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Instituto Bioclon
The Instituto Bioclon S.A. de C.V. (Bioclon Institute) was formed in 1990 to research and develop F(ab’)2 antivenoms. On May 6, 2015 they received approval from the FDA to commercialize Anavip becoming their second drug approved by the FDA after ANASCORP. Both are commercialized in the US by Rare Disease Therapeutics, Inc. The company is performing clinical trials to get approval for a third drug, ANALATRO, designed to treat black widow spider envenomation. Operations The Instituto Bioclon is located in Mexico City, Mexico and has a Certificación Internacional de Buenas Prácticas de Manufactura (International Certificate for Good Manufacturing Practices) which was granted to Bioclon by the , (INVIMA) (National Food and Drug Monitoring Institute), of the Ministry of Health and Social Protection of Colombia, as well as by COFEPRIS, in Mexico. Products * Anavip – timber rattlesnake antivenom *Coralmyn – coral snake antivenom * Antivipmyn – pit viper antivenom * Antivipm ...
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Mexico City
Mexico City ( es, link=no, Ciudad de México, ; abbr.: CDMX; Nahuatl: ''Altepetl Mexico'') is the capital and largest city of Mexico, and the most populous city in North America. One of the world's alpha cities, it is located in the Valley of Mexico within the high Mexican central plateau, at an altitude of . The city has 16 boroughs or ''demarcaciones territoriales'', which are in turn divided into neighborhoods or ''colonias''. The 2020 population for the city proper was 9,209,944, with a land area of . According to the most recent definition agreed upon by the federal and state governments, the population of Greater Mexico City is 21,804,515, which makes it the sixth-largest metropolitan area in the world, the second-largest urban agglomeration in the Western Hemisphere (behind São Paulo, Brazil), and the largest Spanish language, Spanish-speaking city (city proper) in the world. Greater Mexico City has a gross domestic product, GDP of $411 billion in 2011, which makes ...
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Pit Viper
The Crotalinae, commonly known as pit vipers,Mehrtens JM (1987). ''Living Snakes of the World in Color''. New York: Sterling Publishers. 480 pp. . crotaline snakes (from grc, κρόταλον ''krotalon'' castanet), or pit adders, are a subfamily of vipers found in Eurasia and the Americas. Like all other vipers, they are venomous. They are distinguished by the presence of a heat-sensing pit organ located between the eye and the nostril on both sides of the head. Currently, 23 genera and 155 species are recognized: These are also the only viperids found in the Americas. The groups of snakes represented here include rattlesnakes, lanceheads, and Asian pit vipers. The type genus for this subfamily is ''Crotalus'', of which the type species is the timber rattlesnake, ''C. horridus''. These snakes range in size from the diminutive hump-nosed viper, ''Hypnale hypnale'', that grows to a typical total length (including tail) of only , to the bushmaster, ''Lachesis muta'', a specie ...
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Organizations Based In Mexico City
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includi ...
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Toxicology Organizations
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neoclas ...
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Latrodectus
''Latrodectus'' is a broadly distributed genus of spiders with several species that are commonly known as the true widows. This group is composed of those often loosely called black widow spiders, brown widow spiders, and similar spiders. However, the diversity of species is much greater. A member of the family Theridiidae, this genus contains 34 species, which include several North American "black widows" (southern black widow ''Latrodectus mactans'', western black widow ''Latrodectus hesperus'', and northern black widow ''Latrodectus variolus''). Besides these, North America also has the red widow ''Latrodectus bishopi'' and the brown widow ''Latrodectus geometricus'', which, in addition to North America, has a much wider geographic distribution. Elsewhere, others include the European black widow (''Latrodectus tredecimguttatus''), the Australian redback black widow (''Latrodectus hasseltii'') and the closely related New Zealand katipō (''Latrodectus katipo''), several differ ...
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Brown Recluse
The brown recluse (''Loxosceles reclusa''), Sicariidae (formerly placed in a family "Loxoscelidae") is a recluse spider with Necrosis, necrotic venom. Similar to those of other recluse spiders, their bites sometimes require medical attention. The brown recluse is one of three spiders in North America with list of medically significant spider bites, medically significant venom, the others being the Latrodectus, black widow and the Loxosceles laeta, Chilean recluse. Brown recluse spiders are usually between , but may grow larger. While typically light to medium brown, they range in color from whitish to dark brown or blackish gray. The cephalothorax and abdomen are not necessarily the same color. These spiders usually have markings on the Dorsum (biology), dorsal side of their cephalothorax, with a black line coming from it that looks like a violin with the neck of the violin pointing to the rear of the spider, resulting in the nicknames fiddleback spider, brown fiddler, or violin ...
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Scorpion
Scorpions are predatory arachnids of the order Scorpiones. They have eight legs, and are easily recognized by a pair of grasping pincers and a narrow, segmented tail, often carried in a characteristic forward curve over the back and always ending with a stinger. The evolutionary history of scorpions goes back 435 million years. They mainly live in deserts but have adapted to a wide range of environmental conditions, and can be found on all continents except Antarctica. There are over 2,500 described species, with 22 extant (living) families recognized to date. Their taxonomy is being revised to account for 21st-century genomic studies. Scorpions primarily prey on insects and other invertebrates, but some species hunt vertebrates. They use their pincers to restrain and kill prey, or to prevent their own predation. The venomous sting is used for offense and defense. During courtship, the male and female grasp each other's pincers and dance while he tries to move her onto his s ...
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