|
International Protein Index
The International Protein Index (IPI) is a defunct protein database launched in 2001 by the European Bioinformatics Institute (EBI), and closed in 2011. Its purpose was to provide the proteomics community with a resource that enables * accession numbers from a variety of bioinformatics databases to be mapped * a complete set of proteins for a species i.e. a reference set In its last version, the IPI contained the complete reference sets for six animal species: ''Homo sapiens'' (human), ''Mus musculus'' (mouse), ''Rattus norvegicus'' (rat), ''Bos taurus'' (cattle), ''Gallus gallus'' (chicken) and ''Danio rerio'' (zebrafish); and one plant species: ''Arabidopsis thaliana'' (thale cress). The human, mouse and rat datasets were the first to be developed, combining information taken from the Swiss-Prot, TrEMBL, Ensembl and RefSeq databases. History In 2001, when the IPI was launched, databases cataloguing human genes varied greatly and had few links between them. Since then, much more d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TrEMBL
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature. It is maintained by the UniProt consortium, which consists of several European bioinformatics organisations and a foundation from Washington, DC, United States. The UniProt consortium The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services. SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases. PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Data Synchronization
Data synchronization is the process of establishing consistency between source and target data stores, and the continuous harmonization of the data over time. It is fundamental to a wide variety of applications, including file synchronization and mobile device synchronization. Data synchronization can also be useful in encryption for synchronizing public key servers. File-based solutions There are tools available for file synchronization, version control ( CVS, Subversion, etc.), distributed filesystems (Coda, etc.), and mirroring (rsync, etc.), in that all these attempt to keep sets of files synchronized. However, only version control and file synchronization tools can deal with modifications to more than one copy of the files. * File synchronization is commonly used for home backups on external hard drives or updating for transport on USB flash drives. The automatic process prevents copying already identical files, thus can save considerable time relative to a manual copy, al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Index (publishing)
An index (plural: usually indexes, more rarely indices; see below) is a list of words or phrases ('headings') and associated pointers ('locators') to where useful material relating to that heading can be found in a document or collection of documents. Examples are an index in the back matter of a book and an index that serves as a library catalog. An index differs from a word index, or ''concordance'', in focusing on the subject of the text rather than the exact words in a text, and it differs from a table of contents because the index is ordered by subject, regardless of whether it is early or late in the book, while the listed items in a table of contents is placed in the same order as the book. In a traditional ''back-of-the-book index'', the headings will include names of people, places, events, and concepts selected as being relevant and of interest to a possible reader of the book. The indexer performing the selection may be the author, the editor, or a professional inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indexes
Index (or its plural form indices) may refer to: Arts, entertainment, and media Fictional entities * Index (''A Certain Magical Index''), a character in the light novel series ''A Certain Magical Index'' * The Index, an item on a Halo megastructure in the ''Halo'' series of video games Periodicals and news portals * ''Index Magazine'', a publication for art and culture * Index.hr, a Croatian online newspaper * index.hu, a Hungarian-language news and community portal * ''The Index'' (Kalamazoo College), a student newspaper * ''The Index'', an 1860s European propaganda journal created by Henry Hotze to support the Confederate States of America * ''Truman State University Index'', a student newspaper Other arts, entertainment and media * The Index (band) * ''Indexed'', a Web cartoon by Jessica Hagy * ''Index'', album by Ana Mena Business enterprises and events * Index (retailer), a former UK catalogue retailer * INDEX, a market research fair in Lucknow, India * Index Corporat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Databases In The United Kingdom
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an application ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UniProt
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature. It is maintained by the UniProt consortium, which consists of several European bioinformatics organisations and a foundation from Washington, DC, United States. The UniProt consortium The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services. SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases. PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Geor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteomics (journal)
''Proteomics'' is a peer-reviewed scientific journal covering topics including whole proteome analysis of organisms, protein expression profiling, disease, pharmaceutical, agricultural and biotechnological applications, and analysis of cellular systems, organelles and protein complexes. It is published by Wiley VCH and the current editor-in-chief is Lucie Kalvodova. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.984, ranking it 23rd out of 78 journals in the category "Biochemical Research Methods". References Publications established in 2006 English-language journals Bimonthly journals Proteomics journals Wiley (publisher) academic journals {{biochem-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RefSeq
The Reference Sequence (RefSeq) database is an open access, annotated and curated collection of publicly available nucleotide sequences ( DNA, RNA) and their protein products. RefSeq was first introduced in 2000. This database is built by National Center for Biotechnology Information (NCBI), and, unlike GenBank, provides only a single record for each natural biological molecule (i.e. DNA, RNA or protein) for major organisms ranging from viruses to bacteria to eukaryotes. For each model organism, ''RefSeq'' aims to provide separate and linked records for the genomic DNA, the gene transcripts, and the proteins arising from those transcripts. ''RefSeq'' is limited to major organisms for which sufficient data are available (121,461 distinct "named" organisms as of July 2022), while GenBank includes sequences for any organism submitted (approximately 504,000 formally described species). RefSeq categories RefSeq collection comprises different data types, with different origins, so it i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ensembl
Ensembl genome database project is a scientific project at the European Bioinformatics Institute, which provides a centralized resource for geneticists, molecular biologists and other researchers studying the genomes of our own species and other vertebrates and model organisms. Ensembl is one of several well known genome browsers for the retrieval of genomic information. Similar databases and browsers are found at NCBI and the University of California, Santa Cruz (UCSC). History The human genome consists of three billion base pairs, which code for approximately 20,000–25,000 genes. However the genome alone is of little use, unless the locations and relationships of individual genes can be identified. One option is manual annotation, whereby a team of scientists tries to locate genes using experimental data from scientific journals and public databases. However this is a slow, painstaking task. The alternative, known as automated annotation, is to use the power of computers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Proteomics")
