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Herbert Tabor
Herbert Tabor (November 28, 1918 – August 20, 2020) was an American biochemist and physician-scientist who specialized in the function of polyamines and their role in human health and disease. Tabor was a principal investigator at the National Institute of Diabetes and Digestive and Kidney Diseases where he was Chief of the Laboratory of Biochemical Pharmacology. He was the editor-in-chief of the ''Journal of Biological Chemistry'' from 1971 to 2010. Education Tabor was born in New York City in 1918. Tabor received a Bachelor of Arts at Harvard College in 1937 and a Doctor of Medicine at Harvard Medical School (HMS) in 1941. He was a researcher in the department of biological chemistry at HMS in 1941. Tabor worked in the lab of John Peters researching a carbon monoxide method to measure blood volumes while he completed a medical internship at Yale New Haven Hospital from 1942 to 1943. Career Tabor was a principal investigator at the National Institute of Diabetes and Diges ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City, New York
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biosynthesis
Biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides. Biosynthesis is usually synonymous with anabolism. The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Physicians
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman emperor, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Biochemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman emperor, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2020 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1918 Births
This year is noted for the end of the World War I, First World War, on the eleventh hour of the eleventh day of the eleventh month, as well as for the Spanish flu pandemic that killed 50–100 million people worldwide. Events Below, the events of World War I have the "WWI" prefix. January * January – 1918 flu pandemic: The "Spanish flu" (influenza) is first observed in Haskell County, Kansas. * January 4 – The Finnish Declaration of Independence is recognized by Russian Soviet Federative Socialist Republic, Soviet Russia, Sweden, German Empire, Germany and France. * January 9 – Battle of Bear Valley: U.S. troops engage Yaqui people, Yaqui Native American warriors in a minor skirmish in Arizona, and one of the last battles of the American Indian Wars between the United States and Native Americans. * January 15 ** The keel of is laid in Britain, the first purpose-designed aircraft carrier to be laid down. ** The Red Army (The Workers and Peasants Red Army) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston Streetcar
As with many large cities, a large number of Boston-area streetcar lines once existed, and many continued operating into the 1950s. However, only a few now remain, namely the four branches of the Green Line and the Ashmont–Mattapan High-Speed Line, with only one (the Green Line E branch) running regular service on an undivided street. History The first streetcar line in the Boston area was a horse-drawn line from Central Square, Cambridge to Bowdoin Square, Boston opened by the Cambridge Railroad on March 26, 1856. Over the following decade a large number of horsecar lines were built by different companies, including the Metropolitan Railroad, Middlesex Railroad, and South Boston Railroad; these companies competed with each other while also sharing tracks in many locations. By the mid-1860s horsecar lines reached to Lynn, Arlington, Watertown, Newton, West Roxbury, and Milton. In 1887 the various Boston-area horsecar companies (except for the Lynn and Boston Railroad) were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
S-adenosylmethionine Decarboxylase
The enzyme adenosylmethionine decarboxylase () catalyzes the conversion of S-Adenosyl methionine, ''S''-adenosyl methionine to S-Adenosylmethioninamine, ''S''-adenosylmethioninamine. Polyamines such as spermidine and spermine are essential for cell (biology), cellular cell growth, growth under most conditions, being implicated in many cellular processes including DNA, RNA and protein biosynthesis, protein synthesis. S-adenosylmethionine decarboxylase (AdoMetDC) plays an essential regulatory role in the polyamine biosynthetic pathway by generating the n-propylamine residue required for the synthesis of spermidine and spermine from putrescein. Unlike many amino acid decarboxylases AdoMetDC uses a covalently bound pyruvate residue as a Cofactor (biochemistry), cofactor rather than the more common pyridoxal 5'-phosphate. These proteins can be divided into two main groups which show little sequence (biology), sequence similarity either to each other, or to other pyruvoyl-dependent amin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spermine Synthase
Spermine synthase (, ''spermidine aminopropyltransferase'', ''spermine synthetase'') is an enzyme that converts spermidine into spermine. This enzyme catalyses the following chemical reaction : S-adenosylmethioninamine + spermidine \rightleftharpoons S-methyl-5'-thioadenosine + spermine Spermine synthase is an enzyme involved in polyamine biosynthesis. It is present in all eukaryotes and plays a role in a variety of biological functions in plants Its structure consists of two identical monomers of 41 kDa with three domains each, creating a homodimer formed via dimerization A dimer () (''wikt:di-, di-'', "two" + ''-mer'', "parts") is an oligomer consisting of two monomers joined by bonds that can be either strong or weak, Covalent bond, covalent or Intermolecular force, intermolecular. Dimers also have significant im .... The interactions between one of the three domains, the N-terminals of the monomers, is responsible for dimerization as that is where the active site is located; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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