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Hypertrophic Osteodystrophy
Hypertrophic Osteodystrophy (HOD) is a bone disease that occurs most often in fast-growing large and giant breed dogs; however, it also affects medium breed animals like the Australian Shepherd. The disorder is sometimes referred to as ''metaphyseal osteopathy'', and typically first presents between the ages of 2 and 7 months. HOD is characterized by decreased blood flow to the metaphysis (the part of the bone adjacent to the joint) leading to a failure of ossification (bone formation) and necrosis and inflammation of cancellous bone. The disease is usually bilateral in the limb bones, especially the anatomical terms of location, distal radius (bone), radius, ulna, and tibia. The Weimaraner, Irish Setter, Boxer, German Shepherd, and Great Dane breeds are heavily represented in case reports of HOD in the veterinary literature, but the severity of symptoms and possible etiology may be different across the breeds. For example, familial clustering of the disease has been documented i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ossification
Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts. It is synonymous with bone tissue formation. There are two processes resulting in the formation of normal, healthy bone tissue: Intramembranous ossification is the direct laying down of bone into the primitive connective tissue ( mesenchyme), while endochondral ossification involves cartilage as a precursor. In fracture healing, endochondral osteogenesis is the most commonly occurring process, for example in fractures of long bones treated by plaster of Paris, whereas fractures treated by open reduction and internal fixation with metal plates, screws, pins, rods and nails may heal by intramembranous osteogenesis. Heterotopic ossification is a process resulting in the formation of bone tissue that is often atypical, at an extraskeletal location. Calcification is often confused with ossification. Calcification is sy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microfracture
Fracture mechanics is the field of mechanics concerned with the study of the propagation of cracks in materials. It uses methods of analytical solid mechanics to calculate the driving force on a crack and those of experimental solid mechanics to characterize the material's resistance to fracture. Theoretically, the stress ahead of a sharp crack tip becomes infinite and cannot be used to describe the state around a crack. Fracture mechanics is used to characterise the loads on a crack, typically using a single parameter to describe the complete loading state at the crack tip. A number of different parameters have been developed. When the plastic zone at the tip of the crack is small relative to the crack length the stress state at the crack tip is the result of elastic forces within the material and is termed linear elastic fracture mechanics (LEFM) and can be characterised using the stress intensity factor K. Although the load on a crack can be arbitrary, in 1957 G. Irwin found ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irish Setter
The Irish Setter ( ga, sotar rua, literally "red setter") is a setter, a breed of gundog, and family dog. The term ''Irish Setter'' is commonly used to encompass the show-bred dog recognised by the American Kennel Club as well as the field-bred Red Setter recognised by the Field Dog Stud Book. Description Appearance The coat is moderately long, silky, and of a red or chestnut colour. It requires frequent brushing to maintain its condition and keep it mat-free. The undercoat is abundant in winter weather, and the top coat is fine. Their coats should also feather in places such as the tail, ears, chest, legs, and body. Irish Setters range in height from , males weigh and females . The FCI Breed Standard for the Irish Setter stipulates males stand tall, and females be tall. Irish Setters are deep chested dogs with small waists. An Irish Setter's life expectancy tends to be around 11 to 12 years. Temperament Irish Setters get along well with children and other dogs and w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Dane
The Great Dane is a large sized dog breed originating from Germany. The Great Dane descends from hunting dogs from the Middle Ages used to hunt wild boar and deer, and as guardians of German nobility. It is one of the largest breeds in the world along with its relative, the Irish Wolfhound. History Origins In the middle of the 16th century, the nobility in many countries of Europe imported strong, long-legged dogs from England, which were descended from crossbreeds between English Mastiffs and Irish Wolfhounds. They were dog hybrids in different sizes and phenotypes with no formal breed.Ludwig Beckmann (1895)''Geschichte und Beschreibung der Rassen des Hundes'' Volume 1, p. 6 (in German) These dogs were called ''Englische Docke'' or ''Englische Tocke'' – later written and spelled: ''Dogge'' – or ''Englischer Hund'' in Germany. The name simply meant "English dog". Since then, the English word "dog" has come to be associated with a molossoid dog in Germany and France. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Golden Retriever
The Golden Retriever is a Scottish breed of retriever dog of medium size. It is characterised by a gentle and affectionate nature and a striking golden coat. It is commonly kept as a pet and is among the most frequently registered breeds in several Western countries. It is a frequent competitor in dog shows and obedience trials; it is also used as a gundog, and may be trained for use as a guide dog. The breed was created by Sir Dudley Marjoribanks at his Scottish estate Guisachan in the late nineteenth century. He cross-bred Flat-coated Retrievers with Tweed Water Spaniels, with some further infusions of Red Setter, Labrador Retriever and Bloodhound. The breed was recognised by the Kennel Club in 1913, and during the interwar period spread to many parts of the world. History The Golden Retriever was developed in Scotland in the nineteenth century by Sir Dudley Marjoribanks (later to become Baron Tweedmouth) from Flat-coated Retrievers judiciously crossed with Twe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Shepherd Dog
