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Intermediate Trophoblast
Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast. It is sub-categorized by location: *Villous intermediate trophoblast: **at anchoring villi of trophoblastic column *Implantation site intermediate trophoblast: **at implantation site (or basal plate), differentiated from villous intermediate trophoblast *Chorionic-type intermediate trophoblast **at chorionic laeve of fetal membrane, differentiated from villous intermediate trophoblast Function The function of the implantation site intermediate trophoblast is to anchor the placenta to the maternal tissue. Histomorphology * Villous intermediate trophoblast ** polyhedral and uniform nuclei ** prominent cell border; abundant eosinophilic to clear cytoplasm ** cohesive growth * Implantation site intermediate trophoblast ** pleomorphic irregular nuclei, large and hyperchromatic, may multinucleation ** abundant eosinophilic to amphophilic cytoplasm ** infiltrative growth (split ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intermediate Trophoblast - High Mag
Intermediate may refer to: * Intermediate 1 or Intermediate 2, educational qualifications in Scotland * Intermediate (anatomy), the relative location of an anatomical structure lying between two other structures: see Anatomical terms of location * Intermediate Edison Screw, a system of light bulb connectors * Intermediate goods, goods used to produce other goods * Middle school, also known as ''intermediate school'' * Intermediate Examination, standardized post-secondary exams in the Indian Subcontinent, also known as the Higher Secondary Examination * In chemistry, a reaction intermediate is a reaction product that serves as a precursor for other reactions * A reactive intermediate is a highly reactive reaction intermediate, hence usually short-lived * Intermediate car, an automobile size classification * Intermediate cartridge, a type of firearms cartridge * Intermediate composition, a geological classification of the mineral composition of a rock, between mafic and fels ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intermediate Trophoblast - Lmwk - High Mag
Intermediate may refer to: * Intermediate 1 or Intermediate 2, educational qualifications in Scotland * Intermediate (anatomy), the relative location of an anatomical structure lying between two other structures: see Anatomical terms of location * Intermediate Edison Screw, a system of light bulb connectors * Intermediate goods, goods used to produce other goods * Middle school, also known as ''intermediate school'' * Intermediate Examination, standardized post-secondary exams in the Indian Subcontinent, also known as the Higher Secondary Examination * In chemistry, a reaction intermediate is a reaction product that serves as a precursor for other reactions * A reactive intermediate is a highly reactive reaction intermediate, hence usually short-lived * Intermediate car, an automobile size classification * Intermediate cartridge, a type of firearms cartridge * Intermediate composition, a geological classification of the mineral composition of a rock, between mafic and fels ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trophoblast
The trophoblast (from Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures that do not directly contribute to the embryo. After gastrulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiation, the cells in the human embryo lose their totipotency and are no longer totipotent stem cells because they cannot form a trophoblast. They are now pluripotent stem cells. Structure The trophoblast proliferates and differentiates into two cell layers at approximately six days after fertilization for humans. Function Trophoblasts are specialized cells of the placenta that play a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytotrophoblast
"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo. The cytotrophoblast is considered to be the trophoblastic stem cell because the layer surrounding the blastocyst remains while daughter cells differentiate and proliferate to function in multiple roles. There are two lineages that cytotrophoblastic cells may differentiate through: fusion and invasive. The fusion lineage yields syncytiotrophoblast and the invasive lineage yields interstitial cytotrophoblast cells. Cytotrophoblastic cells play an important role in the implantation of an embryo in the uterus. Fusion lineage The formation of all syncytiotrophoblast is from the fusion of two or more cytotrophoblasts via this fusion pathway. This pathway is important because the syncytiotrophoblast plays an important role in fetal-maternal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placenta
The placenta is a temporary embryonic and later fetal organ (anatomy), organ that begins embryonic development, developing from the blastocyst shortly after implantation (embryology), implantation. It plays critical roles in facilitating nutrient, gas and waste exchange between the physically separate maternal and fetal circulations, and is an important Endocrine system, endocrine organ, producing hormones that regulate both Maternal physiological changes in pregnancy, maternal and fetal physiology during pregnancy. The placenta connects to the fetus via the umbilical cord, and on the opposite aspect to the maternal uterus in a species-dependent manner. In humans, a thin layer of maternal decidual (Endometrium, endometrial) tissue comes away with the placenta when it is expelled from the uterus following birth (sometimes incorrectly referred to as the 'maternal part' of the placenta). Placentas are a defining characteristic of placental mammals, but are also found in marsupials an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exaggerated Placental Site
Exaggeration is the representation of something as more extreme or dramatic than it really is. Exaggeration may occur intentionally or unintentionally. Exaggeration can be a rhetorical device or figure of speech. It may be used to evoke strong feelings or to create a strong impression. Amplifying achievements, obstacles and problems to seek attention is an everyday occurrence Inflating the difficulty of achieving a goal after attaining it, can be used to bolster self-esteem. In the arts, exaggerations are used to create emphasis or effect. As a literary device, exaggerations is often used in poetry, and is frequently encountered in casual speech. Many times the usages of hyperbole describes something as better or worse than it really is. An example of hyperbole is: "The bag weighed a ton." Hyperbole makes the point that the bag was very heavy, though it probably does not weigh a ton. Exaggerating is also a type of deception,Guerrero, L., Anderson, P., Afifi, W. (2007). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placental Site Nodule
A placental site nodule (PSN) is benign remnant from a previous pregnancy. Presentation They are typically asymptomatic and found incidentally. Pathology PSNs are intermediate trophoblastic remnants. Diagnosis PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage. Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes ( cervical) squamous cell carcinoma Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on th ..., gestational trophoblastic disease, and exaggerated placental site. Prognosis PSN are benign. Once removed, they do not require any treatment and do not rec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placental Site Trophoblastic Tumour
Placental site trophoblastic tumor is a form of gestational trophoblastic disease, which is thought to arise from intermediate trophoblast. The tumor may secrete human placental lactogen, and result in a false-positive pregnancy test. A placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy (5%). Compared to choriocarcinoma or invasive mole, hemorrhage is less conspicuous and serum β-HCG level is low, making early diagnosis difficult. Immunohistochemistry: Often stains with hPL, keratin, Mel-CAM, EGFR. Treatment Because chemotherapy is ineffective; the patient should undergo hysterectomy Hysterectomy is the surgical removal of the uterus. It may also involve removal of the cervix, ovaries (oophorectomy), Fallopian tubes (salpingectomy), and other surrounding st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epithelioid Trophoblastic Tumour
Epithelioid trophoblastic tumor (ETT) is a gestational trophoblastic disease with about 110 case reports in the literature. It is a trophoblastic tumor of neoplastic chorionic type associated with the intermediate trophoblast. Signs and symptoms * Vaginal bleeding: The most common presenting symptom is vaginal bleeding, which is associated with mild elevation of serum β hCG ( 6/10HPF is an unfavorable prognostic factor. Epithelioid trophoblastic tumo ''Pathology outlines'', August 26, 2017. References {{reflist Germ cell neoplasia Rare diseases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
