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Haplogroup M (mtDNA)
Haplogroup M is a human mitochondrial DNA (mtDNA) haplogroup. An enormous haplogroup spanning all the continents, the macro-haplogroup M, like its sibling the macro-haplogroup N, is a descendant of the haplogroup L3. All mtDNA haplogroups considered native outside of Africa are descendants of either haplogroup M or its sibling haplogroup N. Haplogroup M is relatively young, having a younger most recent common ancestor date than some subclades of haplogroup N such as haplogroup R. Origins There is a debate concerning the geographical origins of Haplogroup M and its sibling haplogroup N. Both lineages are thought to have been the main surviving lineages involved in the out of Africa migration (or migrations) because all indigenous lineages found outside Africa belong to haplogroup M or haplogroup N. Scientists are unsure whether the mutations that define haplogroups M and N occurred in Africa before the exit from Africa or in Asia after the exit from Africa. Determining the origi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Mitochondrial DNA Haplogroup
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the mitochon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L3 (mtDNA)
Haplogroup L3 is a human mitochondrial DNA (mtDNA) haplogroup. The clade has played a pivotal role in the early dispersal of anatomically modern humans. It is strongly associated with the out-of-Africa migration of modern humans of about 70–50,000 years ago. It is inherited by all modern non-African populations, as well as by some populations in Africa. Origin Haplogroup L3 arose close to 70,000 years ago, near the time of the recent out-of-Africa event. This dispersal originated in East Africa and expanded to West Asia, and further to South and Southeast Asia in the course of a few millennia, and some research suggests that L3 participated in this migration out of Africa. A 2007 estimate for the age of L3 suggested a range of 104–84,000 years ago. More recent analyses, including Soares et al. (2012) arrive at a more recent date, of roughly 70–60,000 years ago. Soares et al. also suggest that L3 most likely expanded from East Africa into Eurasia sometime around 65–55, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L2 (mtDNA)
Haplogroup L2 is a human mitochondrial DNA (mtDNA) haplogroup with a widespread modern distribution, particularly in Sub equatorial Africa. Its L2a subclade is a somewhat frequent and widely distributed mtDNA cluster on the continent, as well as among African Americans, The highest frequency occurs among the Mbuti Pygmies (64%). Origin L2 is a common lineage in Africa. It is believed to have evolved between 87,000 and 107,000 years ago or approx. 90,000 YBP. Its age and widespread distribution and diversity across the continent makes its exact origin point within Africa difficult to trace with any confidence. L2 Haplotypes is commonly observed in Central & South Eastern African populations, finding shared genetic matches with Southeast Africa and Central Africa. An origin for L2b, L2c, L2d and L2e in Southeastern Africa seems likely. The early diversity of L2 can be observed all over the African Continent, but as we can see in Subclades section below, the highest diversity is fou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toomas Kivisild
Toomas Kivisild (born 11 August 1969, in Tapa, Estonia) is an Estonian population geneticist. He graduated as a biologist and received his PhD in Genetics, from University of Tartu, Estonia, in 2000. Since then he has worked as a postdoctoral research fellow in the School of Medicine, at Stanford University (2002-3), Estonian Biocentre (since 2003), as the Professor of Evolutionary Biology, University of Tartu (2005-6), and as a Lecturer and Reader in Human Evolutionary Genetics in the Department of Archaeology and Anthropology at the University of Cambridge (2006-2018). From 2018 he is a professor in the Department of Human Genetics at KU Leuven KU Leuven (or Katholieke Universiteit Leuven) is a Catholic research university in the city of Leuven, Belgium. It conducts teaching, research, and services in computer science, engineering, natural sciences, theology, humanities, medicine, ... and a senior researcher at the Institute of Genomics, University of Tartu. Kivisild ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Admixture
Genetic admixture occurs when previously diverged or isolated genetic lineages mix.⅝ Admixture results in the introduction of new genetic lineages into a population. Examples Climatic cycles facilitate genetic admixture in cold periods and genetic diversification in warm periods. Natural flooding can cause genetic admixture within populations of migrating fish species. Genetic admixture may have an important role for the success of populations that colonise a new area and interbreed with individuals of native populations. Mapping Admixture mapping is a method of gene mapping that uses a population of mixed ancestry (an admixed population) to find the genetic loci that contribute to differences in diseases or other phenotypes found between the different ancestral populations. The method is best applied to populations with recent admixture from two populations that were previously genetically isolated. The method attempts to correlate the degree of ancestry near a genetic locus w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eurasian
Eurasia (, ) is the largest continental area on Earth, comprising all of Europe and Asia. Primarily in the Northern and Eastern Hemispheres, it spans from the British Isles and the Iberian Peninsula in the west to the Japanese archipelago and the Russian Far East to the east. The continental landmass is bordered by the Atlantic Ocean and Africa to the west, the Pacific Ocean to the east, the Arctic Ocean to the north, and by Africa, the Mediterranean Sea, and the Indian Ocean to the south. The division between Europe and Asia as two continents is a historical social construct, as many of their borders are over land; thus, in some parts of the world, Eurasia is recognized as the largest of the six, five, or four continents on Earth. In geology, Eurasia is often considered as a single rigid megablock. However, the rigidity of Eurasia is debated based on paleomagnetic data. Eurasia covers around , or around 36.2% of the Earth's total land area. It is also home to the largest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup U (mtDNA)
Haplogroup U is a human mitochondrial DNA haplogroup (mtDNA). The clade arose from haplogroup R, likely during the early Upper Paleolithic. Its various subclades (labelled U1–U9, diverging over the course of the Upper Paleolithic) are found widely distributed across Northern and Eastern Europe, Central, Western and South Asia, as well as North Africa, the Horn of Africa, and the Canary Islands. Origins Haplogroup U descends from the haplogroup R mtDNA branch of the phylogenetic tree. The defining mutations (A11467G, A12308G, G12372A) are estimated to have arisen between 43,000 and 50,000 years ago, in the early Upper Paleolithic (around 46,530 ± 3,290 years before present, with a 95% confidence interval per Behar et al., 2012). Ancient DNA classified as belonging to the U* mitochondrial haplogroup has been recovered from human skeletal remains found in Western Siberia, which have been dated to c. 45,000 years ago. The mitogenome (33-fold coverage) of the Peştera Mui ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tibet
Tibet (; ''Böd''; ) is a region in East Asia, covering much of the Tibetan Plateau and spanning about . It is the traditional homeland of the Tibetan people. Also resident on the plateau are some other ethnic groups such as Monpa people, Monpa, Tamang people, Tamang, Qiang people, Qiang, Sherpa people, Sherpa and Lhoba peoples and now also considerable numbers of Han Chinese and Hui people, Hui settlers. Since Annexation of Tibet by the People's Republic of China, 1951, the entire plateau has been under the administration of the People's Republic of China, a major portion in the Tibet Autonomous Region, and other portions in the Qinghai and Sichuan provinces. Tibet is the highest region on Earth, with an average elevation of . Located in the Himalayas, the highest elevation in Tibet is Mount Everest, Earth's highest mountain, rising 8,848.86 m (29,032 ft) above sea level. The Tibetan Empire emerged in the 7th century. At its height in the 9th century, the Tibet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Asia
Central Asia, also known as Middle Asia, is a subregion, region of Asia that stretches from the Caspian Sea in the west to western China and Mongolia in the east, and from Afghanistan and Iran in the south to Russia in the north. It includes the former Soviet Union, Soviet republics of the Soviet Union, republics of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan, which are colloquially referred to as the "-stans" as the countries all have names ending with the Persian language, Persian suffix "-stan", meaning "land of". The current geographical location of Central Asia was formerly part of the historic region of Turkestan, Turkistan, also known as Turan. In the pre-Islamic and early Islamic eras ( and earlier) Central Asia was inhabited predominantly by Iranian peoples, populated by Eastern Iranian languages, Eastern Iranian-speaking Bactrians, Sogdians, Khwarezmian language, Chorasmians and the semi-nomadic Scythians and Dahae. After expansion by Turkic peop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caucasus
The Caucasus () or Caucasia (), is a region between the Black Sea and the Caspian Sea, mainly comprising Armenia, Azerbaijan, Georgia, and parts of Southern Russia. The Caucasus Mountains, including the Greater Caucasus range, have historically been considered as a natural barrier between Eastern Europe and Western Asia. Mount Elbrus in Russia, Europe's highest mountain, is situated in the Western Caucasus. On the southern side, the Lesser Caucasus includes the Javakheti Plateau and the Armenian highlands, part of which is in Turkey. The Caucasus is divided into the North Caucasus and South Caucasus, although the Western Caucasus also exists as a distinct geographic space within the North Caucasus. The Greater Caucasus mountain range in the north is mostly shared by Russia and Georgia as well as the northernmost parts of Azerbaijan. The Lesser Caucasus mountain range in the south is occupied by several independent states, mostly by Armenia, Azerbaijan, and Georgia, but also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iran
Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkmenistan to the north, by Afghanistan and Pakistan to the east, and by the Gulf of Oman and the Persian Gulf to the south. It covers an area of , making it the 17th-largest country. Iran has a population of 86 million, making it the 17th-most populous country in the world, and the second-largest in the Middle East. Its largest cities, in descending order, are the capital Tehran, Mashhad, Isfahan, Karaj, Shiraz, and Tabriz. The country is home to one of the world's oldest civilizations, beginning with the formation of the Elamite kingdoms in the fourth millennium BC. It was first unified by the Medes, an ancient Iranian people, in the seventh century BC, and reached its territorial height in the sixth century BC, when Cyrus the Great fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Levant
The Levant () is an approximate historical geographical term referring to a large area in the Eastern Mediterranean region of Western Asia. In its narrowest sense, which is in use today in archaeology and other cultural contexts, it is equivalent to a stretch of land bordering the Mediterranean in South-western Asia,Gasiorowski, Mark (2016). ''The Government and Politics of the Middle East and North Africa''. }, ), meaning "the eastern place, where the Sun rises". In the 13th and 14th centuries, the term ''levante'' was used for Italian maritime commerce in the Eastern Mediterranean, including Greece, Anatolia, Syria-Palestine, and Egypt, that is, the lands east of Venice. Eventually the term was restricted to the Muslim countries of Syria-Palestine and Egypt. In 1581, England set up the Levant Company to monopolize commerce with the Ottoman Empire. The name ''Levant States'' was used to refer to the French mandate over Syria and Lebanon after World War I. This is probab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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