Imidapril
Imidapril (trade name Tanatril) is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. It was patented in 1982 and approved for medical use in 1993. Contraindications Contraindications are hypersensitivity against ACE inhibitors, especially if it has resulted in angioedema; idiopathic or hereditary angioedema; kidney failure; the second and third trimesters in pregnancy; and combination with the drug aliskiren in people with diabetes. Adverse effects Common adverse effects are similar to other antihypertensive drugs and include headache, vertigo, and drowsiness. A dry cough is common as with all ACE inhibitors. Other possible adverse effects are described at ACE inhibitor#Adverse effects. Interactions No interaction studies have been conducted except with digoxin, which slightly decreases imidapril levels, possibly because it reduces its absorption from the gut. Other potential interactions are not well studied: Rifampicin re ...
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