Inocybe Aeruginascens
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Inocybe Aeruginascens
''Inocybe aeruginascens'' is a member of the genus ''Inocybe'' which is widely distributed in Europe. The species was first documented by I. Ferencz in Ócsa, Hungary on June 15, 1965. Description ''Inocybe aeruginascens'' is a small mycorrhizal mushroom with a conic to convex cap which becomes plane in age and is often fibrillose near the margin. It is usually less than 5 cm across, has a slightly darker blunt umbo and an incurved margin when young. The cap color varies from buff to light yellow brown, usually with greenish stains which disappear when the mushroom dries. The gills are adnate to nearly free, numerous, colored pale brown, grayish brown, or tobacco brown. The fruit body has greenish tones and bruises blue where damaged. The spores are smooth and ellipsoid, measuring 6–9.5 x 4.5 micrometres and forming a clay brown spore print. The stem is 2–7 cm long, 3 to 8 mm thick, and is equal width for the whole length, sometimes with some swelling at ...
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Margit Babos
Margit Babos (maiden name Margit Greskovits, 1931–2009) was a Hungarian mycologist born on 28 October 1931 in Budapest. She became one of the most widely recognized mycologists in the second half of the 20th century in Eastern Europe, with contributions to mycological research, fungal taxonomy and recording the mycoflora of Hungary. Bibliographical data Babos joined the plant herbarium of the Hungarian Natural History Museum in 1951, first as a curator in the paleobotany department, then in the phycology department. In 1954, she joined the Mycology Department under the supervision of Dr. Gábor Bohus. They adopted the modified Herpell exsiccation method which resulted in well-preserved dried specimens of fungi. Although this was a tedious method and often required the process to be started in the field, Babos prepared more than 20,000 Herpell-exsiccata, which forms a valuable part of the fungus collection of the Hungarian National History Museum. Shortly after joining the M ...
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Psilocin
Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance. It is present in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin. Psilocin is a Schedule I drug under the Convention on Psychotropic Substances. Acting on the 5-HT2A receptors, psilocin modulates the production and reuptake of serotonin. The mind-altering effects of psilocin are highly variable and subjective and resemble those of LSD and DMT. Chemistry Psilocin and its phosphorylated cousin, psilocybin, were first isolated and named in 1958 by Swiss chemist Albert Hofmann. Hofmann obtained the chemicals from laboratory-grown specimens of the entheogenic mushroom ''Psilocybe mexicana''. Hofmann also succeeded in finding synthetic routes to these chemicals. Psilocin can be obtained by dephosphorylation of natural psilocybin under strongly acidic or under alkaline conditions (hyd ...
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Psychedelic Tryptamine Carriers
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence'' Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term ''psychedelics'' is used more broadly to include all hallucinogens; this article uses the narrower definition of ''psychedelics''. Psychedelics cause specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness.Leary, Timothy; Metzner, Ralph (1964). ''The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead'' Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of mind. The "classical" psychedelics, the psyc ...
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Psychoactive Fungi
This is a list of psychoactive plants, fungi, and animals. Plants Psychoactive plants include, but are not limited to, the following examples: * ''Cannabis'': cannabinoids * Tobacco: nicotine and beta-carboline alkaloids * Coca: cocaine * Opium Poppy: morphine, codeine, thebaine, papaverine, noscapine, and narceine * '' Salvia divinorum'': salvinorin A * Khat: cathine and cathinone * Kava: kavalactones * Nutmeg: myristicin * Nightshade (''Solanaceae'') plants containing hyoscyamine, atropine, and scopolamine: ** ''Datura'' ** Deadly nightshade (''Atropa belladonna'') ** Henbane (''Hyoscyamus niger'') ** Mandrake (''Mandragora officinarum'') ** Other ''Solanaceae'' * Psychoactive cacti, which contain mainly mescaline: ** Peyote ** Other ''Lophophora'' ** Peruvian Torch cactus ** San Pedro cactus ** Other ''Echinopsis'' * Minimally psychoactive plants that contain mainly caffeine and theobromine: ** Coffee ** Tea (also contains theanine) ** Guarana ** Yerba Mate ** Coc ...
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List Of Psilocybin Mushrooms
Psilocybin mushrooms are mushrooms which contain the hallucinogenic substances psilocybin, psilocin, baeocystin and norbaeocystin. The mushrooms are collected and grown as an entheogen and recreational drug, despite being illegal in many countries. Many psilocybin mushrooms are in the genus '' Psilocybe'', but species across several other genera contain the drugs. General * ''Conocybe'' * ''Galerina'' * ''Gymnopilus'' * ''Inocybe'' * ''Panaeolus'' * ''Pholiotina'' * ''Pluteus'' * ''Psilocybe'' ''Conocybe'' *'' Conocybe siligineoides'' R. Heim *''Conocybe velutipes'' ( Velen.) Hauskn. & Svrcek ''Galerina'' *'' Galerina steglichii'' Besl ''Gymnopilus'' *''Gymnopilus aeruginosus'' (Peck) Singer (photo) *'' Gymnopilus braendlei'' (Peck) Hesler *''Gymnopilus cyanopalmicola'' Guzm.-Dáv *''Gymnopilus dilepis'' (Berk. & Broome) Singer *''Gymnopilus dunensis'' H. Bashir, Jabeen & Khalid *''Gymnopilus intermedius'' (Singer) Singer *''Gymnopilus lateritius'' (Pat.) Murrill *''Gymn ...
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List Of Inocybe Species
''Inocybe'' is a large genus of mushroom-producing fungi in the order Agaricales. The genus is widely distributed in the Northern Hemisphere. , Index Fungorum accepts 848 species in ''Inocybe''. As of 2023, it is estimated that there are 1050 species in this genus. A B C D E F G H I J K L M N O P Q R S T U V U W X Y Z __NOTOC__ A *''Inocybe aberrans'' (E.Horak) Garrido 1988 *'' Inocybe abietis'' Kühner 1953 *'' Inocybe abnormispora'' Alessio 1987 *'' Inocybe abundans'' Murrill 1911 *'' Inocybe acriolen'' Grund & D.E.Stuntz 1975 *'' Inocybe acuta'' Boud. 1917 *'' Inocybe acutata'' Tak. Kobay. & Nagas. 1993 *'' Inocybe acutoides'' Kokkonen & Vauras 2013 *''Inocybe acystidiosa'' Kauffman 1924 *'' Inocybe adaequata'' (Britzelm.) Sacc. 1887 – Europe *'' Inocybe aeruginascens'' Babos 1970 (psychoactive) *'' Inocybe aestiva'' Kropp, Matheny & Hutchison 2013 – USA *'' Inocybe agardhii'' (N.Lund) P.D.Orton 1960 – United Kingdom *'' Inocybe agglutinat ...
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Pholiotina Cyanopus
''Pholiotina cyanopus'' is a species of fungus that contains psychoactive compounds including psilocybin and the uncommon aeruginascin. Originally described as ''Galerula cyanopus'' by American mycologist George Francis Atkinson in 1918. It was transferred to ''Conocybe'' by Robert Kühner in 1935 before being transferred to ''Pholiotina'' by Rolf Singer in 1950. A 2013 molecular phylogenetics study found it to belong to a group of species currently assigned to ''Pholiotina'' that are more closely related to ''Galerella nigeriensis'' than to ''Pholiotina'' or ''Conocybe''. It is likely that it will be moved to a different genus in the future, but this has not happened yet. It is very similar to '' Pholiotina smithii'', a species known only from North America, from which it differs slightly in the color of its cap and gills and the width of its cheilocystidia. Some authors have speculated that the ''P. smithii'' could be a junior synonym of ''P. cyanopus'', but this has not been c ...
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Analog (chemistry)
A structural analog (analogue in modern traditional English; Commonwealth English), also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced with other atoms, groups, or substructures. A structural analog can be imagined to be formed, at least theoretically, from the other compound. Structural analogs are often isoelectronic. Despite a high chemical similarity, structural analogs are not necessarily functional analogs and can have very different physical, chemical, biochemical, or pharmacological properties. In drug discovery, either a large series of structural analogs of an initial lead compound are created and tested as part of a structure–activity relationship study or a database is screened for structural analogs of a lead compound. Chemical analogues of il ...
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Aeruginascin
Aeruginascin or ''N,N,N''-trimethyl-4-phosphoryloxytryptamine is an indoleamine derivative which occurs naturally within the mushroom ''Inocybe aeruginascens'' and ''Pholiotina cyanopus''. Aeruginascin is the ''N''-trimethyl analogue of psilocybin. It is closely related to the frog skin toxin bufotenidine (5-HTQ), a potent 5-HT3 receptor agonist, but the aeruginascin metabolite 4-HO-TMT shows strong binding at the 5-HT2 receptors similar to psilocin Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance. It is present in most psychedelic mushrooms together with its phosphorylated counte .... The first scientific literature about the pharmacological effects of aeruginascin is from a study published by Gartz in 1989. Across 23 analyzed cases of accidental hallucinogenic mushroom poisonings, people who had ingested the mushroom ''Inocybe aeruginascens'' reported only euphor ...
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Tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan. The chemical structure is defined by an indole ─ a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the first one being the heterocyclic nitrogen). The structure of tryptamine is a shared feature of certain aminergic neuromodulators including melatonin, serotonin, bufotenin and psychedelic derivatives such as dimethyltryptamine (DMT), psilocybin, psilocin and others. Tryptamine has been shown to activate trace amine-associated receptors expressed in the mammalian brain, and regulates the activity of dopaminergic, serotonergic and glutamatergic systems. In the human gut, symbiotic bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility. Multiple tryptamine-derived drugs have been developed to treat migraines, while trace amine-associated receptors are being explored as a ...
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Methyl
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula . In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bounded to the rest of the molecule by a single covalent bond (), it can be found on its own in any of three forms: methanide anion (), methylium cation () or methyl radical (). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed. Methyl cation, anion, and radical Methyl cation The methylium cation () exists in the gas phase, but is otherwise not encountered. Some compounds are considered to be sources of the cation, and this simplification is used pervasively in organic chemistry. For example, protonation of methanol gives an elect ...
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Indoleamine
Indolamines are a family of neurotransmitters that share a common molecular structure (namely, indolamine). Indolamines are a classification of monoamine neurotransmitter, along with catecholamines and ethylamine derivatives. A common example of an indolamine is the tryptophan derivative serotonin, a neurotransmitter involved in mood and sleep. Another example of an indolamine is melatonin. In biochemistry, indolamines are substituted indole compounds that contain an amino group. Examples of indolamines include the lysergamides. Synthesis Indolamines are biologically synthesized from the essential amino acid tryptophan. Tryptophan is synthesized into serotonin through the addition of a hydroxyl group by the enzyme ''tryptophan hydroxylase'' and the subsequent removal of the carboxyl group by the enzyme ''5-HTP decarboxylase''.Carlson, Neil R. ''Physiology of Behavior''. 11th ed. Vol. 1. N.p.: Pearson Education, n.d. Print. See also *Indole *Tryptamine Tryptamine ...
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