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IstR RNA
The TisB-IstR toxin-antitoxin system is the first known toxin-antitoxin system which is induced by the SOS response in response to DNA damage. IstR-1 and IstR-2 IstR sRNA (inhibitor of SOS-induced toxicity by RNA) is a family of non-coding RNA first identified in ''Escherichia coli''. There are two small RNAs encoded by the IstR locus: IstR-1 and IstR-2, of which IstR-1 works as antitoxins against the toxic proteinbr>TisB(toxicity-induced by SOS B) which is encoded by the neighbouring ''tisAB'' gene. IstR-1 is a 75 nucleotide transcript expressed constitutively throughout growth, whereas IstR-2 is a 140 nucleotide transcript induced by Mitomycin C (MMC). Both IstR-2 and ''tisAB'' are thought to be regulated by LexA while IstR-1 is constitutively transcribed. Deletion analysis confirmed the function of IstR, ''E. coli'' strain K-12 could not grow in the absence of IstR when ''tisAB'' was present. Inserting IstR genes on a plasmid allowed the bacteria to grow normally. Further studi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enterobacteriaceae
Enterobacteriaceae is a large family (biology), family of Gram-negative bacteria. It was first proposed by Rahn in 1936, and now includes over 30 genera and more than 100 species. Its classification above the level of family is still a subject of debate, but one classification places it in the order Enterobacterales of the class Gammaproteobacteria in the phylum Pseudomonadota. In 2016, the description and members of this family were emended based on comparative genomic analyses by Adeolu et al. Enterobacteriaceae includes, along with many harmless Symbiosis, symbionts, many of the more familiar pathogenic bacteria, pathogens, such as ''Salmonella'', ''Escherichia coli'', ''Klebsiella'', and ''Shigella''. Other disease-causing bacteria in this family include ''Enterobacter'' and ''Citrobacter''. Members of the Enterobacteriaceae can be Bacterial taxonomy#Nomenclature, trivially referred to as enterobacteria or "enteric bacteria",as several members live in the intestines of anim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |