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IDEAL Framework
IDEAL (Idea, Development, Exploration, Assessment, Long-term study) is a framework for describing the stages of innovation in surgery and other interventional procedures. The purpose of IDEAL is to improve the quality of research in surgery by emphasizing appropriate methods, transparency of data and rigorous reporting of outcomes. To achieve this, the IDEAL framework provides a set of recommendations for improving the evidence base from research at each stage of innovation, as outlined in the seminal paper published in '' The Lancet'' in 2009. The recommendations emphasize evaluating new procedures prospectively, entering patients and studies into registries and databases to capture all incidences of a procedure, and reporting outcomes by established protocols. It is the first and only such framework for evidence-based practice that was established specifically for surgery and interventional procedures. Background The IDEAL framework was the result of an expert consensus devel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgery
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function, appearance, or to repair unwanted ruptured areas. The act of performing surgery may be called a surgical procedure, operation, or simply "surgery". In this context, the verb "operate" means to perform surgery. The adjective surgical means pertaining to surgery; e.g. surgical instruments or surgical nurse. The person or subject on which the surgery is performed can be a person or an animal. A surgeon is a person who practices surgery and a surgeon's assistant is a person who practices surgical assistance. A surgical team is made up of the surgeon, the surgeon's assistant, an anaesthetist, a circulating nurse and a surgical technologist. Surgery usually spa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgery
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function, appearance, or to repair unwanted ruptured areas. The act of performing surgery may be called a surgical procedure, operation, or simply "surgery". In this context, the verb "operate" means to perform surgery. The adjective surgical means pertaining to surgery; e.g. surgical instruments or surgical nurse. The person or subject on which the surgery is performed can be a person or an animal. A surgeon is a person who practices surgery and a surgeon's assistant is a person who practices surgical assistance. A surgical team is made up of the surgeon, the surgeon's assistant, an anaesthetist, a circulating nurse and a surgical technologist. Surgery usually spa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Medical Journal
''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Originally called the ''British Medical Journal'', the title was officially shortened to ''BMJ'' in 1988, and then changed to ''The BMJ'' in 2014. The journal is published by BMJ Publishing Group Ltd, a subsidiary of the British Medical Association (BMA). The editor-in-chief of ''The BMJ'' is Kamran Abbasi, who was appointed in January 2022. History The journal began publishing on 3 October 1840 as the ''Provincial Medical and Surgical Journal'' and quickly attracted the attention of physicians around the world through its publication of high-impact original research articles and unique case reports. The ''BMJ''s first editors were P. Hennis Green, lecturer on the diseases of children at the Hunterian School of Medicine, who also was its f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not directly related to food or drugs, but involves such things as regulating lasers, cellular phones, and condoms, as well as control of disease in contexts varying from h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Comorbidities
In medicine, comorbidity - from Latin morbus ("sickness"), co ("together"), -ity (as if - several sicknesses together) - is the presence of one or more additional conditions often co-occurring (that is, concomitant or concurrent) with a primary condition. Comorbidity describes the effect of all other conditions an individual patient might have other than the primary condition of interest, and can be physiological or psychological. In the context of mental health, comorbidity often refers to disorders that are often coexistent with each other, such as depression and anxiety disorders. The concept of multimorbidity is related to comorbidity but presents a different meaning and approach. Definition The term "comorbid" has three definitions: # to indicate a medical condition existing simultaneously but independently with another condition in a patient. # to indicate a medical condition in a patient that causes, is caused by, or is otherwise related to another condition in the same ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Randomized Controlled Trial
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By Random assignment, randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing Standard of care#Medical standard of care, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CUSUM
In statistical quality control, the CUsUM (or cumulative sum control chart) is a sequential analysis technique developed by E. S. Page of the University of Cambridge. It is typically used for monitoring change detection. CUSUM was announced in Biometrika, in 1954, a few years after the publication of Wald's sequential probability ratio test (SPRT). E. S. Page referred to a "quality number" \theta, by which he meant a parameter of the probability distribution; for example, the mean. He devised CUSUM as a method to determine changes in it, and proposed a criterion for deciding when to take corrective action. When the CUSUM method is applied to changes in mean, it can be used for step detection of a time series. A few years later, George Alfred Barnard developed a visualization method, the V-mask chart, to detect both increases and decreases in \theta. Method As its name implies, CUSUM involves the calculation of a cumulative sum (which is what makes it "sequential"). Samples from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
STROBE
A strobe light or stroboscopic lamp, commonly called a strobe, is a device used to produce regular flashes of light. It is one of a number of devices that can be used as a stroboscope. The word originated from the Ancient Greek ('), meaning "act of whirling". A typical commercial strobe light has a flash energy in the region of 10 to 150 joules, and discharge times as short as a few milliseconds, often resulting in a flash power of several kilowatts. Larger strobe lights can be used in “continuous” mode, producing extremely intense illumination. The light source is commonly a xenon flash lamp, or ''flashtube'', which has a complex spectrum and a color temperature of approximately 5,600 kelvins. To obtain colored light, colored gels may be used. Scientific explanation of flashtubes Strobe lights usually use flashtubes with energy supplied from a capacitor, an energy storage device much like a battery, but capable of charging and releasing energy much faster. In a ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doug Altman
Douglas Graham Altman FMedSci (12 July 1948 – 3 June 2018) was an English statistician best known for his work on improving the reliability and reporting of medical research and for highly cited papers on statistical methodology. He was professor of statistics in medicine at the University of Oxford, founder and Director of Centre for Statistics in Medicine and Cancer Research UK Medical Statistics Group, and co-founder of the international Equator Network for health research reliability. Professional career Doug Altman graduated in 1970 with an Honours degree in Statistics from Bath University of Technology, now the University of Bath. His first job was in the Department of Community Medicine, St Thomas’s Hospital Medical School, London. He then spent 11 years working for the Medical Research Council's Clinical Research Centre where he worked almost entirely as a statistical consultant in a wide variety of medical areas. In 1988 Doug Altman became head of the newly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paper
Paper is a thin sheet material produced by mechanically or chemically processing cellulose fibres derived from wood, rags, grasses or other vegetable sources in water, draining the water through fine mesh leaving the fibre evenly distributed on the surface, followed by pressing and drying. Although paper was originally made in single sheets by hand, almost all is now made on large machines—some making reels 10 metres wide, running at 2,000 metres per minute and up to 600,000 tonnes a year. It is a versatile material with many uses, including printing, painting, graphics, signage, design, packaging, decorating, writing, and cleaning. It may also be used as filter paper, wallpaper, book endpaper, conservation paper, laminated worktops, toilet tissue, or currency and security paper, or in a number of industrial and construction processes. The papermaking process developed in east Asia, probably China, at least as early as 105 CE, by the Han court eunuch Cai Lun, although the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muir Gray
Sir John Armstrong Muir Gray is a British physician, who has held senior positions in screening, public health, information management. and value in healthcare. He is currently the Chief Knowledge Officer for EXi, a digital health therapeutic prescribing exercise to people with or at risk of up to 23 long-term health conditions. He was director of Research and Development for Anglia and Oxford Regional Health Authority and supported the United Kingdom Centre of the Cochrane Collaboration in promoting evidence-based medicine. He held the positions of director at the UK National Screening Committee, during which he helped pioneer Britain's breast and cervical cancer screening programmes, and National Library for Health, and director of Clinical Knowledge Process and Safety for the NHS National Programme for IT. He was knighted in 2005 for the development of the foetal, maternal and child screening programme and the creation of the National Library for Health. He was the dire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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