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Isao Arita
Isao Arita (born 1926) is a Japanese physician, virologist and vaccination specialist who headed the World Health Organization (WHO) Smallpox Eradication Unit in 1977–85. During this period, smallpox became the first infectious disease of humans to be eradicated globally. For this work, he and his colleagues were awarded the Japan Prize in 1988. He also advised the successful programme to eradicate poliovirus from the Western Pacific region. Education and early career Arita was born in Kumamoto, southern Japan, in 1926. After gaining his medical degree from Kumamoto Medical School in 1950, he spent a decade working for the Japanese Ministry of Health and Welfare as a medical officer in the Infectious Disease Control section.Fenner 2006, p. 144 For part of this time he worked on vaccine control and standardisation, an area in which he received training at the Paul Ehrlich Institute in Germany. Smallpox eradication programme Arita's work for the WHO smallpox eradication program ...
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Kumamoto
is the capital city of Kumamoto Prefecture on the island of Kyushu, Japan. , the city has an estimated population of 738,907 and a population density of 1,893 people per km2. The total area is 390.32 km2. had a population of 1,461,000, as of the 2000 census. , Kumamoto Metropolitan Employment Area has a GDP of US$39.8 billion. It is not considered part of the Fukuoka–Kitakyushu metropolitan area, despite their shared border. The city was designated on April 1, 2012, by government ordinance. History Early modern period Shokuhō period Katō Kiyomasa, a contemporary of Toyotomi Hideyoshi, was made ''daimyō'' of half of the (old) administrative region of Higo in 1588. Afterwards, Kiyomasa built Kumamoto Castle. Due to its many innovative defensive designs, Kumamoto Castle was considered impenetrable, and Kiyomasa enjoyed a reputation as one of the finest castle-builders in Japanese history. Edo period After Kiyomasa died in 1611, his son, Tadahiro, succeeded him. ...
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Monkeypox Virus
''Monkeypox virus'' (MPV, MPXV, or hMPXV) is a species of double-stranded DNA virus that causes monkeypox in humans and other mammals. Monkeypox virus is a zoonotic virus belonging to the ''orthopoxvirus'' genus, making it closely related to the variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. MPV is oval-shaped with a lipoprotein outer membrane. The genome is approximately 190 kb. The variola and monkeypox virus are both orthopoxviruses, and so the smallpox vaccine is effective against monkeypox if given within 3–5 years before contracting the disease. The clinical presentation of Monkeypox is similar to smallpox, but with a milder rash and lower mortality rate. The virus is transmissible between animals and humans, by direct contact to the lesions or bodily fluids. Monkeypox was given its name after being isolated from monkeys, but the majority of the carriers of this virus are rodents. Variation in virulence of the virus has been observed in isolates from Central A ...
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Ciro A
Ciro may refer to: * Ciro (given name), a list of the people who share the Italian and Spanish given name *Ćiro (given name), a list of the people who share the Croatian given name *Ciro (opera), 1654 opera by Francesco Cavalli *Cyrus Cuneo (1879-1916), Italian American artist who was generally known as Ciro See also *Cirò (other) *Ciro's Ciro's (later known as Ciro's Le Disc) was a nightclub on Sunset Boulevard in West Hollywood, California owned by William Wilkerson. Opened in 1940, Ciro's became a popular nightspot for celebrities. The nightclub closed in 1957 and was reopened ...
, nightclub {{disambig ...
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Frederick C
Frederick may refer to: People * Frederick (given name), the name Nobility Anhalt-Harzgerode *Frederick, Prince of Anhalt-Harzgerode (1613–1670) Austria * Frederick I, Duke of Austria (Babenberg), Duke of Austria from 1195 to 1198 * Frederick II, Duke of Austria (1219–1246), last Duke of Austria from the Babenberg dynasty * Frederick the Fair (Frederick I of Austria (Habsburg), 1286–1330), Duke of Austria and King of the Romans Baden * Frederick I, Grand Duke of Baden (1826–1907), Grand Duke of Baden * Frederick II, Grand Duke of Baden (1857–1928), Grand Duke of Baden Bohemia * Frederick, Duke of Bohemia (died 1189), Duke of Olomouc and Bohemia Britain * Frederick, Prince of Wales (1707–1751), eldest son of King George II of Great Britain Brandenburg/Prussia * Frederick I, Elector of Brandenburg (1371–1440), also known as Frederick VI, Burgrave of Nuremberg * Frederick II, Elector of Brandenburg (1413–1470), Margrave of Brandenburg * Frederick William, Elector ...
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Science (journal)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' c ...
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Poliovirus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different teams ...
