Icosanoyl-CoA Synthase
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Icosanoyl-CoA Synthase
In enzymology, an icosanoyl-CoA synthase () is an enzyme that catalyzes the chemical reaction :stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ \rightleftharpoons icosanoyl-CoA + CO2 + CoA + 2 NAD(P)+ + H2O The 5 substrates of this enzyme are stearoyl-CoA, malonyl-CoA, NADH, NADPH, and H+, whereas its 6 products are icosanoyl-CoA, CO2, CoA, NAD+, NADP+, and H2O. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). Other names in common use include acyl-CoA elongase, C18-CoA elongase, and stearoyl-CoA elongase. ...
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Enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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