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Hershel Jick
Hershel M. Jick (born December 1, 1931) is an American medical researcher and associate professor of medicine at Boston University School of Medicine, where he was formerly the director of the Boston Collaborative Drug Surveillance Program. Education Jick graduated from Harvard Medical School in 1956 and completed an internal medicine residency and clinical pharmacology fellowship. Career Jick is known for researching the negative and positive effects of pharmaceutical drugs. A 1977 study by him and his assistant Jane Porter reported that no more than one patient per 3,600 died because of incorrect drug prescriptions. The "Porter–Jick study" was mentioned in the Hulu miniseries ''Dopesick'' and Jick was portrayed by theatre actor Mark Jacoby. In 1980, Jick and Porter published the letter "Addiction Rare in Patients Treated with Narcotics", which has been cited to argue that opioid Opioids are substances that act on opioid receptors to produce morphine-like effects. Me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston University
Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campus in Newbury, Vermont, before moving to Boston in 1867. The university now has more than 4,000 faculty members and nearly 34,000 students, and is one of Boston's largest employers. It offers bachelor's degrees, master's degrees, doctorates, and medical, dental, business, and law degrees through 17 schools and colleges on three urban campuses. The main campus is situated along the Charles River in Boston's Fenway-Kenmore and Allston, Massachusetts, Allston neighborhoods, while the Boston University Medical Campus is located in Boston's South End, Boston, South End neighborhood. The Fenway campus houses the Wheelock College of Education and Human Development, formerly Wheelock College, which merged with BU in 2018. BU is a member of the Bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston University School Of Medicine
The Boston University Chobanian & Avedisian School of Medicine, formerly the Boston University School of Medicine, is one of the graduate schools of Boston University. Founded in 1848, the medical school was the first institution in the world to formally educate female physicians. Originally known as the New England Female Medical College, it was subsequently renamed Boston University School of Medicine in 1873, then Chobanian & Avedisian School of Medicine in 2022. In 1864, it became the first medical school in the United States to award an M.D. degree to an African-American woman. Chobanian & Avedisian School of Medicine is the only medical school located in the South End neighborhood of Boston, Massachusetts. Boston Medical Center, its primary teaching hospital, operates the largest 24-hour Level I trauma center in New England, and the largest network of regional community health centers. Chobanian & Avedisian School of Medicine is the home of the Framingham Heart Study, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hulu
Hulu () is an American subscription streaming service majority-owned by The Walt Disney Company, with Comcast's NBCUniversal holding a minority stake. It was launched on October 29, 2007 and it offers a library of films and television series like 20th Century Studios, Searchlight Pictures, Disney Television Studios, ABC, Freeform, and FX Networks among others, as well as Hulu original programming. Hulu was initially established as a joint venture between News Corporation and NBC Universal, Providence Equity Partners, and later The Walt Disney Company, serving as an aggregation of recent episodes of television series from their respective television networks. In 2010, Hulu launched a subscription service, initially branded as "Hulu Plus", which featured full seasons of programs from the companies and other partners, and undelayed access to new episodes. In 2017, the company launched ''Hulu with Live TV''—an over-the-top live TV service featuring linear television channel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dopesick (miniseries)
''Dopesick'' is an American drama miniseries, created by Danny Strong for Hulu. Based on the non-fiction book ''Dopesick: Dealers, Doctors, and the Drug Company that Addicted America'' by Beth Macy, it premiered on October 13, 2021, and concluded on November 17, 2021, after eight episodes. The series received mostly positive reviews from critics, with particular praise for the performances of the cast, most notably those of Kaitlyn Dever and Michael Keaton. At the 74th Primetime Emmy Awards, the series received fourteen nominations, including Outstanding Limited or Anthology Series and acting nominations for Keaton, Dever, Will Poulter, Peter Sarsgaard, Michael Stuhlbarg, and Mare Winningham, with Keaton winning for Outstanding Lead Actor in a Limited or Anthology Series or Movie. In addition, Keaton also won as Lead Actor at the 79th Golden Globe Awards, 28th Screen Actors Guild Awards and 12th Critics' Choice Television Awards. Premise ''Dopesick'' focuses on "the epicenter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mark Jacoby
Mark Jacoby (born May 21, 1947) is an American musical theatre performer. He has achieved fame from his leading roles on Broadway theatre, Broadway in ''Show Boat'', ''The Phantom of the Opera (1986 musical), The Phantom of the Opera'' and ''Ragtime (musical), Ragtime'', among others. He has also performed widely in national tours, regional theatre and Off-Broadway. Career On Broadway, Jacoby appeared in the revival of ''Sweet Charity'' from 1986 to 1987. He portrayed the Phantom in ''The Phantom of the Opera (1986 musical), The Phantom of the Opera'' from 1991 to 1993. Jacoby later appeared in the revivals of ''Grand Hotel (musical), Grand Hotel, Show Boat'', ''Man of La Mancha'', and ''Sweeney Todd (musical), Sweeney Todd.'' For his role in ''Show Boat'', he was nominated for a Tony Award in 1994. Jacoby acted in the original productions of ''Elf: The Musical'' and ''Ragtime (musical), Ragtime'' and portrayed Wizard of Oz (character), Wizard of Oz in the touring production of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Addiction Rare In Patients Treated With Narcotics
"Addiction Rare in Patients Treated with Narcotics" is the title of a letter to the editor written by Jane Porter and Hershel Jick and published in the January 10, 1980, issue of ''The New England Journal of Medicine''. The letter analyzed data on patients who had been treated with opioids in a hospital setting, and concluded that addiction was uncommon among such patients. It has since been frequently misrepresented to claim that opioids are not addictive when prescribed for use at home, which has been blamed for contributing to the opioid epidemic in the United States. Content The letter reported on an examination of medical files of patients who had been hospitalized and treated with small doses of opioids. The authors concluded that of the 11,882 patients who received at least one narcotic drug, only four of them had developed a "reasonably well documented" addiction among patients who had no history of addiction. Its text read, in its entirety: Influence The article was subseq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, and suppressing cough. Extremely potent opioids such as carfentanil are approved only for veterinary use. Opioids are also frequently used non-medically for their euphoric effects or to prevent withdrawal. Opioids can cause death and have been used for executions in the United States. Side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria. Long-term use can cause tolerance, meaning that increased doses are required to achieve the same effect, and physical dependence, meaning that abruptly discontinuing the drug leads to unpleasant withdrawal symptoms. The euphoria attracts recreational use, and frequent, escalating recreational use of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