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Morihiro Hosokawa
is a Japanese politician and Nobility, noble who was Prime Minister of Japan from 1993 to 1994, leading a coalition government which was the first non-Liberal Democratic Party (Japan), Liberal Democratic Party (LDP) government of Japan since 1955. After a funding scandal in early 1994, he was forced to resign. He later ran unsuccessfully as a candidate for Governor of Tokyo in the 2014 Tokyo gubernatorial election, February 2014 gubernatorial election as an independent supported by the Democratic Party of Japan. He has been, since 2005, the head of the Hosokawa clan, Kumamoto-Hosokawa clan, one of the noble families of Japan. Early life Morihiro Hosokawa was born in Tokyo as the eldest grandson of Moritatsu, 3rd Marquess Hosokawa, and head of the Hosokawa clan. His maternal grandfather is the pre-war prime minister Prince Fumimaro Konoe. As a great-great-grandson of Prince Kuni Asahiko, he is a third cousin of the present emperor, Naruhito. He is also a descendant of Christian h ...
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Frank Fenner
Frank John Fenner (21 December 1914 – 22 November 2010) was an Australian scientist with a distinguished career in the field of virology. His two greatest achievements are cited as overseeing the eradication of smallpox, and the attempted control of Australia's rabbit plague through the introduction of ''Myxoma virus''. The Australian Academy of Science awards annually the prestigious Fenner Medal for distinguished research in biology by a scientist under 40 years of age. Early life and education Frank Johannes Fenner was born in Ballarat in 1914. The family moved to Adelaide, South Australia in November 1916. He attended Rose Park Primary School and Thebarton Technical School. He attended the University of Adelaide, where he earned degrees in medicine and surgery in 1938. That year, uneasy about Hitler's rise, he legally changed his middle name to John. Career In May 1937, Fenner was a member of an Adelaide University anthropological expedition to Nepabunna Mission in the ...
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International Security (journal)
''International Security'' is a peer-reviewed academic journal in the field of international security, international and national security. It was founded in 1976 and is edited by the Belfer Center for Science and International Affairs at Harvard University and published four times a year by MIT Press, both of Cambridge, Massachusetts, Cambridge, Massachusetts. The current editor-in-chief is Steven E. Miller (Harvard University). ''International Security'' is considered among the leading journals in the field of ''International Relations''. According to the ''Journal Citation Reports'', the journal has a 2017 impact factor of 4.135, ranking it 2nd out of 85 journals in the category "International Relations". Along with the journal ''Security Studies (journal), Security Studies'', it is the most prominent journal dedicated to security studies. Articles in ''International Security'' tend to deploy qualitative methods, in particular qualitative historical analysis. Articles are also ...
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Variola Virus
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their sk ...
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Ali Maow Maalin
Ali Maow Maalin ( so, Cali Macow Macallin; also Mao Moallim and Mao' Mo'allim; 1954 – 22 July 2013) was a Somali hospital cook and health worker from Merca who is the last person known to have been infected with naturally occurring ''Variola minor'' smallpox. He was diagnosed with the disease in October 1977 and made a full recovery. Although he had many contacts, none of them developed the disease, and an aggressive containment campaign was successful in preventing an outbreak. Smallpox was declared to have been eradicated globally by the World Health Organization (WHO) two years later. Maalin was subsequently involved in the successful poliomyelitis eradication campaign in Somalia, and he died of malaria while carrying out polio vaccinations after the re-emergence of the poliovirus in 2013. Smallpox eradication in Africa Smallpox is an infectious disease caused by two strains of virus, ''Variola major'' and ''V. minor''. ''V. minor'' is the rarer of the two strains, and caus ...
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Ethiopian–Somali Conflict
The Ethiopian–Somali conflict is a territorial and political dispute between the countries of Ethiopia and Somalia. Lasting from the late 1940s, when the Ogaden region was handed back over to Ethiopia by the British, into the present day, the tensions culminated in List of Ethiopian-Somali wars and conflicts, three wars and numerous military clashes alongside the borders. However, because of the Somali Civil War and the lack of a functioning central government in Somalia since the Somali Rebellion, collapse of the Democratic Republic of Somalia in 1991, Ethiopia has the upper hand militarily and economically. Background During the 16th century, Imam Ahmad ibn Ibrahim al-Ghazi (Ahmad Gurey or Gragn) led a Abyssinian–Adal war, Conquest of Abyssinia (''Futuh al-Habash''), which brought three-quarters of the Christians, Christian polity under the power of the Muslim Adal Sultanate. With an army mainly composed of Somali people, Somalis, Al-Ghazi's forces and their Ottoman Empire, ...
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