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Jean-Pierre Changeux
Jean-Pierre Changeux (; born 6 April 1936) is a French neuroscientist known for his research in several fields of biology, from the structure and function of proteins (with a focus on the allosteric proteins), to the early development of the nervous system up to cognitive functions. Although being famous in biological sciences for the MWC model, the identification and purification of the nicotinic acetylcholine receptor and the theory of epigenesis by synapse selection are also notable scientific achievements. Changeux is known by the non-scientific public for his ideas regarding the connection between mind and physical brain. As put forth in his book, ''Conversations on Mind, Matter and Mathematics'', Changeux strongly supports the view that the nervous system functions in a projective rather than reactive style and that interaction with the environment, rather than being instructive, results in the selection amongst a diversity of preexisting internal representations. Biography ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Domont
Domont () is a Communes of France, commune in the Val-d'Oise Departments of France, department and Île-de-France Regions of France, region of France. It is twinned with the Leicestershire village of Shepshed. Domont station has rail connections to Persan, Luzarches, Sarcelles and Paris. Population Twin towns — sister cities Domont is town twinning, twinned with: * Germering, Germany (1984) * Shepshed, United Kingdom (1989) * Gmina Wolsztyn, Wolsztyn, Poland (2005) * Buja, Italy (2009) Notable people from Domont *Bedi Buval footballer *Jean-Pierre Changeux neuroscientist *Yoann Djidonou footballer *Rémi Maréval footballer *Bertrand Ndzomo footballer *Eugene Jules Houdry Inventor See also *Communes of the Val-d'Oise department References External linksOfficial website *Association of Mayors of the Val d'Oise Communes of Val-d'Oise {{ValOise-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allostery
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site. The site to which the effector binds is termed the ''allosteric site'' or ''regulatory site''. Allosteric sites allow effectors to bind to the protein, often resulting in a conformational change and/or a change in protein dynamics. Effectors that enhance the protein's activity are referred to as ''allosteric activators'', whereas those that decrease the protein's activity are called ''allosteric inhibitors''. Allosteric regulations are a natural example of control loops, such as feedback from downstream products or feedforward from upstream substrates. Long-range allostery is especially important in cell signaling. Allosteric regulation is also particularly important in the cell's ability to adjust enzyme activity. The term ''allostery'' comes from the Ancient Greek ''allos'' (), "other", and ''stereos' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cognitive Functions
Cognitive skills, also called cognitive functions, cognitive abilities or cognitive capacities, are brain-based skills which are needed in acquisition of knowledge, manipulation of information and reasoning. They have more to do with the mechanisms of how people learn, remember, solve problems and pay attention, rather than with actual knowledge. Cognitive skills or functions encompass the domains of perception, attention, memory, learning, decision making, and language abilities. Specialisation of functions Cognitive science has provided theories of how the brain works, and these have been of great interest to researchers who work in the empirical fields of brain science. A fundamental question is whether cognitive functions, for example visual processing and language, are autonomous modules, or to what extent the functions depend on each other. Research evidence points towards a middle position, and it is now generally accepted that there is ''a degree'' of modularity in aspects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicotinic Receptors
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of many organisms. At the neuromuscular junction they are the primary receptor in muscle for motor nerve-muscle communication that controls muscle contraction. In the peripheral nervous system: (1) they transmit outgoing signals from the presynaptic to the postsynaptic cells within the sympathetic and parasympathetic nervous system, and (2) they are the receptors found on skeletal muscle that receive acetylcholine released to signal for muscular contraction. In the immune system, nAChRs regulate inflammatory processes and signal through distinct intracellular pathways. In insects, the cholinergic system is limited to the central nervous system. The nicotinic receptors are considered cholinergic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University College Of Physicians And Surgeons
Columbia University Vagelos College of Physicians and Surgeons (VP&S) is the graduate medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded in 1767 by Samuel Bard as the medical department of King's College (now Columbia University), VP&S was the first medical school in the Thirteen Colonies to award the Doctor of Medicine (MD) degree. Beginning in 1993, VP&S was also the first U.S. medical school to hold a white coat ceremony. According to '' U.S. News & World Report'', VP&S is one of the most selective medical schools in the United States based on average MCAT score, GPA, and acceptance rate. In 2018, 7,537 people applied and 1,007 were interviewed for 140 seats in its entering MD class. The median undergraduate GPA and average MCAT score for successful applicants in 2014 were 3.82 and 36, respectively. Columbia is third for research among American medical schools by ''U.S. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California Berkeley
The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant university and the founding campus of the University of California system. Its fourteen colleges and schools offer over 350 degree programs and enroll some 31,800 undergraduate and 13,200 graduate students. Berkeley ranks among the world's top universities. A founding member of the Association of American Universities, Berkeley hosts many leading research institutes dedicated to science, engineering, and mathematics. The university founded and maintains close relationships with three national laboratories at Berkeley, Livermore and Los Alamos, and has played a prominent role in many scientific advances, from the Manhattan Project and the discovery of 16 chemical elements to breakthroughs in computer science and genomics. Berkeley is also k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Copepod
Copepods (; meaning "oar-feet") are a group of small crustaceans found in nearly every freshwater and saltwater habitat (ecology), habitat. Some species are planktonic (inhabiting sea waters), some are benthos, benthic (living on the ocean floor), a number of species have parasitic phases, and some continental species may live in limnoterrestrial habitats and other wet terrestrial places, such as swamps, under leaf fall in wet forests, bogs, springs, ephemeral ponds, and puddles, damp moss, or water-filled recesses (phytotelmata) of plants such as bromeliads and pitcher plants. Many live underground in marine and freshwater caves, sinkholes, or stream beds. Copepods are sometimes used as Ecological indicator, biodiversity indicators. As with other crustaceans, copepods have a larval form. For copepods, the egg hatches into a Crustacean larvae#Nauplius, nauplius form, with a head and a tail but no true thorax or abdomen. The larva molts several times until it resembles the adult an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Banyuls-sur-Mer
Banyuls-sur-Mer (; ) is a commune in the Pyrénées-Orientales department in southern France. It was first settled by Greeks starting in 400 BCE. Geography Location Banyuls-sur-Mer is located in the canton of La Côte Vermeille and in the arrondissement of Céret. Banyuls-sur-Mer is neighbored by Cerbère, Port-Vendres, Argelès-sur-Mer and Collioure on its French borders, and by Espolla, Rabós, Colera and Portbou on its Spanish borders. The foothills of Pyrenees, the ''Monts Albères'', run into the Mediterranean Sea in Banyuls-sur-Mer, creating a steep cliff line. Toponymy Banyuls-sur-Mer was first mentioned in 981 as ''Balneum'' or ''Balneola''. In 1074, the town started being called ''Bannils de Maritimo'' in order to distinguish it from Banyuls-dels-Aspres, which lies away. In 1197, the town was mentioned as ''Banullis de Maredine'' and in 1674. In Catalan, it has been called ''Banyuls de la Marenda'' since the 19th century. The name Banyuls indicates the presence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agrégation
In France, the ''agrégation'' () is a competitive examination for civil service in the French public education system. Candidates for the examination, or ''agrégatifs'', become ''agrégés'' once they are admitted to the position of ''professeur agrégé''. In France, ''professeurs agrégés'' are distinguished from ''professeurs certifiés'' recruited through the CAPES training. The ''agrégés'' are usually expected to teach in sixth-form colleges (''lycées'') and universities, while the ''certifiés'' usually teach in secondary schools (''collèges''), although there is a significant overlap. The examination may require more than a year of preparation. The difficulty and selectivity (quota) vary from one discipline to another: there are about 300 such positions open each year for mathematics alone, but usually fewer positions are made available for humanities and social sciences (for example, 61 positions for philosophy were offered in 2018) and perhaps only one seat in som ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Master's Degree
A master's degree (from Latin ) is an academic degree awarded by universities or colleges upon completion of a course of study demonstrating mastery or a high-order overview of a specific field of study or area of professional practice. A master's degree normally requires previous study at the bachelor's degree, bachelor's level, either as a separate degree or as part of an integrated course. Within the area studied, master's graduates are expected to possess advanced knowledge of a specialized body of and applied topics; high order skills in |
Bachelor's Degree
A bachelor's degree (from Middle Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate academic degree awarded by colleges and universities upon completion of a course of study lasting three to six years (depending on institution and academic discipline). The two most common bachelor's degrees are the Bachelor of Arts (BA) and the Bachelor of Science (BS or BSc). In some institutions and educational systems, certain bachelor's degrees can only be taken as graduate or postgraduate educations after a first degree has been completed, although more commonly the successful completion of a bachelor's degree is a prerequisite for further courses such as a master's or a doctorate. In countries with qualifications frameworks, bachelor's degrees are normally one of the major levels in the framework (sometimes two levels where non-honours and honours bachelor's degrees are considered separately). However, some qualifications titled bachelor's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
