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Isothiazolone
Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole. Isothiazolone itself is of limited interest, but several of its derivatives are widely used preservatives and antimicrobials. Synthesis Compared to many other simple heterocycles, the discovery of isothiazolinone is fairly recent, with reports first appearing in the 1960s. Isothiazolinones can be prepared on an industrial scale by the ring-closure of 3-mercaptopropanamides. These in turn are produced from acrylic acid via the 3-mercaptopropionic acid: : Ring-closure of the thiol-amide is typically effected by chlorination or oxidation of the 3-sulfanylpropanamide to the corresponding disulfide. : Many other routes have been developed, including addition of thiocyanate to propargyl amides. Mechanism of action The antimicrobial activity of isothiazolinones is attributed to their ability to inhibit life-sustaining enzymes, speci ...
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Isothiazolinone Synth (part 1)
Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole. Isothiazolone itself is of limited interest, but several of its derivatives are widely used preservatives and antimicrobials. Synthesis Compared to many other simple heterocycles, the discovery of isothiazolinone is fairly recent, with reports first appearing in the 1960s. Isothiazolinones can be prepared on an industrial scale by the ring-closure of 3-mercaptopropanamides. These in turn are produced from acrylic acid via the 3-Mercaptopropionic acid, 3-mercaptopropionic acid: : Ring-closure of the thiol-amide is typically effected by chlorination or oxidation of the 3-sulfanylpropanamide to the corresponding disulfide. : Many other routes have been developed, including addition of thiocyanate to propargyl amides. Mechanism of action The antimicrobial activity of isothiazolinones is attributed to their ability to inhibit life ...
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Isothiazolinone Synth (part 2)
Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole. Isothiazolone itself is of limited interest, but several of its derivatives are widely used preservatives and antimicrobials. Synthesis Compared to many other simple heterocycles, the discovery of isothiazolinone is fairly recent, with reports first appearing in the 1960s. Isothiazolinones can be prepared on an industrial scale by the ring-closure of 3-mercaptopropanamides. These in turn are produced from acrylic acid via the 3-mercaptopropionic acid: : Ring-closure of the thiol-amide is typically effected by chlorination or oxidation of the 3-sulfanylpropanamide to the corresponding disulfide. : Many other routes have been developed, including addition of thiocyanate to propargyl amides. Mechanism of action The antimicrobial activity of isothiazolinones is attributed to their ability to inhibit life-sustaining enzymes, speci ...
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Methylchloroisothiazolinone
Methylchloroisothiazolinone, also referred to as MCI, is the organic compound with the formula S(C2HCl)C(O)N(CH3). It is a white solid that melts near room temperature. The compound is an isothiazolinone, a class of heterocycles used as biocides. These compounds have an active sulphur moiety that is able to oxidize thiol-containing residues, thereby effectively killing most aerobic and anaerobic bacteria. MCI is often used in combination with methylisothiazolinone, a mixture known as Kathon. The isothiazolinones have attracted attention because they can cause contact dermatitis. Methylchloroisothiazolinone is effective against gram-positive and gram-negative bacteria, yeast, and fungi. Application Methylchloroisothiazolinone is found in many water-based personal care products and cosmetics. Methylchloroisothiazolinone was first used in cosmetics in the 1970s. It is also used in glue production, detergents, paints, fuels, and other industrial processes. Methylchloroisothiazolinon ...
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Chloromethylisothiazolinone
Methylchloroisothiazolinone, also referred to as MCI, is the organic compound with the formula S(C2HCl)C(O)N(CH3). It is a white solid that melts near room temperature. The compound is an isothiazolinone, a class of heterocycles used as biocides. These compounds have an active sulphur moiety that is able to oxidize thiol-containing residues, thereby effectively killing most aerobic and anaerobic bacteria. MCI is often used in combination with methylisothiazolinone, a mixture known as Kathon. The isothiazolinones have attracted attention because they can cause contact dermatitis. Methylchloroisothiazolinone is effective against gram-positive and gram-negative bacteria, yeast, and fungi. Application Methylchloroisothiazolinone is found in many water-based personal care products and cosmetics. Methylchloroisothiazolinone was first used in cosmetics in the 1970s. It is also used in glue production, detergents, paints, fuels, and other industrial processes. Methylchloroisothiazolinone ...
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Methylisothiazolinone
Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3. It is a white solid. Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications. MIT and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis. Preparation It is prepared by cyclization of ''cis''-N-methyl-3-thiocyanoacrylamide: : NCSCH=CHC(O)NHCH3 -> SCH=CHC(O)NCH3 + HCN Applications Methylisothiazolinone is used for controlling microbial growth in water-containing solutions. It is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT) sold commercially as ''Kathon''. Kathon is supplied to manufacturers as a concentrated stock solution containing from 1.5–15% of CMIT/MIT. Kathon also has been used to control slime in the manufacture of paper products that contact food. In addition, this product serves ...
