IgG4-related Ophthalmic Disease
   HOME
*



picture info

IgG4-related Ophthalmic Disease
IgG4-related ophthalmic disease (IgG4-ROD) is the recommended term to describe orbital (eye socket) manifestations of the systemic condition IgG4-related disease, which is characterised by infiltration of lymphocytes and plasma cells and subsequent fibrosis in involved structures. It can involve one or more of the orbital structures. Frequently involved structures include the lacrimal glands, extraocular muscles, infraorbital nerve, supraorbital nerve and eyelids. It has also been speculated that ligneous conjunctivitis may be a manifestation of IgG4-related disease (IgG4-RD). As is the case with other manifestations of IgG4-related disease, a prompt response to steroid therapy is a characteristic feature of IgG4-ROD in most cases, unless significant fibrosis has already occurred. It basically can cause loss of vision and in other cases, cause skin irritation and loss of brain function Symptoms Symptoms, if any, can be mild even in the presence of sig ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and oth ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Exophthalmos
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and extraocular muscles, which can be visualized by CT or MRI. If left untreated, exophthalmos can cause the eyelids to fail to close during sleep, leading to corneal dryness and damage. Another possible complication is a form of redness or irritation called superior limbic keratoconjunctivitis, in which the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the displacement of the eye may also compre ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Eye (journal)
''Eye'' is a monthly peer-reviewed medical journal covering ophthalmology. It was established in 1881 as the ''Transactions of the Ophthalmological Societies of the United Kingdom'', obtaining its current name in 1987. It is published by Springer Nature and is the official journal of the Royal College of Ophthalmologists. The editor-in-chief is Sobha Sivaprasad (Moorfields Eye Hospital). According to the ''Journal Citation Reports'', ''Eye'' has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 4.456. References External links * Ophthalmology journals Nature Research academic journals Bimonthly journals Publications established in 1881 English-language journals 1881 establishments in the United Kingdom Academic journals associated with learned an ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


