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Henry Hallett Dale
Sir Henry Hallett Dale (9 June 1875 – 23 July 1968) was an English pharmacologist and physiologist. For his study of acetylcholine as agent in the chemical transmission of nerve pulses (neurotransmission) he shared the 1936 Nobel Prize in Physiology or Medicine with Otto Loewi. Early life and education Henry Hallett Dale was born in Islington, London, to Charles James Dale, a pottery manufacturer from Staffordshire, and his wife, Frances Anne Hallett, daughter of a furniture manufacturer, from South Devon.Feldberg W, rev. Tansey EM (2004–2011)Dale, Sir Henry Hallett (1875–1968) ''Oxford Dictionary of National Biography'', Oxford University Press, 2004; online edn, Jan 2011. Retrieved 2011-07-08. Henry was the third of seven children, one of whom (his younger brother, Benjamin Dale) became an accomplished composer and warden of the Royal Academy of Music. Henry was educated at the local Tollington Park College and then The Leys School Cambridge (one of the school's hous ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Islington
Islington () is a district in the north of Greater London, England, and part of the London Borough of Islington. It is a mainly residential district of Inner London, extending from Islington's High Street to Highbury Fields, encompassing the area around the busy High Street, Upper Street, Essex Road (former "Lower Street"), and Southgate Road to the east. Modern definition Islington grew as a sprawling Middlesex village along the line of the Great North Road, and has provided the name of the modern borough. This gave rise to some confusion, as neighbouring districts may also be said to be in Islington. This district is bounded by Liverpool Road to the west and City Road and Southgate Road to the south-east. Its northernmost point is in the area of Canonbury. The main north–south high street, Upper Street splits at Highbury Corner to Holloway Road to the west and St. Paul's Road to the east. The Angel business improvement district (BID), an area centered around the Angel t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cameron Prize For Therapeutics Of The University Of Edinburgh
The Cameron Prize for Therapeutics of the University of Edinburgh is awarded by the College of Medicine and Veterinary Medicine to a person who has made any highly important and valuable addition to Practical Therapeutics in the previous five years. The prize, which may be awarded biennially, was founded in 1878 by Dr Andrew Robertson Cameron of Richmond, New South Wales, with a sum of £2,000. The University's '' senatus academicus'' may require the prizewinner to deliver one or more lectures or to publish an account on the addition made to Practical Therapeutics. A list of recipients of the prize dates back to 1879. Cameron Prize winners See also * List of medicine awards This list of medicine awards is an index to articles about notable awards for contributions to medicine, the science and practice of establishing the diagnosis, prognosis, treatment, and prevention of disease. The list is organized by region and ... References {{reflist British lecture series Bri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotransmission
Neurotransmission (Latin: ''transmissio'' "passage, crossing" from ''transmittere'' "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away. A similar process occurs in retrograde neurotransmission, where the dendrites of the postsynaptic neuron release retrograde neurotransmitters (e.g., endocannabinoids; synthesized in response to a rise in intracellular calcium levels) that signal through receptors that are located on the axon terminal of the presynaptic neuron, mainly at GABAergic and glutamatergic synapses. Neurotransmission is regulated by several different factors: the availability and rate-of-synthesis of the neurotransmitter, the release of that neurotransmitter, the baseline activity of the postsynaptic cell, the number of available postsynapti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Synapse
Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body. At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are contained within small sacs called synaptic vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to neurotransmitter receptors on the postsynaptic cell. Finally, the neurotransmitters are cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetylcholine
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that increase or decrease the overall activity of the cholinergic system are called cholinergics and anticholinergics, respectively. Acetylcholine is the neurotransmitter used at the neuromuscular junction—in other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property means that drugs that affect cholinergic systems can have very dangerous effects ranging from paralysis to convulsions. Acetylcholine is also a neurotransmitter in the autonomic nervous system, both as an internal transmitter for the sympathetic nervous system and as the final product released by the parasymp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacologist
