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Heteroscorpine
Heteroscopine (HS-1) is the main component of the venom of '' Heterometrus laoticus''. It belongs to the Scorpine toxin family. It is a polypeptide consisting of a defensin-like component on its N-terminal end and a putative potassium channel blocking component on its C-terminal end. It has antimicrobial effect on some bacteria, but not on fungi. Sources Heteroscorpine (HS-1) is a component of the venom of the Thai giant scorpion '' Heterometrus laoticus''. This species is a member of the scorpion family commonly known as giant forest scorpions, indigenous to large parts of South and South-East Asia. Chemistry The gene coding for HS-1 consists of one intron flanked by two exons. HS-1 is a polypeptide consisting of 95 amino acids. The HS-1 protein has a large resemblance to other toxins of the Scorpine family (which is a subgroup of the Beta-KTx toxin family). The polypeptides of the Scorpine family possess two structural and functional domains: a N-terminal α-helix (which h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterometrus
''Heterometrus'', whose members are also known by the collective vernacular name giant forest scorpions, is a genus of scorpions belonging to the family Scorpionidae. It is distributed widely across tropical and subtropical southeastern Asia, including Indonesia, Brunei, Malaysia, Myanmar, Philippines, Singapore, Cambodia, Laos, Thailand, Vietnam, India ( Nicobar Islands, Andaman Islands), and China (Hainan). It is notable for containing some of the largest living species of scorpions. Taxonomy The genus was introduced by C.G. Ehrenberg (in Hemprich & Ehrenberg, 1828), originally as a subgenus of the genus '' Buthus''. It was elevated to genus rank by F. Karsch in 1879. H.W.C. Couzijn (1978, 1981) subdivided the genus into several subgenera, but F. Kovařík (2004) synonymized these subgenera with the nominal genus. In 2020 the genus was reviewed by L. Prendini & S. F. Loria, three of the former subgenera were revalidated and elevated to genera and one valid subgenus was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterometrus Laoticus
''Heterometrus laoticus'' or Vietnam forest scorpion, is a scorpion species found in peaty areas of Vietnam and Laos. They can reach lengths of . They are a communal species, but cannibalism has been known to occur, and if caught, they can be extremely violent even towards their own kind. Lethality Rather than being a lethal toxin, the giant scorpion's venom is paralytic. The venom is distilled into medicines against various kinds of microorganisms. It exhibits good results in disc diffusion assay for ''Bacillus subtilis'', ''Klebsiella pneumoniae'', ''Pseudomonas aeruginosa'', and ''Staphylococcus aureus'', among others. As food The scorpion is farmed for consumption as a novelty food in Vietnam. They are also used to make snake wine Snake wine (; vi, rượu rắn; km, ស្រាពស់, ) is an alcoholic beverage produced by infusing whole snakes in rice wine or grain alcohol. The drink was first recorded to have been consumed in China during the Western Zhou dynast ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Defensin
Defensins are small cysteine-rich cationic proteins across cellular life, including vertebrate Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, ... and invertebrate animals, plants, and fungi. They are host defense peptides, with members displaying either direct Antimicrobial peptides, antimicrobial activity, Immune system, immune signalling activities, or both. They are variously active against bacteria, fungus, fungi and many enveloped and nonenveloped viruses. They are typically 18-45 amino acids in length, with three or four highly conserved disulphide bonds. In animals, they are produced by cells of the innate immune system and epithelial cells, whereas in plants and fungi they are produced by a wide variety of tissues. An organism usually produces many different defensins, some ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Potassium Channel
Potassium channels are the most widely distributed type of ion channel found in virtually all organisms. They form potassium-selective pores that span cell membranes. Potassium channels are found in most cell types and control a wide variety of cell functions. Function Potassium channels function to conduct potassium ions down their electrochemical gradient, doing so both rapidly (up to the diffusion rate of K+ ions in bulk water) and selectively (excluding, most notably, sodium despite the sub-angstrom difference in ionic radius). Biologically, these channels act to set or reset the resting potential in many cells. In excitable cells, such as neurons, the delayed counterflow of potassium ions shapes the action potential. By contributing to the regulation of the cardiac action potential duration in cardiac muscle, malfunction of potassium channels may cause life-threatening arrhythmias. Potassium channels may also be involved in maintaining vascular tone. They also regulate ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emperor Scorpion