JAMA Ophthalmology
''JAMA Ophthalmology'' (formerly ''Archives of Ophthalmology'') is a monthly peer-reviewed medical journal covering all aspects of ophthalmology. The editor-in-chief is Neil M. Bressler (Johns Hopkins School of Medicine). It is published by the American Medical Association, with which it has been affiliated since 1929. History The journal was established in New York in 1869 as the ''Archives of Ophthalmology and Otology'', with a simultaneous German language version published in Karlsruhe, Germany, as ''Archiv für Augen- und Ohrenheilkunde''; sometimes articles would be slightly different. The editors were Hermann Knapp (New York), who practiced both ophthalmology and otology, with greater emphasis on the eye, and the otologist Salomon Moos (Heidelberg). The journal obtained its current name in 2013. Naming History Abstracting and indexing The journal is abstracted and indexed in: According to ''Journal Citation Reports'', the journal has a 2021 impact factor of 8.253, r ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Arthritis & Rheumatology
''Arthritis & Rheumatology'' is a monthly peer-reviewed medical journal covering the natural history, pathophysiology, treatment, and outcome of the rheumatic diseases. It is an official journal of the American College of Rheumatology. It was established in 1958 as ''Arthritis & Rheumatism'' and obtained its current name in 2014. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 10.995. References External links * American College of Rheumatology Publications established in 1958 Wiley (publisher) academic journals Monthly journals English-language journals Rheumatology journals {{med-journal-stub ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Idiopathic Orbital Inflammatory Disease
Idiopathic orbital inflammatory (IOI) disease refers to a marginated mass-like enhancing soft tissue involving any area of the orbit. It is the most common painful orbital mass in the adult population, and is associated with proptosis, cranial nerve palsy (Tolosa–Hunt syndrome), uveitis, and retinal detachment. Idiopathic orbital inflammatory syndrome, also known as orbital pseudotumor, was first described by GleasonGleason JE. Idipathic myositis involving the extraocular muscles. Ophthalmol Rec.12:471–478, 1903 in 1903 and by Busse and Hochheim.Busse O, Hochheim W. cited by Dunnington JH, Berke RN. Exophthalmos due to chronic orbital myositic. Arch Ophthal . 30:446–466, 1943 It was then characterized as a distinct entity in 1905 by Birch-Hirschfeld.Birch-Hirschfeld A. Zur diagnostic and pathologic der orbital tumoren. Ber Dtsch Ophthalmol Ges. 32: 127–135, 1905Birch-Hirschfeld A. Handbuch der gesamten augenheilkunde, vol. 9. Berlin: Julius Springer. p. 251–253, 1930 It ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Idiopathic Orbital Inflammatory Disease
Idiopathic orbital inflammatory (IOI) disease refers to a marginated mass-like enhancing soft tissue involving any area of the orbit. It is the most common painful orbital mass in the adult population, and is associated with proptosis, cranial nerve palsy (Tolosa–Hunt syndrome), uveitis, and retinal detachment. Idiopathic orbital inflammatory syndrome, also known as orbital pseudotumor, was first described by GleasonGleason JE. Idipathic myositis involving the extraocular muscles. Ophthalmol Rec.12:471–478, 1903 in 1903 and by Busse and Hochheim.Busse O, Hochheim W. cited by Dunnington JH, Berke RN. Exophthalmos due to chronic orbital myositic. Arch Ophthal . 30:446–466, 1943 It was then characterized as a distinct entity in 1905 by Birch-Hirschfeld.Birch-Hirschfeld A. Zur diagnostic and pathologic der orbital tumoren. Ber Dtsch Ophthalmol Ges. 32: 127–135, 1905Birch-Hirschfeld A. Handbuch der gesamten augenheilkunde, vol. 9. Berlin: Julius Springer. p. 251–253, 1930 It ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Optic nerve
In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual information from the retina to the brain. In humans, the optic nerve is derived from optic stalks during the seventh week of development and is composed of retinal ganglion cell axons and glial cells; it extends from the optic disc to the optic chiasma and continues as the optic tract to the lateral geniculate nucleus, pretectal nuclei, and superior colliculus. Structure The optic nerve has been classified as the second of twelve paired cranial nerves, but it is technically a myelinated tract of the central nervous system, rather than a classical nerve of the peripheral nervous system because it is derived from an out-pouching of the diencephalon (optic stalks) during embryonic development. As a consequence, the fibers of the optic nerve are covered with myelin produced by oligodendrocytes, rather than Schwann cells of the ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Lacrimal Sac
The lacrimal sac or lachrymal sac is the upper dilated end of the nasolacrimal duct, and is lodged in a deep groove formed by the lacrimal bone and frontal process of the maxilla. It connects the lacrimal canaliculi, which drain tears from the eye's surface, and the nasolacrimal duct, which conveys this fluid into the nasal cavity. Lacrimal sac occlusion leads to dacryocystitis. Structure It is oval in form and measures from 12 to 15 mm. in length; its upper end is closed and rounded; its lower is continued into the nasolacrimal duct. Its superficial surface is covered by a fibrous expansion derived from the medial palpebral ligament, and its deep surface is crossed by the lacrimal part of the orbicularis oculi, which is attached to the crest on the lacrimal bone. Histology Like the nasolacrimal duct, the sac is lined by stratified columnar epithelium with mucus-secreting goblet cells, with surrounding connective tissue. The Lacrimal Sac also drains the eye of debris and ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Orbital Nerve Enlargement In IgG4-ROD
Orbital may refer to: Sciences Chemistry and physics * Atomic orbital * Molecular orbital * Hybrid orbital Astronomy and space flight * Orbit ** Earth orbit Medicine and physiology * Orbit (anatomy), also known as the ''orbital bone'' * Orbitofrontal cortex, a part of the brain used for decision making Business * Orbital Corporation, an Australian engine technology company * Orbital Sciences Corporation, a U.S. satellite launch and defense systems corporation * Orbital ATK, American aerospace manufacturer formed from the merger of Orbital Sciences Corporation and parts of Alliant Techsystems Transportation * Ring road (or ''orbital road'' in some regions) * Orbital (metro), a rapid transit line usually encircling a city centre * Orbital engine Other uses * Orbital (The Culture), artificial worlds from Iain M. Banks's series of science fiction novels, the Culture * Orbital (band), an English electronic dance music duo ** ''Orbital'' (1991 album) ** ''Orbital'' (1993 album) * ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Lesions Of Rectus Muscles And Nerves
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classification or naming convention for lesions. Since lesions can occur anywhere in the body and the definition of a lesion is so broad, the varieties of lesions are virtually endless. Generally, lesions may be classified by their patterns, their sizes, their locations, or their causes. They can also be named after the person who discovered them. For example, Ghon lesions, which are found in the lungs of those with tuberculosis, are named after the lesion's discoverer, Anton Ghon. The characteristic skin lesions of a varicella zoster virus infection are called ''chickenpox''. Lesions of the teeth are usually called dental caries. Location Lesions are often classified by their tissue types or locations. For example, a "skin lesion" or a "brain ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Rectus Muscle And Infraorbital Nerve Lesions In IgG4-ROD
"Rectus" is the Latin word meaning "straight" and is used in English to refer to multiple topics in the sciences, including: In molecular chemistry the ''R'' in the ''R'' & ''S'' isomerism stands for "rectus" In grammar "casus rectus" is a formal term for nominative case In mathematics sine is also known as "sinus rectus" In the classification of the animal kingdom it is the systematic taxonomic name of several species, ''e.g.'' campylobacter rectus & syllitus rectus In anatomy it is used to refer to a rectus muscle, primarily ''e.g.'' the "rectus abdominis muscle"; in anatomy it can also refer to: *Inferior rectus muscle *Superior rectus muscle *Lateral rectus muscle *Medial rectus muscle * Musculus rectus thoracis *Rectus capitis lateralis muscle *Rectus femoris muscle The rectus femoris muscle is one of the four quadriceps muscles of the human body. The others are the vastus medialis, the vastus intermedius (deep to the rectus femoris), and the vastus lateralis. All four ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]