Hyperacuity
The sharpness of our senses is defined by the finest detail we can discriminate. Visual acuity is measured by the smallest letters that can be distinguished on a chart and is governed by the anatomical spacing of the mosaic of sensory elements on the retina. Yet spatial distinctions can be made on a finer scale still: misalignment of borders can be detected with a precision up to 10 times better than visual acuity, as already shown by Ewald Hering in 1899. This hyperacuity, transcending by far the size limits set by the retinal 'pixels', depends on sophisticated information processing in the brain. How does hyperacuity differ from traditional acuity? The best example of the distinction between acuity and hyperacuity comes from vision, for example when observing stars on a night sky. The first stage is the optical imaging of the outside world on the retina. Light impinges on the mosaic of receptor sense cells, rods and cones, which covers the retinal surface without gaps or ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vernier Acuity
Vernier acuity (from the term "vernier scale", named after astronomer Pierre Vernier) is a type of visual acuity – more precisely of hyperacuity – that measures the ability to discern a disalignment among two line segments or gratings. A subject's vernier (IPA: ) acuity is the smallest visible offset between the stimuli that can be detected. Because the disalignments are often much smaller than the diameter and spacing of retinal receptors, vernier acuity requires neural processing and "pooling" to detect it. Because vernier acuity exceeds acuity by far, the phenomenon has been termed hyperacuity. Vernier acuity develops rapidly during infancy and continues to slowly develop throughout childhood. At approximately three to twelve months old, it surpasses grating acuity in foveal vision in humans. However, vernier acuity decreases more quickly than grating acuity in peripheral vision. Vernier acuity was first explained by Ewald Hering in 1899, based on earlier data by Alfred V ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Superresolution
Super-resolution imaging (SR) is a class of techniques that enhance (increase) the resolution of an imaging system. In optical SR the diffraction limit of systems is transcended, while in geometrical SR the resolution of digital imaging sensors is enhanced. In some radar and sonar imaging applications (e.g. magnetic resonance imaging (MRI), high-resolution computed tomography), subspace decomposition-based methods (e.g. MUSIC) and compressed sensing-based algorithms (e.g., SAMV) are employed to achieve SR over standard periodogram algorithm. Super-resolution imaging techniques are used in general image processing and in super-resolution microscopy. Basic concepts Because some of the ideas surrounding super-resolution raise fundamental issues, there is need at the outset to examine the relevant physical and information-theoretical principles: * Diffraction limit: The detail of a physical object that an optical instrument can reproduce in an image has limits that are mandate ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ewald Hering (1899) Fig 2
Karl Ewald Konstantin Hering (5 August 1834 – 26 January 1918) was a German physiologist who did much research into color vision, binocular perception and eye movements. He proposed opponent color theory in 1892. Born in Gersdorf, Saxony, Alt-Gersdorf, Kingdom of Saxony, Hering studied at the University of Leipzig and became the first rector of the Karl-Ferdinands-Universität, German Charles-Ferdinand University in Prague. Biography Early years Hering was born in Altgersdorf in Saxony, Germany. He probably grew up in a poor family, son of a Lutheran pastor. Hering attended gymnasium in Zittau and entered the university of Leipzig in 1853. There he studied philosophy, zoology and medicine. He completed an M.D. degree in 1860. It is somewhat unclear how Hering trained to do research. At the time Johannes Peter Müller was perhaps the most famous physiologist in Germany. Hering seems to have applied for studying under his direction but was rejected, which might have cont ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ewald Hering
Karl Ewald Konstantin Hering (5 August 1834 – 26 January 1918) was a German physiologist who did much research into color vision, binocular perception and eye movements. He proposed opponent color theory in 1892. Born in Alt-Gersdorf, Kingdom of Saxony, Hering studied at the University of Leipzig and became the first rector of the German Charles-Ferdinand University in Prague. Biography Early years Hering was born in Altgersdorf in Saxony, Germany. He probably grew up in a poor family, son of a Lutheran pastor. Hering attended gymnasium in Zittau and entered the university of Leipzig in 1853. There he studied philosophy, zoology and medicine. He completed an M.D. degree in 1860. It is somewhat unclear how Hering trained to do research. At the time Johannes Peter Müller was perhaps the most famous physiologist in Germany. Hering seems to have applied for studying under his direction but was rejected, which might have contributed to his animosity towards Hermann von H ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Visual Acuity
Visual acuity (VA) commonly refers to the clarity of vision, but technically rates an examinee's ability to recognize small details with precision. Visual acuity is dependent on optical and neural factors, i.e. (1) the sharpness of the retinal image within the eye, (2) the health and functioning of the retina, and (3) the sensitivity of the interpretative faculty of the brain. The most commonly referred visual acuity is the far acuity (e.g. 6/6 or 20/20 acuity), which describes the examinee's ability to recognize small details at a far distance, and is relevant to people with myopia; however, for people with hyperopia, the near acuity is used instead to describe the examinee's ability to recognize small details at a near distance. A common cause of low visual acuity is refractive error (ametropia), errors in how the light is refracted in the eyeball, and errors in how the retinal image is interpreted by the brain. The latter is the primary cause for low vision in people with a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Braille