The German Shepherd or Alsatian is a German breed of working dog of medium to large size. The breed was developed by Max von Stephanitz using various traditional German herding dogs from 1899. It was originally bred as a herding dog, for herding sheep. It has since been used in many other types of work, including disability assistance, search-and-rescue, police work, and warfare. It is commonly kept as a companion dog, and according to the Fédération Cynologique Internationale had the second-highest number of annual registrations in 2013. History During the 1890s, attempts were being made to standardise dog breeds. Dogs were being bred to preserve traits that assisted in their job of herding sheep and protecting their flocks from predators. In Germany this was practised within local communities, where shepherds selected and bred dogs. It was recognised that the breed had the necessary skills for herding sheep, such as intelligence, speed, strength and keen senses o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dalmatian (dog)
The Dalmatian is a breed of dog, which has a white coat marked with black or brown-colored spots. Originating as a hunting dog, it was also used as a carriage dog in its early days. The origins of this breed can be traced back to present-day Croatia and its historical region of Dalmatia. It is thought that early ancestors of the breed were certain breeds of pointers and a spotted Great Dane. Today, it is a popular family pet and many dog enthusiasts enter Dalmatians into kennel club competitions. Characteristics Body The Dalmatian is a muscular dog with excellent endurance and stamina. When fully grown, according to the American Kennel Club (AKC) breed standard, it stands from tall. Coat Dalmatian puppies are born with plain white coats and their first spots usually appear within 10 days; however, spots may be visible on their skin from birth. They continue to develop until the dog is around 18 months old. Spots usually range in size from 2 to 6 cm (1.25 to 2.5 i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chesapeake Bay Retriever
The Chesapeake Bay Retriever is a large breed of dog belonging to the retriever, gundog, and sporting breed groups. The breed was developed in the United States Chesapeake Bay area during the 19th century. Historically used by local market hunters to retrieve waterfowl, pull fishing nets, and rescue fishermen, it is today primarily a family pet and hunting companion, known for a bright and happy disposition; courage; willingness to work; alertness; intelligence; love of water; and hunting capabilities. The Chesapeake is a medium- to large-sized dog similar in appearance to the Labrador Retriever, but with a wavy coat. Appearance Distinctive features include eyes that are very clear, of yellowish or amber hue, hindquarters as high or a trifle higher than the shoulders, and a double-coat that tends to wave on shoulders, neck, back, and loins. The waterproof coat feels slightly oily and is often associated with a slight musky odor. Three basic colors are generally seen in the breed: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boxer (dog)
The Boxer is a medium to large, short-haired dog breed of mastiff-type, developed in Germany. The coat is smooth and tight-fitting; colors are fawn, brindled, or white, with or without white markings. Boxers are brachycephalic (they have broad, short skulls), have a square muzzle, mandibular prognathism (an underbite), very strong jaws, and a powerful bite ideal for hanging on to large prey. The Boxer was bred from the Old English Bulldog and the now extinct Bullenbeisser, which became extinct by crossbreeding rather than by a decadence of the breed. The Boxer is a member of both The Kennel Club and American Kennel Club (AKC) Working Group.http://www.akc.org/dog-breeds/boxer/#standard "Get to Know the Boxer", 'The American Kennel Club', Retrieved 14 May 2014 The first Boxer club was founded in 1895, with Boxers being first exhibited in a dog show for St. Bernards in Munich the next year. Based on 2013 AKC statistics, Boxers held steady as the seventh-most popular breed of dog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Akita
The is a historic dog breed of large size originating from the mountains of northern Japan. The two separate varieties of Akita are a pure Japanese strain, commonly called Akita-ken (''ken'' is the on'yomi for ''inu'' meaning dog in Japanese), and a mixed American strain, commonly larger. The Akita has a short double coat similar to that of many other northern spitz breeds. The Akita is a powerful, independent, and dominant breed, commonly aloof with strangers, but affectionate and deeply loyal with its family. As a breed, Akitas are generally hardy. Historically they were used as guard dogs, fighting dogs and for the hunting of bears. Breed name Debate exists among fanciers whether these are two separate breeds of Akitas. As of 2020, the American Kennel Club, now considers American and Japanese Akitas to be two separate breeds, no longer allowing free breeding between the two. The United Kennel Club, the Federation Cynologique Internationale, The Kennel Club, the Australian Nati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alaskan Malamute
The Alaskan Malamute () is a large breed of dog that was originally bred for its strength and endurance to haul heavy freight as a sled dog and hound. It is similar to other arctic breeds such as the husky, the spitz, the Greenland Dog, Canadian Eskimo Dog, the Siberian Husky, and the Samoyed. Lineage Although it is believed that the first dogs arrived in the Americas 12,000 years ago, people and their dogs did not settle in the Arctic until the Paleo-Eskimo people 4,500 years ago, followed by the Thule people 1,000 years ago, with both originating from Siberia. Malamutes were thought to be bred by the Malimiut Inupiaq people of Alaska's Norton Sound region. The Malamute has been identified as a basal breed that predates the emergence of the modern breeds in the 19th century. A study in 2013 showed that the Alaskan Malamute has a similar east Asian origin to, but is not clearly related to, the Greenland Dog and the Canadian Eskimo Dog, but contains a possible admixture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. Some common naturally occurring steroid hormones are cortisol (), corticosterone (), cortisone () and aldosterone (). (Note that cortisone and aldosterone are isomers.) The main corticosteroids produced by the adrenal cortex are cortisol and aldosterone. Classes * Glucocorticoids such as cortisol affect carbohydrate, fat, and protein metabolism, and have anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive effects. Anti-inflammatory effects are mediated by blocking the action of inflammatory medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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