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Benzisothiazolinone
Benzisothiazolinone (BIT) is an organic compound with the formula C6H4SN(H)CO. A white solid, it is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones. BIT is widely used as a preservative and antimicrobial. Usage Benzisothiazolinone has a microbicide and a fungicide mode of action. It is widely used as a preservative, for example in: * emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions * home cleaning and car care products; laundry detergents, stain removers and fabric softeners; * industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins * agriculture in pesticide formulations * gas and oil drilling in muds and packer fluids preservation. In paints, it is commonly used alone or as a mixture with methylisothiazolinone. Typical concentrations in products are 200–400  ppm depending on the application a ...
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Organic Compound
In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, hydrogen cyanide), are not classified as organic compounds and are considered inorganic. Other than those just named, little consensus exists among chemists on precisely which carbon-containing compounds are excluded, making any rigorous definition of an organic compound elusive. Although organic compounds make up only a small percentage of Earth's crust, they are of central importance because all known life is based on organic compounds. Living t ...
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Fuel Tank
A fuel tank (also called a petrol tank or gas tank) is a safe container for flammable fluids. Though any storage tank for fuel may be so called, the term is typically applied to part of an engine system in which the fuel is stored and propelled (fuel pump) or released (pressurized gas) into an engine. Fuel tanks range in size and complexity from the small plastic tank of a butane lighter to the multi-chambered cryogenic Space Shuttle external tank. Uses Typically, a fuel tank must allow or provide the following: * Storage of fuel: the system must contain a given quantity of fuel and must avoid leakage and limit evaporative emissions. * Filling: the fuel tank must be filled in a secure way, without sparks. * Provide a method for determining level of fuel in tank, gauging (the remaining quantity of fuel in the tank must be measured or evaluated). * Venting (if over-pressure is not allowed, the fuel vapors must be managed through valves). * Feeding of the engine (throug ...
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Pulp Mill
A pulp mill is a manufacturing facility that converts wood chips or other plant fiber sources into a thick fiber board which can be shipped to a paper mill for further processing. Pulp can be manufactured using mechanical, semi-chemical, or fully chemical methods ( kraft and sulfite processes). The finished product may be either bleached or non-bleached, depending on the customer requirements. Wood and other plant materials used to make pulp contain three main components (apart from water): cellulose fibres (desired for papermaking), lignin (a three-dimensional polymer that binds the cellulose fibres together) and hemicelluloses, (shorter branched carbohydrate polymers). The aim of pulping is to break down the bulk structure of the fiber source, be it chips, stems or other plant parts, into the constituent fibers. Chemical pulping achieves this by degrading the lignin and hemicellulose into small, water-soluble molecules that can be washed away from the cellulose fibers with ...
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Paper Mill
A paper mill is a factory devoted to making paper from vegetable fibres such as wood pulp, old rags, and other ingredients. Prior to the invention and adoption of the Fourdrinier machine and other types of paper machine that use an endless belt, all paper in a paper mill was made by hand, one sheet at a time, by specialized laborers. History Historical investigations into the origin of the paper mill are complicated by differing definitions and loose terminology from modern authors: Many modern scholars use the term to refer indiscriminately to all kinds of mills, whether powered by humans, by animals or by water. Their propensity to refer to any ancient paper manufacturing center as a "mill", without further specifying its exact power source, has increased the difficulty of identifying the particularly efficient and historically important water-powered type. Human and animal-powered mills The use of human and animal powered mills was known to Muslim and Chinese paperma ...
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Wood Preservation
Wood easily degrades without sufficient preservation. Apart from structural wood preservation measures, there are a number of different chemical preservatives and processes (also known as "timber treatment", "lumber treatment" or "pressure treatment") that can extend the life of wood, timber, and their associated products, including engineered wood. These generally increase the durability and resistance from being destroyed by insects or fungi. History As proposed by Richardson, treatment of wood has been practiced for almost as long as the use of wood itself. There are records of wood preservation reaching back to ancient Greece during Alexander the Great's rule, where bridge wood was soaked in olive oil. The Romans protected their ship hulls by brushing the wood with tar. During the Industrial Revolution, wood preservation became a cornerstone of the wood processing industry. Inventors and scientists such as Bethell, Boucherie, Burnett and Kyan made historic developments in wo ...
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Oil Extraction
Petroleum is a fossil fuel that can be drawn from beneath the earth's surface. Reservoirs of petroleum was formed through the mixture of plants, algae, and sediments in shallow seas under high pressure. Petroleum is mostly recovered from oil drilling. Seismic surveys and other methods are used to locate oil reservoirs. Oil rigs and oil platforms are used to drill long holes into the earth to create an oil well and extract petroleum. After extraction, oil is refined to make gasoline and other products such as tires and refrigerators. Extraction of petroleum can be dangerous and have led to oil spills. Locating the oil field Geologists and geophysicists use seismic surveys to search for geological structures that may form oil reservoirs. The "classic" method includes making an underground explosion nearby and observing the seismic response, which provides information about the geological structures underground. However, "passive" methods that extract information from naturally occ ...
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