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J. Michael Bishop
John Michael Bishop (born February 22, 1936) is an American immunologist and microbiologist who shared the 1989 Nobel Prize in Physiology or Medicine with Harold E. Varmus and was co-winner of 1984 Alfred P. Sloan Prize. He serves as an active faculty member at the University of California, San Francisco (UCSF), where he also served as chancellor from 1998 to 2009.Autobiography on UCSF Website /ref>National Medal of Science details /ref> Education and earl ...
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York, Pennsylvania
York ( Pennsylvania Dutch: ''Yarrick''), known as the White Rose City (after the symbol of the House of York), is the county seat of York County, Pennsylvania, United States. It is located in the south-central region of the state. The population within York's city limits was 43,718 at the 2010 census, a 7.0% increase from the 2000 census count of 40,862. When combined with the adjacent boroughs of West York and North York and surrounding Spring Garden, West Manchester, and Springettsbury townships, the population of Greater York was 108,386. York is the 11th largest city in Pennsylvania. History 18th century York, also known as Yorktown in the mid 18th to early 19th centuries, was founded in 1741 by settlers from the Philadelphia region and named for the English city of the same name. By 1777, most of the area residents were of either German or Scots-Irish descent. York was incorporated as a borough on September 24, 1787, and as a city on January 11, 1887. York served ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harold E
Harold may refer to: People * Harold (given name), including a list of persons and fictional characters with the name * Harold (surname), surname in the English language * András Arató, known in meme culture as "Hide the Pain Harold" Arts and entertainment * ''Harold'' (film), a 2008 comedy film * ''Harold'', an 1876 poem by Alfred, Lord Tennyson * ''Harold, the Last of the Saxons'', an 1848 book by Edward Bulwer-Lytton, 1st Baron Lytton * ''Harold or the Norman Conquest'', an opera by Frederic Cowen * ''Harold'', an 1885 opera by Eduard Nápravník * Harold, a character from the cartoon ''The Grim Adventures of Billy & Mandy'' *Harold & Kumar, a US movie; Harold/Harry is the main actor in the show. Places ;In the United States * Alpine, Los Angeles County, California, an erstwhile settlement that was also known as Harold * Harold, Florida, an unincorporated community * Harold, Kentucky, an unincorporated community * Harold, Missouri, an unincorporated community ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Src (gene)
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma), is a non-receptor tyrosine kinase protein that in humans is encoded by the ''SRC'' gene. It belongs to a family of Src family kinases and is similar to the v-Src (viral Src) gene of Rous sarcoma virus. It includes an SH2 domain, an SH3 domain and a tyrosine kinase domain. Two transcript variants encoding the same protein have been found for this gene. c-Src phosphorylates specific tyrosine residues in other tyrosine kinases. It plays a role in the regulation of embryonic development and cell growth. An elevated level of activity of c-Src is suggested to be linked to cancer progression by promoting other signals. Mutations in c-Src could be involved in the malignant progression of colon cancer. c-Src should not be confused with CSK (C-terminal Src kinase), an enzyme that phosphorylates c-Src at its C-terminus and provides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncogenes
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.Kimball's Biology Pages. "Oncogenes" Free full text Most normal cells will undergo a programmed form of rapid cell death () when critical functions are altered and malfunctioning. Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes: normal genes involved in cell growth and proliferation or inhibition of apoptosis. If, through mutation, normal genes promoting cellular growth are up-regulated (gain-of-function mutation), they will predisp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retrovirus
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. Once inside the host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus ''retro'' (backwards). The new DNA is then incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along with the cell's own genes, producing the proteins required to assemble new copies of the virus. Although retroviruses have different subfamilies, they have three basic groups: the oncoretroviruses (oncogenic retroviruses), the lentiviruses (slow retroviruses) and the spumaviruses (foamy viruses). The oncoretroviruses are able to cause cancer in some species, the lentiviru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peyton Rous
Francis Peyton Rous () (October 5, 1879 – February 16, 1970) was an American pathologist at the Rockefeller University known for his works in oncoviruses, blood transfusion and physiology of digestion. A medical graduate from the Johns Hopkins University, he was discouraged to become a practicing physician due to severe tuberculosis. After three years of working as an instructor of pathology at the University of Michigan, he became dedicated researcher at the Rockefeller Institute for Medical Research for the rest of his career. His discovery in 1911 that a chicken tumor was caused by a virus (later named Rous sarcoma virus) led to more discoveries and understanding of the role of viruses in the development of certain types of cancer. He was awarded a Nobel Prize in Physiology or Medicine for his work in 1966, 55 years after his initial discovery and he remains the oldest recipient of the Nobel Prize in Medicine or Physiology. He and Joseph R. Turner studied methods to make ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hamburg
(male), (female) en, Hamburger(s), Hamburgian(s) , timezone1 = Central (CET) , utc_offset1 = +1 , timezone1_DST = Central (CEST) , utc_offset1_DST = +2 , postal_code_type = Postal code(s) , postal_code = 20001–21149, 22001–22769 , area_code_type = Area code(s) , area_code = 040 , registration_plate = , blank_name_sec1 = GRP (nominal) , blank_info_sec1 = €123 billion (2019) , blank1_name_sec1 = GRP per capita , blank1_info_sec1 = €67,000 (2019) , blank1_name_sec2 = HDI (2018) , blank1_info_sec2 = 0.976 · 1st of 16 , iso_code = DE-HH , blank_name_sec2 = NUTS Region , blank_info_sec2 = DE6 , website = , footnotes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lambda Chi Alpha
Lambda Chi Alpha (), commonly known as Lambda Chi, is a college fraternity in North America which was founded at Boston University in 1909. It is one of the largest social fraternities in North America, with more than 300,000 lifetime members and active chapters and colonies at 195 universities. The youngest of the fifteen largest social fraternities, Lambda Chi Alpha has initiated the third highest number of men ever, based on NIC statistics. Lambda Chi's International Headquarters is located in Indianapolis, Indiana. Its members are referred to as "Lambda Chis", "LXAs", "LCAs", "Lambdas", “Chops”, and "Choppers". It was a member of the North American Interfraternity Conference (NIC) until October 2015. History Founding Lambda Chi Alpha was founded by Warren A. Cole, a law student at Boston University. There are two different accounts of this founding. The official story adopted by Warren A. Cole and Albert Cross is that on , Cole, Percival C. Morse, and Clyde K. Nichols ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gettysburg College
Gettysburg College is a private liberal arts college in Gettysburg, Pennsylvania. Founded in 1832, the campus is adjacent to the Gettysburg Battlefield. Gettysburg College has about 2,600 students, with roughly equal numbers of men and women. Gettysburg students come from 41 states, Washington, D.C., and 39 countries. The school hosts 24 NCAA Division III men's and women's teams, known as the Bullets, and many club, intramural, and recreational programs. The college is also the home of ''The Gettysburg Review'', a literary magazine. History Founding and early roots Gettysburg College was founded in 1832, as a sister institution for the Lutheran Theological Seminary. Both owe their inception to Thaddeus Stevens, a Radical Republican and abolitionist from Gettysburg. The college's original name was Pennsylvania College; it was founded by Samuel Simon Schmucker. In 1839, seven years after Gettysburg College was first founded, Drs. George McClellan (founder of Jefferson Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
