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Hyraceum
Hyraceum () is the petrified and rock-like excrement composed of both urine and feces excreted by the Cape hyrax (''Procavia capensis'', also referred to as the rock hyrax or dassie). The rock hyrax defecates in the same location over generations, which may be sheltered in caves. These locations form middens that are composed of hyraceum and hyrax pellets, which can be petrified and preserved for over 50,000 years. These middens form a record of past climate and vegetation. It is also a sought-after material that has been used in both traditional South African medicine and perfumery. Hyraceum in perfumery The material hardens and ages until it becomes a fairly sterile, rock-like material (also referred to as "Africa Stone") that contains compounds giving it an animalic, deeply complex fermented scent that combines the elements of musk, castoreum, civet, tobacco and agarwood. The material is harvested without disturbing the animals by digging strata of the brittle, resinous, ir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rock Hyrax
The rock hyrax (; ''Procavia capensis''), also called dassie, Cape hyrax, rock rabbit, and (in the King James Bible) coney, is a medium-sized terrestrial mammal native to Africa and the Middle East. Commonly referred to in South Africa as the dassie (; af, klipdassie), it is one of the five living species of the order Hyracoidea, and the only one in the genus ''Procavia''. Rock hyraxes weigh and have short ears and tails. Rock hyraxes are found at elevations up to above sea level in habitats with rock crevices, allowing them to escape from predators. They are the only extant terrestrial afrotherians in the Middle East. Hyraxes typically live in groups of 10–80 animals, and forage as a group. They have been reported to use sentries to warn of the approach of predators. Having incomplete thermoregulation, they are most active in the morning and evening, although their activity pattern varies substantially with season and climate. Over most of its range, the rock hyrax is not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perfume Ingredients
Perfume (, ; french: parfum) is a mixture of fragrant essential oils or aroma compounds (fragrances), fixatives and solvents, usually in liquid form, used to give the human body, animals, food, objects, and living-spaces an agreeable scent. The 1939 Nobel Laureate for Chemistry, Leopold Ružička stated in 1945 that "right from the earliest days of scientific chemistry up to the present time, perfumes have substantially contributed to the development of organic chemistry as regards methods, systematic classification, and theory." Ancient texts and archaeological excavations show the use of perfumes in some of the earliest human civilizations. Modern perfumery began in the late 19th century with the commercial synthesis of aroma compounds such as vanillin or coumarin, which allowed for the composition of perfumes with smells previously unattainable solely from natural aromatics. History The word ''perfume'' derives from the Latin ''perfumare'', meaning "to smoke through" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Castoreum
Castoreum is a yellowish exudate from the castor sacs of mature beavers. Beavers use castoreum in combination with urine to scent mark their territory. Both beaver sexes have a pair of castor sacs and a pair of anal glands, located in two cavities under the skin between the pelvis and the base of the tail. The castor sacs are not true glands ( endocrine or exocrine) on a cellular level, hence references to these structures as preputial glands, castor glands, or scent glands are misnomers. It is used as a tincture in some perfumesInternational Perfume Museum, Grasse, France, Website: and was sometimes used as a food additive in the early 1900s. The sacs brought per ounce when auctioned at the May–June 2016 North American Fur Auction. Chemical composition At least 24 compounds are known constituents of beaver castoreum. Several of these have pheromonal activity, of which the phenols 4-ethylphenol and catechol and the ketones acetophenone and 3-hydroxyacetophenone were s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tinnunculite
Tinnunculite is a naturally-occurring form of dihydrate of uric acid. It should not be confused with a proposed mineral species with the identical name 'Tinnunculite', that forms when droppings from a European kestrel react with the burning dumps of coal mines and quarries. The name tinnunculite is derived from the kestrel's binomial name, "''Falco tinnunculus''", which is itself derived from the Latin word ''tinnunculus'', meaning "kestrel", from ''tinnulus'', meaning "shrill". Tinnunculite is a naturally occurring form of the same type of origin. The mineral is a dihydrate of uricite to which it is visually very similar. Tinnunculite is chemically similar to other organic minerals: guanine, uricite; also acetamide, kladnoite. A new mineral proposal with the same name but slightly different formula (C10H12N8O8) was submitted by Chesnokov & Shcherbakova and ultimately rejected by the International Mineralogical Association (IMA) on the basis of being of anthropogenic origin. Loc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, injected into a vein or used as a nasal spray. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects begin after 15 to 60 minutes. Common side-effects include sleepiness and trouble with coordination. Serious side effects are rare. They include increased risk of suicide, decreased breathing, and an increased risk of seizures if used too frequently in those with epilepsy. Occasionally, excitement or agitation may occur. Long-term use can result in tolerance, dependence, and withdrawal symptoms on dose reduction ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyraxes
Hyraxes (), also called dassies, are small, thickset, herbivorous mammals in the order Hyracoidea. Hyraxes are well-furred, rotund animals with short tails. Typically, they measure between long and weigh between . They are superficially similar to pikas and marmots, but are more closely related to elephants and sea cows. Hyraxes have a life span from 9 to 14 years. Five extant species are recognised: the rock hyrax (''Procavia capensis'') and the yellow-spotted rock hyrax (''Heterohyrax brucei''), which both live on rock outcrops, including cliffs in Ethiopia and isolated granite outcrops called koppies in southern Africa; the western tree hyrax (''Dendrohyrax dorsalis''), southern tree hyrax (''D. arboreus''), and eastern tree hyrax (''D. validus''). Their distribution is limited to Africa, except for ''P. capensis'', which is also found in the Middle East. Characteristics Hyraxes retain or have redeveloped a number of primitive mammalian characteristics; in particular, they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Animal Waste Products
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echinoderms an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lorazepam
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. It is also used during surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It can be given by mouth or as an injection into a muscle or vein. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day. Common side effects include weakness, sleepiness, low blood pressure, and a decreased effort to breathe. When given intravenously the person should be closely monitored. Among those who are depressed there may be an increased risk of suicide. With long-term use, larger doses may be required for the same ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzodiazepine Receptor
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Its endogenous ligand is γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Upon opening, the GABAA receptor on the postsynaptic cell is selectively permeable to chloride ions (Cl−) and, to a lesser extent, bicarbonate ions (HCO3−). Depending on the membrane potential and the ionic concentration difference, this can result in ionic fluxes across the pore. If the membrane potential is higher than the equilibrium potential (also known as the reversal potential) for chloride ions, when the receptor is activated Cl− will flow into the cell. This causes an inhibitory effect on neurotransmission by diminishing the chance of a successful action potential occurring at the postsynaptic cell. The reversal potential of the GABAA-mediated inhibitory postsynaptic potential (IPSP) in normal solution is −70 mV, contrasting the GABAB IPSP (-100 mV). Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzodiazapines
Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant, depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955 and was made available in 1960 by Hoffmann–La Roche, who soon followed with diazepam (Valium) in 1963. By 1977, benzodiazepines were the most prescribed medications globally; the introduction of selective serotonin reuptake inhibitors (SSRIs), among other factors, decreased rates of prescription, but they remain frequently used worldwide. Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-Aminobutyric acid, gamma-aminobutyric acid (GABA) at the GABAA receptor, GABAA receptor, resulting in sedative, hypnotic (Sleep induction, sleep-inducing), anxiolytic (anti-anxie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Musk
Musk (Persian: مشک, ''Mushk'') is a class of aromatic substances commonly used as base notes in perfumery. They include glandular secretions from animals such as the musk deer, numerous plants emitting similar fragrances, and artificial substances with similar odors. ''Musk'' was a name originally given to a substance with a strong odor obtained from a gland of the musk deer. The substance has been used as a popular perfume fixative since ancient times and is one of the most expensive animal products in the world. The name originates from the Late Greek μόσχος 'moskhos', from Persian 'mushk', similar to Sanskrit मुष्क muṣka ("testicle"), derived from Proto-Indo-European noun ''múh₂s'' meaning "mouse". The deer gland was thought to resemble a scrotum. It is applied to various plants and animals of similar smell (e.g. muskox) and has come to encompass a wide variety of aromatic substances with similar odors, despite their often differing chemical structure ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Traditional Medicine
Traditional medicine (also known as indigenous medicine or folk medicine) comprises medical aspects of traditional knowledge that developed over generations within the folk beliefs of various societies, including indigenous peoples, before the era of modern medicine. The World Health Organization (WHO) defines traditional medicine as "the sum total of the knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness". Traditional medicine is often contrasted with scientific medicine. In some Asian and African countries, up to 80% of the population relies on traditional medicine for their primary health care needs. When adopted outside its traditional culture, traditional medicine is often considered a form of alternative medicine. Practices known as traditional medicines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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