace and Harry Reasoner. The two sat on opposite sides of the cream-colored set, though the set's color was later changed to black, the color still used today. The show used a large stopwatch during transition periods and highlighted its topics through chroma key—both techniques are s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |