Herbert E. Kaufman
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Herbert E. Kaufman
Herbert Edward Kaufman (September 28, 1931) is an American ophthalmologist who discovered idoxuridine, the first clinically useful antiviral agent; co-developed with William Bourne the clinical specular microscope to view the live corneal endothelium, co-developed timolol with Thomas Zimmerman, a new class of medications to treat glaucoma; corneal storage media for eye banks; natamycin, the first commercially available medication to treat fungal infections of the eye; co-developed with Tony Gasset the use of bandage contact lenses; and was involved in the first laser vision photorefractive keratectomy of the eye with Marguarite McDonald. Scientific career He began his Princeton University education at age 16, where he graduated Phi Beta Kappa and Magna Cum Laude with a degree in chemistry. This was followed by medical school at Harvard University. Kaufman Graduated in 1956 Magna Cum Laude and Alpha Omega Alpha. He received the New England Pathology Society Award for developing a n ...
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Brooklyn, New York
Brooklyn () is a borough of New York City, coextensive with Kings County, in the U.S. state of New York. Kings County is the most populous county in the State of New York, and the second-most densely populated county in the United States, behind New York County (Manhattan). Brooklyn is also New York City's most populous borough,2010 Gazetteer for New York State
. Retrieved September 18, 2016.
with 2,736,074 residents in 2020. Named after the Dutch village of Breukelen, Brooklyn is located on the w ...
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Thomas Zimmerman
Thomas Cadwallader Zimmerman (January 23, 1838 – November 13, 1914) was a Pennsylvania German writer and translator, notable for his translations of English language classics into the Pennsylvania German dialect. He was also the editor of the ''Reading Times'' newspaper in Reading, Berks County, Pennsylvania. Life and career Zimmerman was born in Lebanon County, Pennsylvania in the United States in 1838.Rosenberger, p. 507. There he attended public school until he was thirteen years old, and was apprenticed as a printer with the ''Lebanon Courier''.''Biography'', p. 89. Upon completion of his apprenticeship, he went to Philadelphia to work at ''The Philadelphia Inquirer''. In 1856, he became a journeyman printer with the ''Berks and Schuylkill Journal''. He relocated to Columbia, South Carolina in 1859, and returned to the Reading area at the outset of the American Civil War, where in 1863 he enlisted in Company C of the 42nd Regiment of Pennsylvania Volunteers.''Bi ...
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Massachusetts Eye And Ear Infirmary
Massachusetts Eye and Ear (Mass. Eye and Ear, or MEE) is a specialty hospital located in Boston, Massachusetts, United States, which focuses on ophthalmology (eye), otolaryngology (ear/nose/throat), and related medicine and research. Founded in 1824 as the Boston Eye Infirmary (BEI), it has also been known as the Massachusetts Charitable Eye and Ear Infirmary (MCEEI), and Massachusetts Eye and Ear Infirmary (MEEI). It is a teaching partner of Harvard Medical School. Massachusetts Eye and Ear has earned an international reputation for its successful treatment of the most difficult diseases and conditions of the eye, ear, nose, throat, head, and neck, and for its outstanding contributions to medical research and education. In 2018, Massachusetts Eye and Ear has two adult specialties nationally ranked the "U.S. News Best Hospitals Rankings and Ratings 2018-18, with the Department of Ophthalmology ranked number four in the U.S. and the Department of Otolaryngology placing number ...
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Ophthalmology
Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. This may include a one-year integrated internship that involves more general medical training in other fields such as internal medicine or general surgery. Following residency, additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care - medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many include research as part ...
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Pyrimethamine
Pyrimethamine, sold under the brand name Daraprim among others, is a medication used with leucovorin (leucovorin is used to decrease side effects of pyrimethamine; it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis. It is also used with dapsone as a second-line option to prevent ''Pneumocystis jiroveci'' pneumonia in people with HIV/AIDS. It was previously used for malaria but is no longer recommended due to resistance. Pyrimethamine is taken by mouth. Common side effects include gastrointestinal upset, severe allergic reactions, and bone marrow suppression. It should not be used by people with folate deficiency that has resulted in anemia. There is concern that it may increase the risk of cancer. While occasionally used in pregnancy it is unclear if pyrimethamine is safe for the baby. Pyrimethamine is classified as a folic acid antagonist. It works by inhibiting folic acid metabolism and therefore the maki ...