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biographical Memoirs Of Fellows Of The Royal Society
The ''Biographical Memoirs of Fellows of the Royal Society'' is an academic journal on the history of science published annually by the Royal Society. It publishes obituaries of Fellows of the Royal Society. It was established in 1932 as ''Obituary Notices of Fellows of the Royal Society'' and obtained its current title in 1955, with volume numbering restarting at 1. Prior to 1932, obituaries were published in the ''Proceedings of the Royal Society''. The memoirs are a significant historical record and most include a full bibliography of works by the subjects. The memoirs are often written by a scientist of the next generation, often one of the subject's own former students, or a close colleague. In many cases the author is also a Fellow. Notable biographies published in this journal include Albert Einstein, Alan Turing, Bertrand Russell, Claude Shannon, Clement Attlee, Ernst Mayr, and Erwin Schrödinger. Each year around 40 to 50 memoirs of deceased Fellows of the Royal Soci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Medal (Royal Society Of Arts)
The Albert Medal of the Royal Society of Arts (RSA) was instituted in 1864 as a memorial to Prince Albert, who had been President of the Society for 18 years. It was first awarded in 1864 for "distinguished merit in promoting Arts, Manufactures and Commerce". In presenting the Medal, the Society now looks to acknowledge individuals, organizations and groups that lead progress and create positive change within contemporary society in areas that are linked closely to the Society's broad agenda. Through the Albert Medal, the Society acknowledges the creativity and innovation of those that work to tackle some of the world's intractable problems. Each year, the RSA identifies issues by asking the Society's Fellowship to suggest problems and subjects linked to the Society's programme. These proposals are reviewed and recommendations made to the Trustees and Council, who are responsible for selecting one upon which the Fellowship will be asked to nominate worthy recipients. Full list ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Freedom Of The City
The Freedom of the City (or Borough in some parts of the UK) is an honour bestowed by a municipality upon a valued member of the community, or upon a visiting celebrity or dignitary. Arising from the medieval practice of granting respected citizens freedom from serfdom, the tradition still lives on in countries such as the United States, United Kingdom, Ireland, Australia, Canada, South Africa and New Zealand—although today the title of "freeman" confers no special privileges. The Freedom of the City can also be granted by municipal authorities to military units which have earned the city's trust; in this context, it is sometimes called the Freedom of Entry. This allows them the freedom to parade through the city, and is an affirmation of the bond between the regiment and the citizenry. The honour was sometimes accompanied by a "freedom box", a small gold box inscribed to record the occasion; these are not usual today. In some countries, such as the United States, esteemed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of Merit
The Order of Merit (french: link=no, Ordre du Mérite) is an order of merit for the Commonwealth realms, recognising distinguished service in the armed forces, science, art, literature, or for the promotion of culture. Established in 1902 by King Edward VII, admission into the order remains the personal gift of its Sovereign—currently Edward VII's great-great-grandson, Charles III—and is restricted to a maximum of 24 living recipients from the Commonwealth realms, plus a limited number of honorary members. While all members are awarded the right to use the post-nominal letters ''OM'' and wear the badge of the order, the Order of Merit's precedence among other honours differs between countries. History In around 1773, King George III considered establishing an order of knighthood to be called the "Order of Minerva" with membership restricted to 24 distinguished artists and authors. Knights would be entitled to the post-nominal letters ''KM'', and would wear a silver nine-po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of The British Empire
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established on 4 June 1917 by King George V and comprises five classes across both civil and military divisions, the most senior two of which make the recipient either a knight if male or dame if female. There is also the related British Empire Medal, whose recipients are affiliated with, but not members of, the order. Recommendations for appointments to the Order of the British Empire were originally made on the nomination of the United Kingdom, the self-governing Dominions of the Empire (later Commonwealth) and the Viceroy of India. Nominations continue today from Commonwealth countries that participate in recommending British honours. Most Commonwealth countries ceased recommendations for appointments to the Order of the British Empire when they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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