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Jan Hoeijmakers
Jan Hendrik Jozef Hoeijmakers (born 15 March in 1951 in Sevenum) is a Dutch molecular biologist, biochemist, and molecular geneticist. Education and career Hoeijmakers studied biology from 1969 at Radboud University Nijmegen with a master's degree in 1975 in molecular biology (with a focus on biochemistry and genetics). At the University of Amsterdam he completed course work from 1975 to 1979 for a doctorate in molecular medicine and then was a lecturer in the department of microbiology from 1979 to 1981. He received his doctorate in 1981 from the University of Amsterdam (with a complete publication list) under Piet Borst with dissertation '' Trypanosomes: Kinetoplast DNA and Antigenic Variation ''. At Erasmus University Rotterdam, as a member of Dirk Bootsma's group in the Institute of Genetics, Hoeijmakers was, in the department of cell biology and genetics, a senior scientist from 1981 to 1985, an associate professor from 1985 to 1993, and a professor of molecular genetics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription Factor II H
Transcription factor II Human (transcription factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TFIIH first came to light in 1989 when general transcription factor-δ or basic transcription factor 2 was characterized as an indispensable transcription factor in vitro. This factor was also isolated from yeast and finally named as TFIIH in 1992. TFIIH consists of ten subunits, 7 of which (ERCC2/XPD, ERCC3/XPB, GTF2H1/p62, GTF2H4/p52, GTF2H2/p44, GTF2H3/p34 and GTF2H5/TTDA) form the core complex. The cyclin activating kinase-subcomplex (CDK7, MAT1, and cyclin H) is linked to the core via the XPD protein. Two of the subunits, ERCC2/XPD and ERCC3/XPB, have helicase and ATPase activities and help create the transcription bubble. In a test tube these subunits are only required for transcription if the DNA template is not already denatured or if it is supercoiled. Two o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radboud University Nijmegen Alumni
{{disambig ...
Radbod, Radbot, Ratbod, Ratpot, Redbod, Redbad, Radboud, Rapoto, or sometimes just Boddo, is a Germanic masculine given name that may refer to: *Redbad, King of the Frisians (died 719) *Radbod (prefect) (833–54), Frankish prefect *Ratbod (archbishop of Trier) (died 915) *Radboud of Utrecht (died 917), bishop *Radbot, Count of Habsburg (died 1045) *Rabodo (died 1119) * ''Redbad'' (film), 2018 Dutch film Radboud may also refer to *Radboud University Nijmegen (formerly Catholic University Nijmegen), called after Saint Radboud *Radboud University Nijmegen Medical Centre The Radboud University Medical Center (Dutch: ''Radboudumc''), is the teaching hospital affiliated with the Radboud University Nijmegen, in the city of Nijmegen in the eastern-central part of the Netherlands ) , anthem = ( en, "William of N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Geneticists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Biochemists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Molecular Biologists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Blac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olav Thon Foundation
The Olav Thon Foundation ( no, Olav Thon Stiftelsen) is a Norwegian foundation and as such the biggest in Norway. Information In accordance with its statutes, the Olav Thon Foundation's primary activity is to own the Olav Thon Group, including the hotel chain Thon Hotels.Lotteri- og stiftelsestilsynet (i.e. Norwegian Gaming and Foundation Authority)Olav Thon opprettar Norges største stiftelse (i.e. Olav Thon Institutes Norway's Largest Foundation)10 December 2013. This makes the foundation a sizable business sector participant and one of the country's bigger real estate owners. The foundation's capital is approximately 25,4 billion crowns, of which 15 billions are so-called unattackable. Additionally, the Olav Thon Foundation gives annual economic support to scientific projects within mathematics, natural science, and medicine. This includes up to ten annual prizes of 500,000 crowns each, given to Norwegian or foreign scientists, and an annual international prize of five milli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bert Vogelstein
Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pioneer in the field of cancer genomics, his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in oncogenes and tumor suppressor genes. These studies now form the paradigm for modern cancer research and provided the basis for the notion of the somatic evolution of cancer. Research In the 1980s, Vogelstein developed new experimental approaches to study human tumors. His studies of various stages of colorectal cancers led him to propose a specific model for human tumorigenesis in 1988. In particular, he suggested that "cancer is caused by sequential mutations of specific oncogenes and tumor suppressor genes". The first tumor suppressor gene validating this hypothesis was that encoding p53. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Research Council
The European Research Council (ERC) is a public body for funding of scientific and technological research conducted within the European Union (EU). Established by the European Commission in 2007, the ERC is composed of an independent Scientific Council, its governing body consisting of distinguished researchers, and an Executive Agency, in charge of the implementation. It forms part of the framework programme of the union dedicated to research and innovation, Horizon 2020, preceded by the Seventh Research Framework Programme (FP7). The ERC budget is over €13 billion from 2014 – 2020 and comes from the Horizon 2020 programme, a part of the European Union's budget. Under Horizon 2020 it is estimated that around 7,000 ERC grantees will be funded and 42,000 team members supported, including 11,000 doctoral students and almost 16,000 post-doctoral researchers. Researchers from any field can compete for the grants that support pioneering projects. The ERC competitions are open ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Research Council
The Dutch Research Council (NWO, Dutch: Nederlandse Organisatie voor Wetenschappelijk Onderzoek) is the national research council of the Netherlands. NWO funds thousands of top researchers at universities and institutes and steers the course of Dutch science by means of subsidies and research programmes. NWO promotes quality and innovation in science. NWO is an independent administrative body under the auspices of the Dutch Ministry of Education, Culture and Science. NWO directs its approximate budget of 1 billion euros towards Dutch universities and institutes, often on a project basis. Also, NWO has its own research institutes and facilitates international cooperation. Current president of NWO since April 1st, 2021 is Marcel Levi. Former NWO presidents include Stan Gielen, Peter Nijkamp and Jos Engelen. NWO is also known for the annual Spinoza and Stevin Prizes. History The council was established in 1950 as ''Nederlandse Organisatie voor Zuiver-Wetenschappelijk Onderzoek' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinoza Prize
The Spinoza Prize ( nl, Spinozapremie) is an annual award of 2.5 million euro, to be spent on new research given by the Dutch Research Council (NWO). The award is the highest scientific award in the Netherlands. It is named after the philosopher Baruch de Spinoza Baruch (de) Spinoza (born Bento de Espinosa; later as an author and a correspondent ''Benedictus de Spinoza'', anglicized to ''Benedict de Spinoza''; 24 November 1632 – 21 February 1677) was a Dutch philosopher of Portuguese-Jewish origin, b .... The prize is awarded to researchers in the Netherlands who belong to the best in their field. Academics can nominate each other and an international commission evaluates the submissions. It is sometimes referred to as the Dutch Nobel Prize. List of winners The following persons have received the Spinoza Prize: References External links * {{Official website, http://www.nwo.nl/en/research-and-results/programmes/spinoza+prize, name = Spinoza Prize Awards establis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
