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Help Conquer Cancer
Help Conquer Cancer is a volunteer computing project that runs on the BOINC platform. It is a joint project of the Ontario Cancer Institute and the Hauptman-Woodward Medical Research Institute. It is also the first project under World Community Grid to run with a GPU counterpart. Project Purpose The goal is to enhance the efficiency of protein X-ray crystallography, which will enable researchers to determine the structure of many cancer-related proteins faster. This will lead to improving the understanding of the function of these proteins, and accelerate the development of new pharmaceutical drugs. See also * BOINC * List of volunteer computing projects * World Community Grid World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding ... References External links Help Conquer Cancer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Help Conquer Cancer
Help Conquer Cancer is a volunteer computing project that runs on the BOINC platform. It is a joint project of the Ontario Cancer Institute and the Hauptman-Woodward Medical Research Institute. It is also the first project under World Community Grid to run with a GPU counterpart. Project Purpose The goal is to enhance the efficiency of protein X-ray crystallography, which will enable researchers to determine the structure of many cancer-related proteins faster. This will lead to improving the understanding of the function of these proteins, and accelerate the development of new pharmaceutical drugs. See also * BOINC * List of volunteer computing projects * World Community Grid World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding ... References External links Help Conquer Cancer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Volunteer Computing
Volunteer computing is a type of distributed computing in which people donate their computers' unused resources to a research-oriented project, and sometimes in exchange for credit points. The fundamental idea behind it is that a modern desktop computer is sufficiently powerful to perform billions of operations a second, but for most users only between 10-15% of its capacity is used. Typical uses like basic word processing or web browsing leave the computer mostly idle. The practice of volunteer computing, which dates back to the mid-1990s, can potentially make substantial processing power available to researchers at minimal cost. Typically, a program running on a volunteer's computer periodically contacts a research application to request jobs and report results. A middleware system usually serves as an intermediary. History The first volunteer computing project was the Great Internet Mersenne Prime Search, which was started in January 1996. It was followed in 1997 by distribute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BOINC
The Berkeley Open Infrastructure for Network Computing (BOINC, pronounced – rhymes with "oink") is an open-source middleware system for volunteer computing (a type of distributed computing). Developed originally to support SETI@home, it became the platform for many other applications in areas as diverse as medicine, molecular biology, mathematics, linguistics, climatology, environmental science, and astrophysics, among others. The purpose of BOINC is to enable researchers to utilize processing resources of personal computers and other devices around the world. BOINC development began with a group based at the Space Sciences Laboratory (SSL) at the University of California, Berkeley, and led by David P. Anderson, who also led SETI@home. As a high-performance volunteer computing platform, BOINC brings together 34,236 active participants employing 136,341 active computers (hosts) worldwide, processing daily on average 20.164 PetaFLOPS (it would be the 21st largest processin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ontario Cancer Institute
The Ontario Cancer Institute (OCI) is the research division of Princess Margaret Cancer Centre, affiliated to the University Health Network of the University of Toronto Faculty of Medicine. As Canada's first dedicated cancer hospital, it opened officially and began to receive patients in 1958, although its research divisions had begun work a year earlier. Because, at that time, a stigma was associated with the word "cancer", the hospital was soon renamed the Princess Margaret Hospital, although the whole operation was called the Ontario Cancer Institute incorporating the Princess Margaret Hospital, or OCI/PMH. Clinicians usually preferred the hospital name, while the scientists used OCI. The original location of the OCI/PMH was at 500 Sherbourne Street in Toronto. In 1995, the whole operation moved to a new building at 610 University Avenue, and the new Princess Margaret Hospital became part of the University Health Network. The OCI continued as the research arm of the PMH, that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hauptman-Woodward Medical Research Institute
The Hauptman-Woodward Medical Research Institute (HWI) is an independent, not-for-profit, biomedical research facility located in the Buffalo Niagara Medical Campus. Its focus is on structural biology with a strong history in methods development and the application of X-ray crystallography in fundamental studies. Medical research HWI scientists work to find the fundamental causes of many diseases. For example, cancer is being attacked by identifying new classes of anti-tumor agents including new inhibitors for hormone-dependent breast tumors. Other projects include: *Finding new ways to fight opportunistic infections in AIDS patients *Combating inflammation in arthritis and cardiovascular disease *Preventing bronchial infections in cystic fibrosis patients HWI scientists use a methodology known as structural biology, which allows them to create 3D models of the molecules that build up cells. The investigation results provide many insights into how these molecular machines work, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X-ray Crystallography
X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles and intensities of these diffracted beams, a crystallographer can produce a three-dimensional picture of the density of electrons within the crystal. From this electron density, the mean positions of the atoms in the crystal can be determined, as well as their chemical bonds, their crystallographic disorder, and various other information. Since many materials can form crystals—such as salts, metals, minerals, semiconductors, as well as various inorganic, organic, and biological molecules—X-ray crystallography has been fundamental in the development of many scientific fields. In its first decades of use, this method determined the size of atoms, the lengths and types of chemical bonds, and the atomic-scale differences among various mat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Drug
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berkeley Open Infrastructure For Network Computing
The Berkeley Open Infrastructure for Network Computing (BOINC, pronounced – rhymes with "oink") is an open-source middleware system for volunteer computing (a type of distributed computing). Developed originally to support SETI@home, it became the platform for many other applications in areas as diverse as medicine, molecular biology, mathematics, linguistics, climatology, environmental science, and astrophysics, among others. The purpose of BOINC is to enable researchers to utilize processing resources of personal computers and other devices around the world. BOINC development began with a group based at the Space Sciences Laboratory (SSL) at the University of California, Berkeley, and led by David P. Anderson, who also led SETI@home. As a high-performance volunteer computing platform, BOINC brings together 34,236 active participants employing 136,341 active computers (hosts) worldwide, processing daily on average 20.164 PetaFLOPS (it would be the 21st largest processing c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Volunteer Computing Projects
This is a comprehensive list of volunteer computing projects; a type of distributed computing where volunteers donate computing time to specific causes. The donated computing power comes from idle CPUs and GPUs in personal computers, video game consoles and Android devices. Each project seeks to utilize the computing power of many internet connected devices to solve problems and perform tedious, repetitive research in a very cost effective manner. Active projects Completed projects See also * List of grid computing projects * List of citizen science projects * List of crowdsourcing projects * List of free and open-source Android applications This is a list of notable applications (''apps'') that run on the Android platform which meet guidelines for free software and open-source software. Advertisement blocking Web browsers Office Suites and synchronisation Co ... * List of Berkeley Open Infrastructure for Network Computing (BOINC) projects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Community Grid
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario. World Community Grid utilizes unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the human genome, the human microbiome, HIV, dengue, muscular dystrophy, cancer, influenza, Ebola, Zika virus, virtual screening, rice crop yields, clean energy, water ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
