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Herschel K. Mitchell
Herschel Kenworthy Mitchell (November 27, 1913 – April 1, 2000) was an American professor of biochemistry who spent most of his career on the faculty at the California Institute of Technology. He was one of many researchers interested in vitamin B6 in the early 1940s and is credited as one of the discoverers of folic acid. He later focused his research on ''Drosophila'' (fruit flies), in particular the genetics and biochemistry of the heat shock response. Early life and education Mitchell was born on November 27, 1913, in Los Nietos, California. He received a bachelor's degree in chemistry from Pomona College in 1936, a master's degree from Oregon State College in 1938, and a Ph.D. from the University of Texas in 1941, where he worked with Roger J. Williams and Esmond Emerson Snell in their work on vitamin B6 and folic acid. He is recognized as a co-discoverer of folic acid, which the three scientists extracted from four tons of processed spinach. In 1943 Mitchell moved f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Los Nietos, California
West Whittier-Los Nietos () is a census-designated place (CDP) in Los Angeles County, California, near the San Gabriel River and the San Gabriel River (I-605) Freeway. The population was 25,540 at the 2010 census, up from 25,129 at the 2000 census. The census area consists of separate unincorporated communities of Los Nietos (Spanish for "the grandchildren") and West Whittier. Geography West Whittier-Los Nietos is located at (33.976113, -118.069000), or about three miles (5 km) northwest of Whittier. According to the United States Census Bureau, the CDP has a total area of , all land. Demographics 2010 At the 2010 census West Whittier-Los Nietos had a population of 25,540. The population density was . The racial makeup of West Whittier-Los Nietos was 15,170 (59.4%) White (9.3% Non-Hispanic White), 254 (1.0%) African American, 372 (1.5%) Native American, 393 (1.5%) Asian, 43 (0.2%) Pacific Islander, 8,404 (32.9%) from other races, and 904 (3.5%) from two or more races. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Beadle
George Wells Beadle (October 22, 1903 – June 9, 1989) was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells. He also served as the 7th President of the University of Chicago. Beadle and Tatum's key experiments involved exposing the bread mold ''Neurospora crassa'' to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways. These experiments led them to propose a direct link between genes and enzymatic reactions, known as the One gene-one enzyme hypothesis. Education and early life George Wells Beadle was born in Wahoo, Nebraska. He was the son of Chauncey Elmer Beadle and Hattie Albro, who owned and operated a farm nearby. George was educated at the Wahoo High School and might himself have become a farmer if one of his teachers a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1913 Births
Events January * January 5 – First Balkan War: Battle of Lemnos – Greek admiral Pavlos Kountouriotis forces the Turkish fleet to retreat to its base within the Dardanelles, from which it will not venture for the rest of the war. * January 13 – Edward Carson founds the (first) Ulster Volunteer Force, by unifying several existing loyalist militias to resist home rule for Ireland. * January 23 – 1913 Ottoman coup d'état: Ismail Enver comes to power. * January – Stalin (whose first article using this name is published this month) travels to Vienna to carry out research. Until he leaves on February 16 the city is home simultaneously to him, Hitler, Trotsky and Tito alongside Berg, Freud and Jung and Ludwig and Paul Wittgenstein. February * February 1 – New York City's Grand Central Terminal, having been rebuilt, reopens as the world's largest railroad station. * February 3 – The 16th Amendment to the United S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
California Institute Of Technology Faculty
The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasionally referred to as "CIT", most notably in its alma mater, but this is uncommon. is a private research university in Pasadena, California. Caltech is ranked among the best and most selective academic institutions in the world, and with an enrollment of approximately 2400 students (acceptance rate of only 5.7%), it is one of the world's most selective universities. The university is known for its strength in science and engineering, and is among a small group of institutes of technology in the United States which is primarily devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery Ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glassblower
Glassblowing is a glassforming technique that involves inflating molten glass into a bubble (or parison) with the aid of a blowpipe (or blow tube). A person who blows glass is called a ''glassblower'', ''glassmith'', or ''gaffer''. A '' lampworker'' (often also called a glassblower or glassworker) manipulates glass with the use of a torch on a smaller scale, such as in producing precision laboratory glassware out of borosilicate glass. Technology Principles As a novel glass forming technique created in the middle of the 1st century BC, glassblowing exploited a working property of glass that was previously unknown to glassworkers; inflation, which is the expansion of a molten blob of glass by introducing a small amount of air into it. That is based on the liquid structure of glass where the atoms are held together by strong chemical bonds in a disordered and random network,Frank, S 1982. Glass and Archaeology. Academic Press: London. Freestone, I. (1991). "Looking into Glass". ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Professor Emeritus
''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title the rank of the last office held". In some cases, the term is conferred automatically upon all persons who retire at a given rank, but in others, it remains a mark of distinguished service awarded selectively on retirement. It is also used when a person of distinction in a profession retires or hands over the position, enabling their former rank to be retained in their title, e.g., "professor emeritus". The term ''emeritus'' does not necessarily signify that a person has relinquished all the duties of their former position, and they may continue to exercise some of them. In the description of deceased professors emeritus listed at U.S. universities, the title ''emeritus'' is replaced by indicating the years of their appointmentsThe Protoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert P
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of ''Hrōþ, Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use Robert (surname), as a surname. Another commonly used form of the name is Rupert (name), Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta (given name), Roberta. The Italian, Portuguese, and Spanish form is Roberto (given name), Roberto. Robert is also a common name in many Germanic languages, including English ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metabolism
Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as ''catabolic'' – the ''breaking down'' of compounds (for example, of glucose to pyruvate by ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tryptophan Synthase
Tryptophan synthase or tryptophan synthetase is an enzyme () that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae. However, it is absent from Animalia. It is typically found as an α2β2 tetramer. The α subunits catalyze the reversible formation of indole and glyceraldehyde-3-phosphate (G3P) from indole-3-glycerol phosphate (IGP). The β subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Each α active site is connected to a β active site by a 25 angstrom long hydrophobic channel contained within the enzyme. This facilitates the diffusion of indole formed at α active sites directly to β active sites in a process known as substrate channeling. The active sites of tryptophan synthase are allosterically coupled. Enzyme structure Subunits: Tryptophan synthase typically exists as an α-ββ-α comple ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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