Braille (Pronounced: ) is a tactile writing system used by people who are visually impaired, including people who are Blindness, blind, Deafblindness, deafblind or who have low vision. It can be read either on Paper embossing, embossed paper or by using refreshable braille displays that connect to computers and smartphone devices. Braille can be written using a slate and stylus, a braille writer, an electronic braille notetaker or with the use of a computer connected to a braille embosser. Braille is named after its creator, Louis Braille, a Frenchman who lost his sight as a result of a childhood accident. In 1824, at the age of fifteen, he developed the braille code based on the French alphabet as an improvement on night writing. He published his system, which subsequently included musical notation, in 1829. The second revision, published in 1837, was the first Binary numeral system, binary form of writing developed in the modern era. Braille characters are formed using a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Clinical Trials
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Perimetry
A visual field test is an eye examination that can detect dysfunction in central and peripheral vision which may be caused by various medical conditions such as glaucoma, stroke, pituitary disease, brain tumours or other neurological deficits. Visual field testing can be performed clinically by keeping the subject's gaze fixed while presenting objects at various places within their visual field. Simple manual equipment can be used such as in the tangent screen test or the Amsler grid. When dedicated machinery is used it is called a perimeter. The exam may be performed by a technician in one of several ways. The test may be performed by a technician directly, with the assistance of a machine, or completely by an automated machine. Machine-based tests aid diagnostics by allowing a detailed printout of the patient's visual field. Other names for this test may include perimetry, Tangent screen exam, Automated perimetry exam, Goldmann visual field exam, or brand names such as Hen ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stereopsis
Stereopsis () is the component of depth perception retrieved through binocular vision. Stereopsis is not the only contributor to depth perception, but it is a major one. Binocular vision happens because each eye receives a different image because they are in slightly different positions on one’s head (left and right eyes). These positional differences are referred to as "horizontal disparities" or, more generally, " binocular disparities". Disparities are processed in the visual cortex of the brain to yield depth perception. While binocular disparities are naturally present when viewing a real three-dimensional scene with two eyes, they can also be simulated by artificially presenting two different images separately to each eye using a method called stereoscopy. The perception of depth in such cases is also referred to as "stereoscopic depth". The perception of depth and three-dimensional structure is, however, possible with information visible from one eye alone, such as diffe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Animal Echolocation
Echolocation, also called bio sonar, is a biological sonar used by several animal species. Echolocating animals emit calls out to the environment and listen to the echoes of those calls that return from various objects near them. They use these echoes to locate and identify the objects. Echolocation is used for navigation, foraging, and hunting in various environments. Echolocating animals include some mammals (most notably Laurasiatheria) and a few birds, especially some bat species and odontocetes (toothed whales and dolphins), but also in simpler forms in other groups such as shrews, and two cave-dwelling bird groups, the so-called cave swiftlets in the genus ''Aerodramus'' (formerly ''Collocalia'') and the unrelated oilbird ''Steatornis caripensis''. Early research The term ''echolocation'' was coined in 1938 by the American zoologist Donald Griffin, who, with Robert Galambos, first demonstrated the phenomenon in bats. As Griffin described in his book, the 18th century I ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Electric Fish
An electric fish is any fish that can generate electric fields. Most electric fish are also electroreceptive, meaning that they can sense electric fields. The only exception is the stargazer family. Electric fish, although a small minority, include both oceanic and freshwater species, and both cartilaginous and bony fishes. Electric fish produce their electrical fields from an electric organ. This is made up of electrocytes, modified muscle or nerve cells, specialized for producing strong electric fields, used to locate prey, for defence against predators, and for signalling, such as in courtship. Electric organ discharges are two types, pulse and wave, and vary both by species and by function. Electric fish have evolved many specialised behaviours. The predatory African sharptooth catfish eavesdrops on its weakly electric mormyrid prey to locate it when hunting, driving the prey fish to develop electric signals that are harder to detect. Bluntnose knifefishes produce an el ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cochlea
The cochlea is the part of the inner ear involved in hearing. It is a spiral-shaped cavity in the bony labyrinth, in humans making 2.75 turns around its axis, the modiolus. A core component of the cochlea is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating the fluid chambers in the coiled tapered tube of the cochlea. The name cochlea derives . Structure The cochlea (plural is cochleae) is a spiraled, hollow, conical chamber of bone, in which waves propagate from the base (near the middle ear and the oval window) to the apex (the top or center of the spiral). The spiral canal of the cochlea is a section of the bony labyrinth of the inner ear that is approximately 30 mm long and makes 2 turns about the modiolus. The cochlear structures include: * Three ''scalae'' or chambers: ** the vestibular duct or ''scala vestibuli'' (containing perilymph), which lies superior to the cochlear duct and abuts the oval window ** the ty ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |