HARVEY (software)
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HARVEY (software)
Amanda Randles is an American computer scientist who is the Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences at Duke University. Randles is an associate professor of biomedical engineering with secondary appointments in computer science, mathematics, and mechanical engineering and materials science. She is a member of the Duke Cancer Institute. Her research interests include biomedical simulation, machine learning, computational fluid dynamics, and high-performance computing. Early career and education In high school, Randles attended the Utica Center for Math, Science, and Technology, where she learned computer programming and its applications in the sciences. She also participated in Science Olympiad and FIRST Robotics Competition, FIRST Robotics. Randles attended Duke University, where she completed a B.A. in physics and computer science in 2005. After working for three years as a software developer on the IBM Blue Gene project, she went ...
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Duke University
Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke. The campus spans over on three contiguous sub-campuses in Durham, and a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at the University of Pennsylvania School of Design—incorporates Gothic architecture with the Duke Chapel at the campus' center and highest point of elevation, is adjacent to the Medical Center. East Campus, away, home to all first-years, contains Georgian-style architecture. The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (established in ...
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Computational Science Graduate Fellowship
The Computational Science Graduate Fellowship (CSGF) program is a highly selective graduate fellowship program sponsored by the United States Department of Energy and administered by the Krell Institute. Started in 1990, it awards four-year fellowships for American graduate students pursuing graduate degrees in all areas of computational science. The award pays full tuition and an annual stipend of $45,000. Notable recipients *Kristen Grauman Kristen Lorraine Grauman is a Professor of Computer Science at the University of Texas at Austin on leave as a research scientist at Facebook AI Research (FAIR). She works on computer vision and machine learning. Early life and education Grau ... See also * Hertz Fellowship * NDSEG Fellowship * NSF Graduate Research Fellowship References Krell Institute Department of Energy Computational Science Graduate Fellowship website Fellowships {{US-edu-stub ...
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Summit (supercomputer)
Summit or OLCF-4 is a supercomputer developed by IBM for use at Oak Ridge Leadership Computing Facility (OLCF), a facility at the Oak Ridge National Laboratory, capable of 200 petaFLOPS thus making it the 4th fastest supercomputer in the world after Frontier (OLCF-5), Fugaku, and LUMI. It held the number 1 position from November 2018 to June 2020. Its current LINPACK benchmark is clocked at 148.6 petaFLOPS. As of November 2019, the supercomputer had ranked as the 5th most energy efficient in the world with a measured power efficiency of 14.668 gigaFLOPS/watt. Summit was the first supercomputer to reach exaflop (a quintillion operations per second) speed, achieving 1.88 exaflops during a genomic analysis and is expected to reach 3.3 exaflops using mixed-precision calculations. History The United States Department of Energy awarded a $325 million contract in November 2014 to IBM, NVIDIA and Mellanox. The effort resulted in construction of Summit and Sierra. Summit is ta ...
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Circulatory System
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek ''kardia'' meaning ''heart'', and from Latin ''vascula'' meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with the ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The Closed circulatory system, circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Some in ...
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Cardiovascular Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximat ...
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William Harvey
William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions in anatomy and physiology. He was the first known physician to describe completely, and in detail, the systemic circulation and properties of blood being pumped to the brain and the rest of the body by the heart, though earlier writers, such as Realdo Colombo, Michael Servetus, and Jacques Dubois, had provided precursors of the theory. Family William's father, Thomas Harvey, was a jurat of Folkestone where he served as mayor in 1600. Records and personal descriptions delineate him as an overall calm, diligent, and intelligent man whose "sons... revered, consulted and implicitly trusted in him... (they) made their father the treasurer of their wealth when they acquired great estates...(He) kept, employed, and improved their gainings to their great advantage." Thomas Harvey's portrait can still be seen in the central panel of a wall of the dining room at Rolls Park, Chig ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and oth ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ...
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Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheroma, atheromatous plaque. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which Artery, arteries are affected. The exact cause is not known and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory markers, high blood pressure, diabetes, smoking, obesity, family history, genetic, and an unhealthy diet. Atheroma, Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. The narrowing of Artery, arteries limits the flow of oxygen-rich blood to parts of the body. Diagnosis is based upon a physical exam, ele ...
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Dana–Farber Cancer Institute
Dana–Farber Cancer Institute is a comprehensive cancer treatment and research institution in Boston, Massachusetts. Dana–Farber is the founding member of Dana–Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated by the National Cancer Institute, and one of the 15 clinical affiliates and research institutes of Harvard Medical School. As of 2021, Dana–Farber is ranked the #3 cancer hospital in the world. Two Nobel laureates in Physiology or Medicine are among its past and present faculty. Dana–Farber's research discoveries include the development of the highly successful Gleevec to treat chronic myeloid leukemia. Overview Dana–Farber employs more than 4,855 full-time and part-time people, 529 faculty, and has annual gross revenues of about $1,733,386,000. All faculty and postdoctoral research fellows at Dana–Farber hold the equivalent academic positions concurrently at Harvard University. There are more than 523,425 adult and pediatric patie ...
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Franziska Michor
Franziska Michor (born 1982) is an Austrian-American computational biologist who is a Professor in the Department of Data Science at the Dana–Farber Cancer Institute. She serves as Director of the Physical Sciences-Oncology Center and the Center for Cancer Evolution. Education and early career Michor was born in Vienna. Her father was a mathematician and her mother was a nurse. As a child she became interested in mathematics, and inspire to follow a scientific career that helped others. Michor was an undergraduate student in mathematics and molecular biology at the University of Vienna. During her degree she spent a year at the University of Trieste, where she studied medical biotechnology. She moved to the Institute for Advanced Study as a graduate student, where she worked in theoretical biology. Michor was a doctoral researcher in Harvard University, where she was based in the Department of Organismic and Evolutionary Biology. Her thesis considered the evolutionary dynamics ...
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