The emperor scorpion, ''Pandinus imperator'', is a species of scorpion native to rainforests and savannas in West Africa. It is one of the largest scorpions in the world and lives for 6–8 years. Its body is black, but like other scorpions it glows pastel green or blue under ultraviolet light. It is a popular species in the pet trade, and is protected by CITES to prevent over-collecting that might impact the species' survival. Description The emperor scorpion (''Pandinus imperator'') is one of the largest species of scorpion in the world, with adults averaging about in length and a weight of 30 g. However, some species of forest scorpions are fairly similar to the emperor scorpion in size, and one scorpion, ''Heterometrus swammerdami'', holds the record for being the world's largest scorpion at 9 inches (23 cm) in length. The large pincers are blackish-red and have a granular texture. The front part of the body, or prosoma, is made up of four sections, each with a p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Opistophthalmus Carinatus
The robust burrowing scorpion (''Opistophthalmus carinatus'') is a widespread species of scorpion in the drier regions of southern Africa. It is a burrowing An Eastern chipmunk at the entrance of its burrow A burrow is a hole or tunnel excavated into the ground by an animal to construct a space suitable for habitation or temporary refuge, or as a byproduct of locomotion. Burrows provide a form of sh ... scorpion, which often places its burrow beside a large rock. Compared to others of its genus, it has a particularly sturdy body with large pinchers. References External linksThe page of the ''Scorpionidae'' family at the Scorpion files Scorpionidae Scorpions of Africa Animals described in 1861 Taxa named by Wilhelm Peters {{Scorpion-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacillus Subtilis
''Bacillus subtilis'', known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants, humans and marine sponges. As a member of the genus ''Bacillus'', ''B. subtilis'' is rod-shaped, and can form a tough, protective endospore, allowing it to tolerate extreme environmental conditions. ''B. subtilis'' has historically been classified as an obligate aerobe, though evidence exists that it is a facultative anaerobe. ''B. subtilis'' is considered the best studied Gram-positive bacterium and a model organism to study bacterial chromosome replication and cell differentiation. It is one of the bacterial champions in secreted enzyme production and used on an industrial scale by biotechnology companies. Description ''Bacillus subtilis'' is a Gram-positive bacterium, rod-shaped and catalase-positive. It was originally named ''Vibrio subtilis'' by Christian Gottfried Ehrenberg, and renamed ''B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Klebsiella Pneumoniae
''Klebsiella pneumoniae'' is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium. It appears as a mucoid lactose fermenter on MacConkey agar. Although found in the normal flora of the mouth, skin, and intestines, it can cause destructive changes to human and animal lungs if aspirated, specifically to the alveoli resulting in bloody, brownish or yellow colored jelly like sputum. In the clinical setting, it is the most significant member of the genus ''Klebsiella'' of the Enterobacteriaceae. ''K. oxytoca'' and ''K. rhinoscleromatis'' have also been demonstrated in human clinical specimens. In recent years, ''Klebsiella'' species have become important pathogens in nosocomial infections. It naturally occurs in the soil, and about 30% of strains can fix nitrogen in anaerobic conditions. As a free-living diazotroph, its nitrogen-fixation system has been much-studied, and is of agricultural interest, as ''K. pneumoniae'' has been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudomonas Aeruginosa
''Pseudomonas aeruginosa'' is a common encapsulated, gram-negative, aerobic–facultatively anaerobic, rod-shaped bacterium that can cause disease in plants and animals, including humans. A species of considerable medical importance, ''P. aeruginosa'' is a multidrug resistant pathogen recognized for its ubiquity, its intrinsically advanced antibiotic resistance mechanisms, and its association with serious illnesses – hospital-acquired infections such as ventilator-associated pneumonia and various sepsis syndromes. The organism is considered opportunistic insofar as serious infection often occurs during existing diseases or conditions – most notably cystic fibrosis and traumatic burns. It generally affects the immunocompromised but can also infect the immunocompetent as in hot tub folliculitis. Treatment of ''P. aeruginosa'' infections can be difficult due to its natural resistance to antibiotics. When more advanced antibiotic drug regimens are needed adverse effects may re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peptides
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic peptides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