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Toxoplasma
''Toxoplasma gondii'' () is an obligate intracellular parasitic protozoan (specifically an apicomplexan) that causes toxoplasmosis. Found worldwide, ''T. gondii'' is capable of infecting virtually all warm-blooded animals, but felids, such as domestic cats, are the only known definitive hosts in which the parasite may undergo sexual reproduction. ''T. gondii'' has been shown to alter the behavior of infected rodents in ways that increase the rodents' chances of being preyed upon by felids. Support for this "manipulation hypothesis" stems from studies showing that ''T. gondii''-infected rats have a decreased aversion to cat urine. Because cats are the only hosts within which ''T. gondii'' can sexually reproduce to complete and begin its lifecycle, such behavioral manipulations are thought to be evolutionary adaptations that increase the parasite's reproductive success. Rats that do not avoid cat habitations will more likely become cat prey. ''Toxoplasma gondii'' infection i ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
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Alpha Omega Alpha
Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. Alpha Omega Alpha currently has active Chapters in 132 LCME- accredited medical schools in the United States and Lebanon. It annually elects over 4,000 new members. The majority of new members are elected in their final year of medical school, but distinguished teachers, faculty members, residents, and alumni can also be inducted into the society. All elections are held at local Chapters. No elections are held nationally. History ΑΩΑ was founded in 1902 by William Webster Root and five other medical students at the College of Physicians and Surgeons, which later became the University of Illinois College of Medicine. The impetus for its formation was the generally poor quality of American medical schools and students at the time; Root and his colleagues wished to promote excellence in these groups. They decided that membership in ΑΩΑ was to be based on both scholarly achievement and pro ...
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Phi Beta Kappa
The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, and to induct the most outstanding students of arts and sciences at only select American colleges and universities. It was founded at the College of William and Mary on December 5, 1776, as the first collegiate Greek-letter fraternity and was among the earliest collegiate fraternal societies. Since its inception, 17 U.S. Presidents, 40 U.S. Supreme Court Justices, and 136 Nobel Laureates have been inducted members. Phi Beta Kappa () stands for ('), which means "Wisdom it. love of knowledgeis the guide it. helmsmanof life". Membership Phi Beta Kappa has chapters in only about 10% of American higher learning institutions, and only about 10% of these schools' Arts and Sciences graduates are invited to join the society. ...
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Photorefractive Keratectomy
Photorefractive keratectomy (PRK) and laser-assisted sub-epithelial keratectomy (or laser epithelial keratomileusis) (LASEK) are laser eye surgery procedures intended to correct a person's vision, reducing dependency on glasses or contact lenses. LASEK and PRK permanently change the shape of the anterior central cornea using an excimer laser to ablate (remove by vaporization) a small amount of tissue from the corneal stroma at the front of the eye, just under the corneal epithelium. The outer layer of the cornea is removed prior to the ablation. A computer system tracks the patient's eye position 60 to 4,000 times per second, depending on the specifications of the laser that is used. The computer system redirects laser pulses for precise laser placement. Most modern lasers will automatically center on the patient's visual axis and will pause if the eye moves out of range and then resume ablating at that point after the patient's eye is re-centered. The outer layer of the cornea, ...
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Contact Lenses
Contact lenses, or simply contacts, are thin lenses placed directly on the surface of the eyes. Contact lenses are ocular prosthetic devices used by over 150 million people worldwide, and they can be worn to correct vision or for cosmetic or therapeutic reasons. In 2010, the worldwide market for contact lenses was estimated at $6.1 billion, while the US soft lens market was estimated at $2.1 billion.Nichols, Jason J., et a"ANNUAL REPORT: Contact Lenses 2010" January 2011. Multiple analysts estimated that the global market for contact lenses would reach $11.7 billion by 2015. , the average age of contact lens wearers globally was 31 years old, and two-thirds of wearers were female.Morgan, Philip B., et al"International Contact Lens Prescribing in 2010" ''Contact Lens Spectrum''. October 2011. People choose to wear contact lenses for many reasons. Aesthetics and cosmetics are main motivating factors for people who want to avoid wearing glasses or to change the appearance or c ...
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