International Consensus Criteria
Clinical descriptions of chronic fatigue syndrome (CFS) vary. Different groups have produced sets of diagnostic criteria that share many similarities. The biggest differences between criteria are whether post-exertional malaise (PEM) is required, and the number of symptoms needed. Aspects of the condition are controversial, with disagreements over etiology, pathophysiology, treatment and naming between medical practitioners, researchers, patients and advocacy groups. Furthermore, diagnosing CFS can be difficult due to several factors, including lack of a standard test and non-specific symptoms. Subgroup analysis suggests that, depending on the applied definition, CFS may represent a variety of conditions rather than a single disease entity. Definitions 2015 IOM criteria The IOM criteria come from the IOM's 2015 report on CFS, and the CDC currently uses this definition. The IOM criteria require the following three symptoms: * Severe, disabling fatigue of new onset * Post-exer ...
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